Dr. Nicolas BuSaba's research interests are in the fields of rhinology and paranasal sinus disorders, as well as sleep-disordered breathing. He has authored and co-authored several papers that focus on improving our understanding of the pathophysiology, genetics, clinical presentation, and medical and surgical treatment of chronic rhinosinusitis and paranasal sinus mucocele.

His research also focuses on outcomes of OSA surgery, outcomes of major head and neck surgery, and length of hospital stay following such surgeries.

He has presented his research at regional and national scientific meetings and has published in peer-reviewed medical journals.

Through his investigations, Dr. BuSaba determined that Connexin gene mutations do not play a major role in the pathogenesis of chronic rhinosinusitis. His research also elucidated the role of nasal inflammation (rhinitis) in the pathogenesis of sinusitis as well as the efficacy of Monteleukast in the treatment of rhinosinusitis with nasal polyposis.

In addition, he has studied the impact of a patient’s age and gender on the clinical presentation of rhinosinusitis and the surgical outcome on these patients. He has collaborated with colleagues in the Sinus Center on developing a management algorithm to treat patients who present with epistaxis.

Dr. BuSaba's current research initiatives include:

• The accuracy of sinus CT versus physical examination in predicting the severity of nasal septum deviation
• Volumetric analysis of silent sinus syndrome/atelectatic maxillary sinus
• The role of nasal surgery in the management of patients who suffer from sleep-disordered breathing (snoring and/or sleep apnea)

Education
BSc, Biology-Chemistry, American University of Beirut
MD, American University of Beirut

Postgraduate Training
Internship, Department of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School
Residency, Otolaryngology, Mass. Eye and Ear/Harvard Medical School
Clinical/Research Fellowship, General Otolaryngology, Mass. Eye and Ear/Harvard Medical School

Professional Societies
American Board of Otolaryngology
American Academy of Otolaryngology–Head and Neck Surgery
Association of Research in Otolaryngology
Association of Veterans’ Administration Otolaryngologists
Society of Veterans’ Administration Surgeons
New England Otolaryngology Society Massachusetts
Society of Otolaryngology–Head and Neck Surgery
American Rhinologic Society (Chair, International Committee)
American Broncho-Esophalogical Association
American College of Surgeons
American Academy of Otolaryngic Allergy Fellow, Triologic Society Fellow, American Rhinologic Society

Honors
MD with Distinction, American University of Beirut, Beirut, Lebanon
Resident Travel Award, Association of Research in Otolaryngology
Daiichi Clinical Scholars Program in Evidence-Based Medical Research
Honor Award, American Academy of Otolaryngology–Head and Neck Surgery Foundation
First Prize, Best Poster presentation at the Eastern Section Meeting of the Triologic Society