Jason Comander, M.D., Ph.D.

Associate Director, Inherited Retinal Disorders Service


Inherited Retinal Disorders


Macular Degeneration

Board Certification

  • Ophthalmology

Main Campus
243 Charles Street
Boston, MA 02114
Phone: ERG: 617-573-3621; Retina (Boston): 617-573-3871



Dr. Jason Comander is a member of the Mass. Eye and Ear Inherited Retinal Disorders Service and Retina Service, where he specializes in diagnosing and treating inherited retinal diseases. He is also a member of the Ocular Genomics Institute, the Berman-Gund Laboratory for Retinal Degenerations, and the Howe Laboratory.

Dr. Comander is a graduate of Harvard Medical School (HMS), where he earned his medical degree and his PhD in Experimental Pathology. He completed a clinical fellowship at Brigham and Women's Hospital, followed by an ophthalmology residency in Harvard Ophthalmology.

As a clinician-scientist, Dr. Comander's research primarily focuses on the genetics and treatment of inherited retinal diseases. He has studied the genetic basis of distinct forms of retinitis pigmentosa, investigated methods to assay the functional significance of human mutations, and tested techniques for retinal gene therapy in primates.  He also is an investigator and surgeon for a number of ongoing clinical trials for patients with inherited retinal disorders.

A driven and industrious clinician with a demonstrated aptitude for research, Dr. Comander was selected to attend the Heed Foundation Retreat for Academic Ophthalmology in 2009. In 2012, he was recognized as an up-and-coming clinician scientist when he received the highly competitive K12 Mentored Clinical Scientist Development Program Award from the National Institutes of Health, to support his research on inherited retinal disorders. He also holds a Career Development Award from Research to Prevent Blindness and an Enhanced Career Development Award from the Foundation Fighting Blindness.

Clinical Interests

Inherited retinal disorders such as retinitis pigmentosa and Stargardt disease

Retinal disorders including macular degeneration, retinal detachment, macular hole, and epiretinal membrane 


For a full publication list, please see his CV.

Course of Ocular Function in PRPF31 Retinitis Pigmentosa. Hafler BP, Comander J, Weigel DiFranco C, Place EM, Pierce EA. Semin Ophthalmol. 2016;31(1-2):49-52. 

Efficient In Silico Identification of a Common Insertion in the MAK Gene which Causes Retinitis Pigmentosa. Bujakowska KM, White J, Place E, Consugar M, Comander J. PLoS One. 2015 Nov 11;10(11):e0142614.

Visual Function in Carriers of X-Linked Retinitis Pigmentosa. Comander J, Weigel-DiFranco C, Sandberg MA, Berson EL. Ophthalmology. 2015 Sep;122(9):1899-906. 

Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. Mantopoulos D, Murakami Y, Comander J, Thanos A, Roh M, Miller JW, Vavvas DG. PLoS One. 2011; 6(9):e24245.

Diagnostic testing and disease monitoring in birdshot chorioretinopathy. Comander J, Loewenstein J, Sobrin L. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5): 329-36.

View a list of publications on pubmed.gov>>

To learn more about Dr. Comander, read his "Meet a Specialist" profile here.



  • Biology, Harvard College, AB
  • Harvard Medical School, M.D.
  • Experimental Pathology, Harvard Medical School, Ph.D.


  • Ophthalmology, Harvard Medical School


  • Vitreoretinal Surgery, Mass. Eye and Ear