Joseph B. Ciolino, M.D.

Henry Freeman Allen Cornea Scholar


Cornea and External Diseases

Corneal Cross-linking


Board Certification

  • Ophthalmology

Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-3938
Fax: 617-573-4324



Dr. Ciolino is a member of the Cornea Service and the Henry Freeman Allen Cornea Scholar. His clinical focus is in corneal transplants, keratoprosthesis, corneal cross-linking, and diseases of the anterior segment of the eye. As a clinician scientist, his research interests include translational projects such as keratoprosthesis and ocular drug delivery. In addition to his practice at Mass. Eye and Ear, Dr. Ciolino also sees patients at Andover Eye Associates at138 Haverhill St. in Andover, MA. (978-475-0705).

Dr. Ciolino earned his medical degree from Georgetown University School of Medicine and subsequently pursued an ophthalmology residency at Albany Medical College, where he served as Chief Resident in his final year. Returning to Boston for a two-year fellowship in the Cornea, Refractive Surgery and External Disease Service, he received the nationally recognized Claes Dohlman Fellowship Award. He then joined Harvard Medical School's full time faculty at Mass. Eye and Ear under the K12 Harvard-Vision Clinical Scientist Development Program, a highly competitive institutional program funded by the National Institutes of Health.

Working with collaborators at Boston Children's Hospital and Massachusetts Institute of Technology, Dr. Ciolino has developed a drug-eluting contact lens capable of delivering various pharmaceutical agents, such as antibiotics, antifungals, and glaucoma medication. These drug-eluting lenses have the potential to improve surgical outcomes for patients with keratoprosthesis by both protecting the ocular surface of the eye and by preventing post-operative infections, and they may one day replace eye drops.

In addition to his clinical practice and his research program, Dr. Ciolino also supervises medical students and participates in training residents and fellows. He is a named inventor on a U.S. patent application for a contact lens drug delivery device, and his research innovations have multiple direct therapeutic applications that may ultimately benefit a broad and diverse patient population.

Clinical Interests

Corneal transplants, keratoprosthesis, corneal cross-linking, diseases of the anterior segment of the eye

Research Interests

Keratoprosthesis, ocular drug delivery


For a full publication list, please see his CV.

In vivo performance of a drug-eluting contact lens to treat glaucoma for a month. Ciolino JB, Stefanescu CF, Ross AE, Salvador-Culla B, Cortez P, Ford EM, Wymbs KA, Sprague SL, Mascoop DR, Rudina SS, Trauger SA, Cade F, Kohane DS. Biomaterials. 2014 Jan;35(1):432-9.

A drug-eluting contact lens. Ciolino JB, Hoare TR, Iwata NG, Behlau I, Dohlman CH, Langer R, Kohane DS. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7): 3346-52.

A prototype antifungal contact lens. Ciolino JB, Hudson SP, Mobbs AN, Hoare TR, Iwata NG, Fink GR, Kohane DS.  Invest Ophthalmol Vis Sci. 2011 Aug; 52(9): 6286-91.

Retention of the Boston Keratoprosthesis type 1: multicenter study results. Ciolino JB, Belin MW, Todani A, Al-Arfaj K, Ciolino JB. Ophthalmology. 2013 Jun;120(6):1195-200.

Reliable intraocular pressure measurement using automated radio-wave telemetry. Paschalis E, Cade F, Melki SA, Pasquale LR, Dohlman CH, Ciolino JB. Clin Ophthalmol. 2014 Jan 7;8:177-85.

View a list of publications on>>

To learn more about Dr. Ciolino, read his "Meet a Specialist" profile here.



  • Economics, Boston College, BS
  • Georgetown University School of Medicine, M.D.


  • Brown Medical School, Rhode Island Hospital


  • Ophthalmology, Albany Medical College


  • Cornea, Refractive Surgery and External Disease, Mass. Eye and Ear