About My Research
Centers/Research Area Affiliations
Biography
At Schepens Eye Research Institute of Mass. Eye and Ear, Dr. Shrinivas Pundlik’s main research interests include image processing, computer vision, vision science, vision rehabilitation, and ocular biometrics. After completing his doctoral studies in the electrical engineering, Dr. Pundlik developed novel image processing algorithms for biometric identification using iris and face images. Since 2010, Dr. Pundlik has been engaged in various research projects that involved the application of computer vision and machine learning to develop new technologies and solutions for vision screening and vision rehabilitation. He also developed a wearable collision-warning device to help people with severe vision impairments avoid colliding while walking. He has contributed to the development of numerous mobile apps, either intended as low-vision aids or vision measurement for healthcare professionals. His research has resulted in more than 20 peer-reviewed publications in international journals and conferences, one patent, and a patent application under review.
Education
MS and PhD, Electrical Engineering, Clemson University (2005 and 2009)
Postgraduate Training
Research Associate, School of Computing, Clemson University (2009-2010)
Postdoctoral Fellowship, Schepens Eye Research Institute of Mass. Eye and Ear (2010-2016)
Honors
2018: National Eye Institute Travel Grant, Association for Research in Vision and Ophthalmology
2015: Outstanding Reviewer Recognition, IEEE Transactions on Instrumentation and Measurement
2007: Harris Outstanding Teaching Assistant Award, Electrical and Computer Engineering Department, Clemson University
- Investigation of Population-Based Fall Risk in Eye Diseases. JAMA Ophthalmol. 2024 Feb 01; 142(2):106-107.
- Field Evaluation of a Mobile App for Assisting Blind and Visually Impaired Travelers to Find Bus Stops. Transl Vis Sci Technol. 2024 01 02; 13(1):11.
- Evaluation of a mobile app for dark adaptation measurement in individuals with age-related macular degeneration. Sci Rep. 2023 12 14; 13(1):22191.
- Gaze Scanning at Street Crossings by Pedestrians With Homonymous Hemianopia With and Without Hemispatial Neglect. Invest Ophthalmol Vis Sci. 2023 Nov 01; 64(14):26.
- Impact of Apps as Assistive Devices for Visually Impaired Persons. Annu Rev Vis Sci. 2023 09 15; 9:111-130.
- Comparison of visual SLAM and IMU in tracking head movement outdoors. Behav Res Methods. 2023 09; 55(6):2787-2799.
- Dark Adaptation and Its Role in Age-Related Macular Degeneration. J Clin Med. 2022 Mar 01; 11(5).
- BASELINE PREDICTORS ASSOCIATED WITH 3-YEAR CHANGES IN DARK ADAPTATION IN AGE-RELATED MACULAR DEGENERATION. Retina. 2021 Oct 01; 41(10):2098-2105.
- Home-Use Evaluation of a Wearable Collision Warning Device for Individuals With Severe Vision Impairments: A Randomized Clinical Trial. JAMA Ophthalmol. 2021 Sep 01; 139(9):998-1005.
- Influence of COVID-19 Lockdowns on the Usage of a Vision Assistance App Among Global Users With Visual Impairment: Big Data Analytics Study. J Med Internet Res. 2021 05 12; 23(5):e26283.
- Area under the dark adaptation curve as a reliable alternate measure of dark adaptation response. Br J Ophthalmol. 2022 10; 106(10):1450-1456.
- Delayed dark adaptation in central serous chorioretinopathy. Am J Ophthalmol Case Rep. 2021 Jun; 22:101098.
- A smartphone ocular alignment measurement app in school screening for strabismus. BMC Ophthalmol. 2021 Mar 25; 21(1):150.
- Inpatient Virtual Vision Clinic Improves Access to Vision Rehabilitation Before and During the COVID-19 Pandemic. Arch Rehabil Res Clin Transl. 2021 Mar; 3(1):100100.
- Without low spatial frequencies, high resolution vision would be detrimental to motion perception. J Vis. 2020 08 03; 20(8):29.
- Measuring Virtual Reality Headset Resolution and Field of View: Implications for Vision Care Applications. Optom Vis Sci. 2020 08; 97(8):573-582.
- Data Acquisition, Processing, and Reduction for Home-Use Trial of a Wearable Video Camera-Based Mobility Aid. Transl Vis Sci Technol. 2020 06; 9(7):14.
- Using an Automated Hirschberg Test App to Evaluate Ocular Alignment. J Vis Exp. 2020 03 24; (157).
- A Mobile Application for Keyword Search in Real-World Scenes. IEEE J Transl Eng Health Med. 2019; 7:2900210.
- A Hardware-Friendly Optical Flow-Based Time-to-Collision Estimation Algorithm. Sensors (Basel). 2019 Feb 16; 19(4).
- Development and Preliminary Evaluation of a Smartphone App for Measuring Eye Alignment. Transl Vis Sci Technol. 2019 Jan; 8(1):19.
- Preliminary Evaluation of a Mobile Device for Dark Adaptation Measurement. Transl Vis Sci Technol. 2019 Jan; 8(1):11.
- Preliminary Evaluation of a Wearable Camera-based Collision Warning Device for Blind Individuals. Optom Vis Sci. 2018 09; 95(9):747-756.
- Magnifying Smartphone Screen Using Google Glass for Low-Vision Users. IEEE Trans Neural Syst Rehabil Eng. 2017 01; 25(1):52-61.
- Mobile gaze tracking system for outdoor walking behavioral studies. J Vis. 2016; 16(3):27.
- Evaluation of a Portable Collision Warning Device for Patients With Peripheral Vision Loss in an Obstacle Course. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2571-9.
- Real-time motion segmentation of sparse feature points at any speed. IEEE Trans Syst Man Cybern B Cybern. 2008 Jun; 38(3):731-42.
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Wearable Collision-Warning Device
Dr. Pundlik's collision-warning devicePeople with visual impairments, especially those with peripheral vision loss or blindness, often experience mobility related challenges and have a high risk of collisions or falls while walking. Dr. Pundlik is developing a wearable video camera-based collision warning device that detects impending collisions by processing videos captured from a body-mounted camera in real time, and provides audio or vibro-tactile warnings. The device computes collision risk based on the time-to-collision and the collision trajectory of objects in the surrounding environment captured by the body-mounted camera. The device has been shown to be effective in lowering the number of collisions in an indoor obstacle course in people with severe visual impairments and peripheral vision loss. Evaluation of the device in a long-term home use study is ongoing.
Mobile App for Measuring Strabismus
Dr. Pundlik's strabismus appStrabismus, or eye misalignment, affects about 3-8 percent of Americans. Children younger than 10 years of age and older adults with head trauma due to stroke or injury are primarily at risk of developing strabismus. In children, untreated eye misalignment can lead to amblyopia (severe loss of vision in the misaligned eye). In adults, it can lead to double vision, spatial confusion, and diminished depth perception, if left untreated. Early screening in children can substantially reduce the risk of developing vision defects. In adults, an objective measurement can facilitate appropriate intervention to alleviate double vision. However, there is an unmet need for a rapid, convenient, accessible, and inexpensive device that can provide objective assessment outcomes to clinicians. Dr. Pundlik has developed a mobile app to measure eye misalignment that allows an examiner to capture image(s) of the patient from a smartphone and provides quantifiable measurements of strabismus. Further development, addition of various operating features, and clinical testing of the app is ongoing.
Smartphone Virtual Reality Apps for Vision Rehabilitation
Virtual reality app for vision rehabilitationBrain injury due to trauma or stroke sometimes affects the nerves that control movements of the eyes that results in misalignment of eyes only at specific gaze directions such as when looking below or above. Measurement of eye deviation at different gaze points can be important to determine the underlying cause and effective intervention to alleviate the problem. The smartphone virtual reality headsets provide an inexpensive platform for performing the sensorimotor tests of the eyes. Dr. Pundlik has developed a virtual reality app in which the patient performs a vision test of aligning two stimuli presented dichoptically while wearing the virtual reality headsets. This makes administering the test efficient and more repeatable. Preliminary research found that the app can accurately measure eye deviation at different gaze points in simulated scenarios. Dr. Pundlik is currently performing an extended evaluation of this app in outpatient and rehabilitation clinics.
Understanding of Saccadic Eye Movements in Naturalistic Viewing Tasks
Saccadic eye movements, or saccades, are fast ballistic movements of the eyes between fixations (steady gaze). Saccades are characterized by latency, peak-speed, amplitude, and duration. Under controlled viewing conditions, the saccades parameters generally tend to follow a well-known model: the main sequence. The deviation of saccades from this model has been reported in the case of various vision and neurological defects. However, we have observed large deviations from this model in saccades even in normally sighted subjects without any cognitive or neurological defects when viewing unconstrained visual stimuli such as movies. Dr. Pundlik is working on developing a model that explains the variance in the observed naturalistic eye movement data with the expectation that it will provide some insight into the neuronal processes involved in saccadic eye movement planning and execution.