Jason I. Comander, M.D., Ph.D.

Harvard Medical School

Assistant Professor of Ophthalmology

Massachusetts Eye and Ear

Associate Director, Inherited Retinal Disorders Service
Assistant Scientist

Research Summary

Center/Research Area Affiliations

Research Summary

Dr. Comander’s research interests include understanding the molecular basis of retinal degenerations, such as retinitis pigmentosa, and pursuing therapies for these disorders. He has published studies on the natural history of retinitis pigmentosa and other retinal disorders.  Currently, he developing new techniques to speed characterization of potentially-disease causing DNA variants, testing gene therapy techniques in primates, and is an investigator and surgeon for a number of ongoing clinical trials for patients with inherited retinal disorders.

Select Publications

For a full publication list, please see his CV.

Course of Ocular Function in PRPF31 Retinitis Pigmentosa. Hafler BP, Comander J, Weigel DiFranco C, Place EM, Pierce EA. Semin Ophthalmol. 2016;31(1-2):49-52. 

Efficient In Silico Identification of a Common Insertion in the MAK Gene which Causes Retinitis Pigmentosa. Bujakowska KM, White J, Place E, Consugar M, Comander J. PLoS One. 2015 Nov 11;10(11):e0142614.

Visual Function in Carriers of X-Linked Retinitis Pigmentosa. Comander J, Weigel-DiFranco C, Sandberg MA, Berson EL. Ophthalmology. 2015 Sep;122(9):1899-906.

Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. Mantopoulos D, Murakami Y, Comander J, Thanos A, Roh M, Miller JW, Vavvas DG. PLoS One. 2011; 6(9):e24245.

Diagnostic testing and disease monitoring in birdshot chorioretinopathy. Comander J, Loewenstein J, Sobrin L. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5): 329-36.

View a list of publications on pubmed.gov »



  • 1997: A.B., Harvard College
  • 2005: Ph.D., Experimental Pathology, Harvard Medical School
  • 2006: M.D., Harvard Medical School

Postgraduate Training

  • 2007: Fellowship/Internship, Medicine, Brigham & Women's Hospital
  • 2010: Residency, Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear
  • 2012: Clinical Fellowship, Vitreoretinal Surgery, Massachusetts Eye and Ear

Academic Appointments

  • 2012-present Instructor in Ophthalmology, Harvard Medical School

Professional Memberships

  • 1999-present: Member, Massachusetts Medical Society
  • 1999-present: Member, American Association for the Advancement of Science
  • 1991-1994, 2009-present: Member, Association for Research in Vision and Ophthalmology
  • 2002-2006: Member, National Association for Vascular Biology
  • 2007-present: Member, American Academy of Ophthalmology


  • 1993: Finalist, Presidential Scholars
  • 1997: John Harvard Scholarship
  • 1998: Medical Scientist Training Program Scholarship for M.D./Ph.D. Program at Harvard Medical School
  • 2005: Massachusetts Medical Society Information Technology Award
  • 2009: Attendee, Heed Foundation Retreat for Academic Ophthalmology
  • 2013: Research to Prevent Blindness Career Development Award