Adrian J. Priesol, M.D.

Harvard Medical School

Assistant Professor of Otolaryngology

Massachusetts Eye and Ear

Medical Director, Auditory Evoked Response Testing

Research Summary

Research Area Affiliations

Research Summary

Dr. Priesol’s research involves applying vestibular perceptual testing to central and peripheral vestibular disorders. He has studied vestibular migraine and has shown that perceptual thresholds (i.e. the smallest motion that can be detected reliably) to roll-tilt are reduced in patients with vestibular migraine but not in subjects with only migraine headaches. The reduced thresholds were most pronounced at mid frequencies, indicating abnormal integration of vertical canal and otolith signals in patients with vestibular migraine. More recent studies of vestibular perceptual thresholds in patients with idiopathic bilateral vestibulopathy demonstrated relative sparing of otolith and vertical canal function despite the severe loss of horizontal canal function that defines this condition.

Select Publications

Motion Perception in Patients with Idiopathic Bilateral Vestibular Hypofunction. Priesol AJ, Valko Y, Merfeld DM, Lewis RF. Otolaryngol Head Neck Surg. 2014 Mar 19. [Epub ahead of print]

Frequency-dependent effects of glutamate antagonists on the vestibulo-ocular reflex of the cat. Priesol AJ, Jone GE, Tomlinson RD, and Broussard DM.  (2000)  Brain Research, 857 (1-2):252-64.

Potential solutions to several vestibular challenges facing clinicians.  Merfeld D, Priesol AJ, Lee D, Lewis RF. (2010) Journal of Vestibular Research, 20(1):71-7.

Abnormal motion perception in vestibular migraine. Lewis, RF, Priesol AJ, Nicoucar K, Lim K, and Merfeld DM. (2011) Laryngoscope, 121(5): 1124-5.

Dynamic tilt thresholds are reduced in vestibular migraine. Lewis, RF, Priesol AJ, Nicoucar K, Lim K, and Merfeld DM. (2011) Journal of Vestibular Research 21(6): 323-30.

Vestibular Labyrinth Contributions to Human Whole-Body Motion Discrimination. Valko Y, Lewis R, Priesol A, and Merfeld D. J Neuroscience 2012; 32(39):13537-42.

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