Xiying Guan, Ph.D.

Harvard Medical School

Instructor in Otolaryngology

Massachusetts Eye and Ear


Research Summary

Research Area Affiliations

Research Summary

Dr. Xiying Guan’s research focuses on understanding the structure-function relationship of the middle and inner ear in order to develop novel diagnostics and treatments for otologic diseases. His current study on conductive hyperacusis aims to understand the mechanisms of the disease by conducting experimental measurements and finite-element modeling analysis. Such knowledge will provide the scientific foundation necessary for the development of effective treatment plans for the disease that is debilitating for millions of people.

Select Publications

Intracochlear sound pressure measurements in normal human temporal bones during bone conduction stimulation. Stieger C*, Guan X*, Farahmand RB, Page BF, Merchant JP, Abur D, Nakajima HH. Journal of the Association of Research in Otolaryngology. 2018 Aug 31. *co-first author

Impedances of the inner and middle ear estimated from intracochlear sound pressures in normal human temporal bones. Frear D, Guan X, Stieger C, Rosowski JJ, Nakajima HH. Hearing Research 2018;367:17–31.

PVDF-based piezoelectric microphone for sound detection inside cochlea: Towards totally implantable cochlear implants. Park S, Guan X, Kim Y, Creighton F, Wei E, Kymissis I, Nakajima HH, Olson ES. Trends in Hearing. 2018;22:1–11.

Factors affecting sound energy absorbance in acute otitis media model of chinchilla. Guan X, Gan RZ. Hearing Research. 2017;350:22–31.

Motion of tympanic membrane in guinea pig otitis media model measured by scanning laser Doppler vibrometry. Wang X, Guan X, Pineda M, Gan RZ. Hearing Research. 2016;339:184–194.

View a complete list of publications on pubmed.gov »



2003: BS, Electrical Engineering, China University of Geoscience
2006: MS, Electrical Engineering, China University of Geoscience
2014: PhD, Electrical Engineering, University of Oklahoma

Post-graduate Training

2014–2018: Postdoctoral fellowship, Biomechanics of the ear, Mass. Eye and Ear/Harvard Medical School

Professional Societies

2010–Present: Association for Research in Otolaryngology
2016–Present: Sigma XI Communities

Editorial Roles

Ad hoc reviewer, Hearing Research
Ad hoc reviewer, Ear and Hearing
Ad hoc reviewer, Biomechanics and Modeling in Mechanobiology
Ad hoc reviewer, IEEE Transactions of Biomedical Engineering
Ad hoc reviewer, Journal of the Acoustical Society of America
Ad hoc reviewer, Otolaryngology–Head and Neck Surgery