Pediatric patient with physician

Research and Education


Thanks to a wide range of funding sources, including government and private donors, pediatric ear, nose, and throat (ENT) research at Mass. Eye and Ear has resulted in significant breakthroughs and innovations that have advanced medical and surgical treatment. 

Some of our accomplishments include:

  • Advances in ear reconstruction for children with microtia and other congenital ear malformations
  • Contributions in the treatment of newborn airway anomalies and adolescent voice problems
  • Advances in the correction of childhood hearing loss including cochlear implantation
  • Management of hemangiomas and vascular anomalies

Understanding immune-microenvironment of JRRP to uncover immunotherapy for the disease 

Juvenile recurrent respiratory papillomatosis (JRRP) is a HPV-related tumor with the potential to transform into a malignant stage. Previous research has found that dysregulation of immune cells, including enrichment of suppressive regulatory T cells and PD-L1 expression on tumor cells, may contribute to disease pathogenesis. However, the fundamental mechanism leading to this dysregulation remains unclear. In collaboration with Dr. Christopher Hartnick, Dr. Tingyu Liu at Novartis is leading research to understand the immune-microenvironment of JRRP. This collaboration aims to identify immune cell populations and mechanisms contributing to disease control. Their ultimate goal is to seek therapeutic approaches that improve anti-tumor immunity and control tumor growth. 

If you have any questions about this research, feel free to contact Dr. Hartnick at


Mass. Eye and Ear is considered a valuable pediatrics training resource. Some of our major educational commitments include:

  • Residency training: All of our surgeons have an active teaching role in the Harvard Otolaryngology Residency Program.
  • Continuing Medical Education: Harvard Medical School sponsored courses have been given for attending level physicians, both in primary care as well as in otolaryngology.
  • Pediatric Otolaryngology Fellowship: Directed by Dr. Christopher Hartnick, we offer a one- or two-year fellowship in pediatric otolaryngology. Those fellows who choose a second year devote that year to advanced education or research.
  • Lectures: Our physicians lecture nationally and internationally on pediatric otolaryngology and have played prominent leadership roles in the field’s major academic societies, including the American Society of Pediatric Otolaryngology.
  • Publications: We publish four journals on quality measures of patient care.