Nahyoung Grace Lee,
MD
Massachusetts Eye and Ear
Associate Scientist
Harvard Medical School
Associate Professor of Ophthalmology
grace_lee@MEEI.HARVARD.EDU
For investigator inquiries only
About My Research
Center/Research Area Affiliations
Research Summary
Dr. Lee’s research interests include orbital disease and tumors as well as thyroid eye disease. She is particularly interested in studying the potential role of vasculogenesis in thyroid eye disease. She is also involved in developing a mouse model of orbital inflammation.
Education
2006: MD, Johns Hopkins University
Postgraduate Training
2007-2010: Ophthalmology Resident, University of Southern California/Doheny Eye Institute
2010-2011: Ophthalmic Pathology/Oncology Fellow, Oregon Health & Science University/Casey Eye Institute
2011-2014: Ophthalmic Plastic and Reconstructive Surgery Fellow, Harvard Medical School/Mass. Eye and Ear
Academic Appointments
2014-2016: Instructor in Ophthalmology, Harvard Medical Schhol
2016-2021: Assistant Professor of Ophthalmology, Harvard Medical School
2021-Present: Associate Professor of Ophthalmology, Harvard Medical School
Professional Memberships
2008-present: Member, Association for Research in Vision and Ophthalmology
2011-present: Fellow, American Academy of Ophthalmology
2011-present: Diplomat, American Board of Ophthalmology
2013-present: Member, Women in Ophthalmology
2013-present: Member, Women in Ocular Oncology
2014-present: Member, New England Ophthalological Society
Honors
2003: Research Scholar Award, National Science Foundation
2006: Harold Lamport Student research Award, Johns Hopkins School of Medicine
2009: National Eye Institute Travel Grant, Association for Research in Vision and Ophthalmology
2010: Doheny Eye Institute Medical Knowledge Award
2012: Resident/Fellow Research Form, Association of University Professors in Ophthalmology
2013: Fellow of the year Teaching Award, Mass. Eye and Ear
2013-2014: Heed Fellow, Heed Foundation
Publications powered by Harvard Catalyst Profiles
- Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation. Orbit. 2024 Apr 03; 1-4.
- Change in upper eyelid position after teprotumumab treatment for thyroid eye disease. Orbit. 2024 Mar 11; 1-7.
- Antisynthetase Syndrome Causing Necrotizing Myositis Involving Extraocular Muscles. Ophthalmic Plast Reconstr Surg. 2024 Feb 09.
- Melanoma Arising Beneath the Lateral Rectus Muscle in a Teenager With Ocular Melanocytosis: Possible Origin From Intrascleral Melanocytes. Ophthalmic Plast Reconstr Surg. 2024 Feb 09.
- A Deep Learning Model for Screening Computed Tomography Imaging for Thyroid Eye Disease and Compressive Optic Neuropathy. Ophthalmol Sci. 2024 Jan-Feb; 4(1):100412.
- Proptosis Regression After Teprotumumab Treatment for Thyroid Eye Disease. Ophthalmic Plast Reconstr Surg. 2024 Mar-Apr 01; 40(2):187-191.
- Hyperglobus and Pseudoptosis in Type 1 Lipogenic Thyroid Eye Disease. Am J Ophthalmol Case Rep. 2023 Dec; 32:101890.
- Upper portion of the eyelid blepharoplasty for a patient with recalcitrant Morbihan disease. JAAD Case Rep. 2023 Aug; 38:102-104.
- Tackling prediction uncertainty in machine learning for healthcare. Nat Biomed Eng. 2023 06; 7(6):711-718.
- Intrusion, Extrusion, and Infection of a Hydrolyzed MIRAgel Scleral Buckle. Am J Ophthalmol. 2023 03; 247:e1-e2.
- Clear Cell Syringoma of the Eyelids, a Distinctive Histopathologic Variant Associated with Diabetes Mellitus. Ophthalmic Plast Reconstr Surg. 2023 Jan-Feb 01; 39(1):e20-e22.
- Orbital Inflammation Following COVID-19 Vaccination. Ophthalmic Plast Reconstr Surg. 2022 May-Jun 01; 38(3):e67-e70.
- Granular Cell Tumor of the Orbit: Review of the Literature and a Proposed Treatment Modality. Ophthalmic Plast Reconstr Surg. 2022 Mar-Apr 01; 38(2):122-131.
- Bilateral Panuveitis and Myeloradiculopathy in a 12-Year-Old Girl. JAMA Ophthalmol. 2022 02 01; 140(2):203-204.
- Infiltrative Sebaceous Carcinoma Presenting as a Tumor Tarsorrhaphy. Ophthalmic Plast Reconstr Surg. 2022 Jan-Feb 01; 38(1):e35.
- Temporalis Muscle Abscess With Secondary Extension Into the Orbit. Ophthalmic Plast Reconstr Surg. 2021 Jan-Feb 01; 37(1):e38.
- Lower eyelid malposition following repair of complex orbitofacial trauma. Orbit. 2022 Apr; 41(2):193-198.
- Granulomatosis with polyangiitis presenting as recurrent, multifocal orbital myositis. Orbit. 2021 Dec; 40(6):529-531.
- Characterization of a Murine Model of Oxazolone-Induced Orbital Inflammation. Transl Vis Sci Technol. 2020 07; 9(8):26.
- Pyoderma gangrenosum of the eyelid associated with inflammatory bowel disease. Am J Ophthalmol Case Rep. 2020 Jun; 18:100623.
- Ocular Adnexal Adenomatoid Sebaceous Gland Hyperplasia: A Clinical and Immunopathologic Analysis in Relation to the Muir-Torre Syndrome. Ophthalmic Plast Reconstr Surg. 2020 Jan/Feb; 36(1):e6-e12.
- Clinical and radiographic features of hydrolyzed MIRAgel scleral buckles: A comparative analysis. Clin Imaging. 2020 Mar; 60(1):10-15.
- Complex Intratarsal Cyst with a Mixed Ciliated Respiratory-Type and Squamous Epithelial Lining. Ocul Oncol Pathol. 2020 May; 6(3):151-158.
- Basal Cell Carcinoma Masquerading as a Chalazion in a 27-Year-Old Woman. JAMA Ophthalmol. 2019 Jul 01; 137(7):e185435.
- Visual field and orbital computed tomography correlation in dysthyroid optic neuropathy due to thyroid eye disease. Orbit. 2020 Apr; 39(2):77-83.
- Ophthalmic Plastic Surgery in Patients 100 Years and Older. Ophthalmic Plast Reconstr Surg. 2019 Jan/Feb; 35(1):71-76.
- Atypical Case of Rosai-Dorfman Disease of the Lacrimal Gland with Adjacent Bone Erosion. Ocul Oncol Pathol. 2019 Feb; 5(2):128-134.
- Bilateral Periorbital Impetigo Inducing Significant Dermatitis and Cicatricial Eyelid Changes in an Adult. Ophthalmology. 2018 06; 125(6):798.
- Simultaneous ipsilateral transconjunctival repair of upper and lower eyelid retraction in thyroid-associated ophthalmopathy. Orbit. 2019 Apr; 38(2):124-129.
- Revision eDCR using a superior pedicled mucosal flap. Orbit. 2019 Feb; 38(1):1-6.
- A Lacrimal Gland Choristoma of the Lacrimal Sac. Ophthalmic Plast Reconstr Surg. 2018 Jan/Feb; 34(1):e3-e6.
- Complications Assoicated with MIRAgel for Treatment of Retinal Detachment. Semin Ophthalmol. 2018; 33(1):89-94.
- Exophytic Osteochondroma of the Brow. Ophthalmic Plast Reconstr Surg. 2017 Nov/Dec; 33(6):e166-e169.
- Ocular Surface Squamous Neoplasia in a Patient With Hepatitis C. JAMA Ophthalmol. 2017 10 01; 135(10):1121-1123.
- An Unusual Corneal Degeneration. JAMA Ophthalmol. 2017 06 01; 135(6):667-668.
- Ocular surface squamous neoplasia in a patient with AIDS. CMAJ. 2017 05 15; 189(19):E700.
- Orbital Complication Following Calcium Hydroxylapatite Filler Injection. Ophthalmic Plast Reconstr Surg. 2017 May/Jun; 33(3S Suppl 1):S16-S17.
- Clear-Cell (Reticulated) Transformation of Eyelid Eccrine Sweat Glands. Ophthalmic Plast Reconstr Surg. 2017 May/Jun; 33(3):e69-e72.
- Pseudomonas Aeruginosa: A Masquerader in Sino-Orbital Infections. Ophthalmic Plast Reconstr Surg. 2016 Sep-Oct; 32(5):374-7.
- Intraocular Teratoid Medulloepithelioma Presenting With a Completely Rhabdomyosarcomatous Distant Metastasis. JAMA Ophthalmol. 2016 Aug 01; 134(8):919-23.
- Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease: An Analysis of Vascular Growth Factors with Clinical Correlation. Ophthalmology. 2016 09; 123(9):2028-36.
- Vascular Engorgement of Lacrimal Gland Associated With Port-Wine Stain. Ophthalmic Plast Reconstr Surg. 2016 Jul-Aug; 32(4):e92-4.
- An Atypical Ulcerated Lesion at the Eyelid Margin. JAMA Ophthalmol. 2016 06 01; 134(6):703-4.
- Atypical location of primary orbital conjunctival epithelial cysts: a case series. Clin Exp Ophthalmol. 2016 Aug; 44(6):524-6.
- Multicentric myofibromatosis presenting as a large congenital eyelid myofibroma. J AAPOS. 2016 Feb; 20(1):70-3.
- Limbal Mantle Cell Lymphoma of the Conjunctiva. Ophthalmology. 2016 Feb; 123(2):377.
- Nonlimbal Squamous Cell Carcinoma of the Conjunctiva. Ophthalmology. 2016 Feb; 123(2):254.
- Lacrimal gland abscess presenting with preseptal cellulitis depicted on CT. J Ophthalmic Inflamm Infect. 2016 Dec; 6(1):1.
- Radioactive Iodine Therapy and Thyroid Eye Disease From an Ophthalmologist's Perspective. Int Ophthalmol Clin. 2015; 55(4):63-72.
- Reactivation of thyroid associated orbitopathy following trauma with intraorbital foreign body. Orbit. 2015 Feb; 34(1):6-9.
- Epstein-Barr virus-positive polymorphous lymphoplasmacytic infiltrate of the lacrimal glands in a patient with acute lymphoblastic leukemia. JAMA Ophthalmol. 2014 Jul; 132(7):892-4.
- Endoscopic bimanual approach to an intraconal cavernous hemangioma of the orbital apex with vascularized flap reconstruction. Ophthalmic Plast Reconstr Surg. 2014 Jul-Aug; 30(4):e104-6.
- Dacryops in the setting of a Boston type II keratoprosthesis. Ophthalmic Plast Reconstr Surg. 2014 May-Jun; 30(3):e73-5.
- Microdebrider use in orbital surgery. Orbit. 2014 Jun; 33(3):189-92.
- Retrospective review of eyelash number in patients who have undergone full-thickness eyelid resection. Ophthalmic Plast Reconstr Surg. 2014 Jan-Feb; 30(1):1-6.
- The role of genetics in the pathogenesis of periocular cutaneous neoplasms: implications for targeted therapy. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):267-74.
- Gaze-evoked amaurosis from orbital breast carcinoma metastasis. Ophthalmic Plast Reconstr Surg. 2013 Jul-Aug; 29(4):e98-e101.
- A cross-sectional survey of the association between bilateral topical prostaglandin analogue use and ocular adnexal features. PLoS One. 2013; 8(5):e61638.
- Endogenous panophthalmitis with orbital cellulitis secondary to Escherichia coli. Clin Exp Ophthalmol. 2013 Sep-Oct; 41(7):716-8.
- Minimally invasive approaches to eyebrow lifting. Int Ophthalmol Clin. 2013; 53(3):47-57.
- Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3868-73.
- Retinal findings in patients with Alport Syndrome: expanding the clinical spectrum. Br J Ophthalmol. 2009 Dec; 93(12):1606-11.
- Central retinal vein occlusion: a case report and review of the literature. Cases J. 2009 Jun 03; 2:7170.
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