David A. Shaye, M.D.

Harvard Medical School

Instructor in Otolaryngology

Massachusetts Eye and Ear

Research Summary

Research Area

Research Summary

Dr. Shaye is active in research to optimize the delivery of high quality, cost-effective surgical care in resource poor settings. He has performed epidemiological research in sub-Saharan Africa examining the geo-spatial distribution of cleft lip and palate deformities in Zimbabwe over a 7-year period. The geographic distribution of patients with cleft lip and palate are used to target and deliver better surgical care.  Other research interests include the use of mobile phone technology to improve surgical follow up in countries with significant geographic constraints. 

Dr. Shaye's research also focuses on the use of intra-operative imaging to perform less invasive, more accurate repair of maxillofacial trauma injuries. Intra-operative imaging with modern, portable CT scanners offers real time information on facial fracture alignment and assists in the precise placement of orbital implants. This can obviate the need for more invasive surgery, leading to quicker recovery, less postoperative pain, and less scarring.

Select Publications

Update on outcomes research for cleft lip and palate. Shaye D. Curr Opin Otolaryngol Head Neck Surg. 2014 May 28. [Epub ahead of print] PubMed PMID: 24874212.

Repair of the supernumerary nostril. Shaye DA, Tibesar RJ. J Craniofac Surg. 2014 May;25(3):978-9. doi: 10.1097/SCS.0000000000000549. PubMed PMID: 24699105.

Chin Augmentation Surgery. David A. Shaye, Jewel D. Greywoode, David D. Hamlar, and Peter A. Hilger. http://rhinoplastyarchive.com.  September 2013.

Comparison of PET imaging with 64Cu-liposomes and 18F-FDG in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch model of oral dysplasia and squamous cell carcinoma. Mahakian LM, Farwell DG, Zhang H, Seo JW, Poirier B, Tinling SP, Afify AM, Haynam EM, Shaye D, Ferrara KW. Mol Imaging Biol. 2014 Apr;16(2):284-92. doi: 10.1007/s11307-013-0676-1. PubMed PMID: 24019092; PubMed Central PMCID: PMC3984137.

The importance of the nasal septum in the deviated nose. Sykes JM, Kim JE, Shaye D, Boccieri A. Facial Plast Surg. 2011 Oct;27(5):413-21. doi: 10.1055/s-0031-1288928. Epub 2011 Oct 25. Review. PubMed PMID: 22028006.

Improving posttraumatic facial scars. Ardeshirpour F, Shaye DA, Hilger PA. Otolaryngol Clin North Am. 2013 Oct;46(5):867-81. doi: 10.1016/j.otc.2013.06.006. Epub 2013 Sep 4. Review. PubMed PMID: 24138743.

Cleft lip and cleft rhinoplasty complications. Kim JE, Sykes JM, Shaye DA. Facial Plast Surg. 2012 Jun;28(3):318-22. doi: 10.1055/s-0032-1312699. Epub 2012 Jun 21. PubMed PMID: 22723233.

Advances in nasal reconstruction. Shaye DA, Sykes JM, Kim JE. Curr Opin Otolaryngol Head Neck Surg. 2011 Aug;19(4):251-6. doi: 10.1097/MOO.0b013e3283486a08. Review. PubMed PMID: 21659879.

Cleft lip and palate. Travis Tollefson and David Shaye. Epocrotes online: British Medical Journal. November 2011.

Review of “Global Surgery: Thoughts on an emerging surgical subspecialty for students and residents.” David Shaye and Travis Tollefson. Faculty of 1000. February 2011. 

Reconstruction of Acquired Ear Deformities. David Shaye & Jonathan Sykes. Operative Techniques in Otolaryngology. March 2011; Vol 22, Issue 1.

A complete list of research publications can be seen at www.pubmed.gov.



1998 - 2002: B.A. Physics (Magna Cum Laude, Sigma Xi, Phi Beta Kappa), Hamilton College
2002 - 2003: Fulbright Fellowship (Research), U.S. Department of State
2003 - 2007: M.D. Albany Medical College (AOA)

Postgraduate Training

2007 - 2008: Internship: General Surgery, University of California, Davis
2008 - 2012: Residency: Otolaryngology–Head and Neck Surgery, University of California, Davis
2012 - 2014: Fellowship: Facial Plastic and Reconstructive Surgery, University of Minnesota

Professional Memberships (select)

Alpha Omega Alpha Honor Medical Society
American Academy of Otolaryngology–Head and Neck Surgery
American Cleft Palate/Craniofacial Association
American Academy of Facial Plastic and Reconstructive Surgery

Honors (select)

2012: Resident Teaching Award, University of California, Davis
2011: AAFPRS Representative
2011: Adjunct Faculty: Unconventional Surgical Immersion Course, Little Rock, AR.
2010: AAO-HNS Humanitarian Travel Award
2010: Research Award for Best Research Presentation, University of California, Davis