Demetrios Vavvas, M.D., Ph.D.

Co-Director Ocular Regenerative Medical Institute



Macular Degeneration

Board Certification

  • Ophthalmology

Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-6874
Fax: 617-573-3011



Demetrios Vavvas, M.D., Ph.D., is a full-time clinician scientist in the Retina Service of Mass. Eye and Ear, an Associate Professor of Ophthalmology with Harvard Medical School, a Principal Investigator in the Angiogenesis Laboratory, and the incumbent of the Monte J. Wallace Ophthalmology Chair in Retina.

Clinical Interests

AMD (macular degeneration), diabetic retinopathy, oncology

Research Interests

Neuroprotection, melanoma, angiogenesis, retinopathy of prematurity (ROP), diabetes


For a full publication list, please see his CV.

Roh MI, Murakami Y, Thanos A, Vavvas DG, Miller JW. Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment. Invest Ophthalmol Vis Sci. 2011 May; 52(6): 3825-31.

Morizane Y, Thanos A, Takeuchi K, Murakami Y, Kayama M, Trichonas G, Miller J, Foretz M, Viollet B, Vavvas DG. AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts. J Biol Chem. 2011 May 6; 286(18): 16030-8.

Murakami Y, Miller JW, Vavvas DG. RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death. Oncotarget. 2011 Jun; 2(6): 497-509.

Suzuki J, Manola A, Murakami Y, Morizane Y, Takeuchi K, Kayama M, Miller JW, Sobrin L, Vavvas DG. Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 2011 Aug; 52(9): 6565-71.

Chen L, Miller JW, Vavvas D, Kim IK. Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration. Retina.2011 Nov; 31(10): 2078-83.

View a complete list of publications on>>



  • Biology/Neurosciences, McGill University, B.Sc.
  • Boston University School of Medicine, M.D.
  • Physiology, Boston University School of Medicine, Ph.D.


  • Ophthalmology, Harvard Medical School Department of Ophthalmology Residency Training Program


  • Vitreoretinal Surgery, Mass. Eye and Ear