Mengyu Wang, Ph.D.

Harvard Medical School

Instructor in Ophthalmology

Massachusetts Eye and Ear

Investigator

Research Summary

Dr. Mengyu Wang is a multidisciplinary researcher with extensive training in the areas of ophthalmology, radiology, machine learning, medical image analysis, and computational mechanics. Dr. Wang’s current research focuses on developing mathematical models to better understand eye diseases by using the techniques of machine learning, statistics, image processing, and biomechanics to eventually improve the diagnosis, prognosis, and treatment of eye diseases.

Since 2015, his work has been focused on applying mathematical modeling to enhance our understanding of eye diseases. In particular, he identified a novel retinal biomarker for glaucomatous central vision loss, and developed a computational method based on machine learning techniques that substantially reduces the number of false-positive diagnoses of glaucoma. He also demonstrated that the risk of under-correction of myopia after refractive surgery is associated with weak corneal biomechanical properties. He collaborates with several research groups within Harvard Medical School to study structure-function relationships in different eye diseases including glaucoma, non-arteritic anterior ischemic optic neuropathy, and diabetic retinopathy.

Dr. Wang is a co-inventor of two patents related to assessing visual fields in glaucoma with machine learning techniques to assist clinicians to more effectively and accurately interpret visual field test results.

Download his CV [PDF] for more information.

Education

2014: Ph.D., Structural Engineering and Mechanics, University of Pittsburgh

Postgraduate Training

2015: Postdoctoral Associate, Breast Cancer Imaging, Department of Radiology, Duke University

2017: Postdoctoral Fellow, Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School

Academic Appointments

2017-present: Instructor in Ophthalmology, Harvard Medical School

Professional Memberships

2015-present: Association for Research in Vision and Ophthalmology

Honors

2013: Graduate Travel Grant, University of Pittsburgh

2016: First Prize in North America Division, Chunhui Cup Innovation and Entrepreneurship Competition for Chinese Oversea Students and Scholars

2018: Best Scientific Paper of 2017-2018 by a Trainee, Schepens Eye Research Institute of Massachusetts Eye and Ear



Publications

Selected Publications

Dr. Wang has authored 21 peer-reviewed papers across the fields of computational mechanics, cancer imaging, machine learning and ophthalmology. Below is a list of selected publications.

Wang, M., Wang, H., Pasquale, L.R., Baniasadi, N., Shen, L.Q., Bex, P.J. and Elze, T., 2017. Relationship between Central Retinal Vessel Trunk Location and Visual Field Loss in Glaucoma.American Journal of Ophthalmology, 176, 53-60. PMID: 28088508

Elze,T., Baniasadi, N., Jin, Q., Wang, H., and Wang MAmetropia, Retinal Anatomy, and OCT Abnormality Patterns in Glaucoma. 1. Impacts of Refractive Error and Interartery AngleJournal of Biomedical Optics. 22(12), p.121713. 2017

Wang, M., Elze, T., Li, D., Baniasadi, N., Wirkner, K., Kirsten, T., Nuechter, M., Thiery, J., Loeffler, M., Engel, C. and Rauscher, F.G. Age, Ocular Magnification, and Circumpapillary Retinal Nerve Fiber Layer ThicknessJournal of Biomedical Optics. 22(12), p.121718. 2017.

Wang, M., Jin, Q., Wang, H., Li, D., Baniasadi, N. and Elze, T. The Interrelationship between Refractive Error, Blood Vessel Anatomy, and Glaucomatous Visual Field LossTranslational Vision Science and Technology. 7(1), pp.4-4. 2018.

Wang, M., Pasquale, L.R., Shen, L.Q., Boland, M.V., Wellik, S.R., De Moraes, C.G., Myers, J.S., Wang, H., Baniasadi, N., Li, D., Silva, R.N.E., Bex, P.J. and Elze, T., 2018. Reversal of Glaucoma Hemifield Test Results and Visual Field Features in GlaucomaOphthalmology, S0161-6420(17)31710-4. PMID: 29103791

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