Infectious Disease Institute

Conjunctival goblet cells treated with S. aureas

Harvard Medical School Department of Ophthalmology

Michael S. Gilmore, Ph.D.

James Chodosh, M.D., MPH
Marlene L. Durand, M.D.

The Infectious Disease Institute is a Harvard-wide initiative that operates in conjunction with the NIH-sponsored Harvard-wide Program on Antibiotic Resistance/Boston Area Antibiotic Resistance Network. This alliance promotes interdisciplinary collaboration between Harvard affiliate hospitals and industry partners to screen and validate new compounds and for microbial infections—many of which can affect the eye. Members of the Infectious Disease Institute also explore the cellular mechanisms of infection (including host-pathogen interactions) and the genetics of microbial pathogens (such as viruses, bacteria, and fungi) to identify novel therapeutic targets.

Image: Staphylococcus aureus leads to caspase-1 activation in primary conjunctival goblet cells. From: McGilligan VE et al. PLoS One. 2013 Sep 10;8(9):e74010.