Dr. Rachel Huckfeldt is a full-time member of the Inherited Retinal Disorders Service at Mass. Eye and Ear. She is a retina specialist with expertise in inherited retinal degenerations as well as conditions including age-related macular degeneration and diabetic retinopathy.
Dr. Huckfeldt graduated from Washington University in St. Louis, summa cum laude, with a BA in Biology and Psychology. Subsequently, she earned her MD and PhD in Neuroscience at Washington University. Next, she completed her ophthalmology residency in Harvard Medical School’s Department of Ophthalmology. Before returning to Mass. Eye and Ear, she completed a postdoctoral Research Fellowship in Therapeutics for Inherited Retinal Diseases with Dr. Jean Bennett at the University of Pennsylvania as well as a Medical Retina Fellowship at the University of Iowa. She completed a clinical and research fellowship in inherited retinal degenerations under the guidance of Dr. Eric Pierce, supported by a Foundation Fighting Blindness Clinical/ Research Fellowship Award.
Dr. Huckfeldt’s research focuses on inherited retinal degenerations. Her current research uses multimodal retinal imaging including adaptive optics to probe the genotype-phenotype relationships associated with IRDs and retinitis pigmentosa (RP) in particular.
Dr. Huckfeldt has received numerous honors and awards. In particular, she was selected to attend the Heed Resident’s Retreat, later received a Heed Fellowship, and also received an Association for Research in Vision and Ophthalmology/National Eye Institute travel grant.
Age-related macular degeneration, diabetic retinopathy, retinal vein occlusions, inherited retinal degenerations
Inherited retinal degenerations, retinal imaging
For a full publications list, please see her CV.
Circadian entrainment to temperature, but not light, in the isolated suprachiasmatic nucleus. Herzog ED, Huckfeldt RM. J Neurophysiol. Aug 2003;90(2):763-770.
Transient neurites of retinal horizontal cells exhibit columnar tiling via homotypic interactions. Huckfeldt RM, Schubert T, Morgan JL, et al. Nat Neurosci. Jan 2009;12(1):35-43.
Assembly of the outer retina in the absence of GABA synthesis in horizontal cells. Schubert T, Huckfeldt RM, Parker E, Campbell JE, Wong RO. Neural Dev. 2010;5:15.
Neuroprotection for retinal detachment. Huckfeldt RM, Vavvas DG. Int Ophthalmol Clin. 2013 Fall;53(4):105-17.
Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter. Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J. EMBO Mol Med. 2014;6(9):1175-1190.
Promising first steps in gene therapy for choroideremia. Huckfeldt RM, Bennett J. Hum Gene Ther. 2014 Feb;25(2):96-7.
View a list of publications on pubmed.gov >>