David M. Wu, M.D., Ph.D.

Harvard Medical School

Instructor in Ophthalmology, Department of Ophthalmology

Massachusetts Eye and Ear

Assistant Scientist



Research Summary

Center/Research Area Affiliations

Research Summary

Dr. Wu is performing transcriptome profiling on photoreceptors from healthy and degenerating retinas. His goal is to characterize molecular pathways of retinal disease and identify novel mechanisms that may be targeted to slow photoreceptor loss. Dr. Wu also sees vitreoretinal surgery patients at Mass. Eye and Ear's Longwood and Charles Street locations.

For more information, download his CV [PDF].


1997: B.S. with distinction, Biomedical Science, University of Michigan, Inteflex Program

2003: Ph.D., Neuroscience, University of Michigan

2005: M.D. with distinction in research honors, University of Michigan Medical School

Postgraduate Training

2006: Internship, Grand Rapids Medical Education Partners

2009: Residency, Ophthalmology, University of Michigan W.K. Kellogg Eye Center

2010: Fellowship, Medical Retina/Research, University of Michigan W.K. Kellogg Eye Center

2012: Fellowship, Vitreoretinal Surgery, Doheny Eye Institute, Keck School of Medicine, University of Southern California / Los Angeles County Medical Center

Academic Appointments

2012-present: Instructor in Ophthalmology, Harvard Medical School


Selected Publications

Chincore Y, Begaj T, Wu D, Drokhlyansky E, Cepko CL. Glycolytic reliance promotes anabolism in photoreceptorsElife.  6. pii: e25946. 2017.

Finn AP, Eliott D, Kim LA, Husain D, Wu DM, Young LH, Kim IK, Andreoli C, Skonda D, Vavvas DG, Miller JB. Characteristics and Outcomes of Simultaneous Bilateral Rhegmatogenous Retinal DetachmentsOSLI Retina. 47(9): 840-845. 2016.

Zhang T, Wu DM, Xu G, Puro DG. The electrotonic architecture of the retinal microvasculature: modulation by angiotensin II.  J Physiol. 589(9): 2383-2399. 2011.

Matsushita K, Fukumoto M, Kobayashi T, Kobayashi M, Ishikazi E, Minami M, Katsumura K, Liao SD, Wu DM, Zhang T, Puro DG. Diabetes-induced inhibition of voltage-dependent calcium channels in the retinal microvasculature: role of spermine. IOVS. 51(11): 5979-5990. 2010.

Wu DM, Minami M, Kawamura H, Puro DG. Electrotonic transmission within pericyte-containing retinal microvessels. Microcirculation. 13(5): 353-363. 2006.

View a complete list of publications on pubmed.gov>>