Ivana K. Kim, M.D.

Harvard Medical School

Associate Professor of Ophthalmology, Department of Ophthalmology
Co-director, AMD Center of Excellence
Co-director, Ocular Oncology Center of Excellence

Massachusetts Eye and Ear

Director, Retina Clinical Research
Co-Director, Ocular Melanoma Center
Evangelos S. Gragoudas Distinguished Scholar in Retina
Associate Scientist

Research Summary

Center/Research Area Affiliations

Research Summary

Dr. Kim focuses on the medical and surgical treatment of patients with vitreoretinal diseases. Additionally, she conducts clinical and translational research directed toward the development of new therapies for AMD and ocular melanoma. Together with Drs. Margaret DeAngelis and Joan Miller, she has described novel associations of genes such as RORA, ROB01, and CYP24A 1 with AMD that may highlight important pathways in AMD pathogenesis. Dr. Kim has also initiated and participates in various clinical trials involving new therapeutic approaches for uveal melanoma. Additionally, she has an ongoing collaboration with investigators at Massachusetts General Hospital and the Broad Institute evaluating circulating DNA as a biomarker for uveal melanoma progression. 

Research Projects

  1. Investigation of circulating biomarkers in uveal melanoma
  2. Investigation of new therapies for improving visual outcomes in patients with uveal melanoma


1992: B.S., Biological Sciences, Honors and Distinction, Stanford University

1997: M.D., Harvard Medical School

Postgraduate Training

1998: Internship, Medicine, Massachusetts General Hospital

2001: Residency, Ophthalmology, Harvard Medical School

2003: Fellowship, Retina, Massachusetts Eye and Ear

2003: Chief Retina Fellow, Massachusetts Eye and Ear

Academic Appointments

2012-present: Associate Professor of Ophthalmology, Harvard Medical School

2007-2012: Assistant Professor of Ophthalmology, Harvard Medical School

2003-2007: Instructor in Ophthalmology, Harvard Medical School

Professional Memberships

American Ophthalmological Society

American Academy of Ophthalmology

American Society of Retina Specialists

Club Jules Gonin

Macula Society

Retina Society


Research to Prevent Blindness Physician Scientist Award

Evangelos S. Gragoudas Distinguished Retina Scholar

AAO Achievement Award

ASRS Honor Award


Selected Publications

For a full publication list, please see her CV.

Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration. Yonekawa Y, Andreoli C, Miller JB, Loewenstein JI, Sobrin L, Eliott D, Vavvas DG, Miller JW, Kim IK. Am J Ophthalmol. 2013 Jul;156(1):29-35.e2.

CFH and ARMS2 genetic polymorphisms predict response to antioxidants and zinc in patients with age-related macular degeneration. Awh CC, Lane AM, Hawken S, Zanke B, Kim IK. Ophthalmology. 2013 Nov;120(11):2317-23.

Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT) . Hagstrom SA, Ying GS, Pauer GJ, Sturgill-Short GM, Huang J, Callanan DG, Kim IK, Klein ML, Maguire MG, Martin DF; Comparison of AMD Treatments Trials Research Group. Ophthalmology. 2013 Mar;120(3):593-9.

High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Daniels AB, Lee JE, Macconaill LE, Palescandolo E, Van Hummelen P, Adams SM, Deangelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IKInvest Ophthalmol Vis Sci. 2012 Oct 9;53(11):6991-6.

Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, Deangelis MM, Gragoudas E, Duncan LM, Tsao H. PLoS One. 2012;7(4):e35295.

View a complete list of publications on pubmed.gov>>