Dean M. Cestari,
MD
Massachusetts Eye and Ear
Associate Scientist
Harvard Medical School
Associate Professor of Ophthalmology
dean_cestari@meei.harvard.edu
For investigator inquiries only
About My Research
Center/Research Area Affiliations
Biography
Dr. Cestari focuses on the evaluation and treatment of patients with neuro-ophthalmic disease. He is particularly involved with the medical and surgical treatment of patients with adult strabismus and diplopia. He is also developing an animal model for ischemic optic neuropathy and central retinal artery occlusion, after which he will evaluate the safety and efficacy of various navel neuro-protective agents to preserve and restore vision affected by vascular occlusion.
Education
1987-1992: BA, Colgate University, Hamilton, NY
1994-1992: D. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Postgraduate Training
1998-1999: Intern, Dept. of Internal Medicine, New York Presbyterian Hospital/Cornell University Medical College, New York, NY
1999-2002: Resident in Neurology, New York Presbyterian Hospital/Cornell University Medical College, New York, NY
2002-2003: Fellow in Neuro-Ophthalmology, Massachusetts Eye and Ear Infirmary/Harvard Medical School Boston, MA
2003-2006: Ophthalmology Residency, New York Presbyterian/Cornell University Medical College
2005-2006; Chief Resident in Ophthalmology, New York Presbyterian Hospital/Cornell University Medical College, New York, NY
Academic Appointments
2018: Associate Professor in Ophthalmology, Harvard Medical School
2008: Assistant Professor in Ophthalmology, Harvard Medical School
2006: Instructor in Ophthalmology, Harvard Medical School
2002: Instructor in Ophthalmology, Harvard Medical School
Professional Memberships
2009: Fellow, American Academy of Ophthalmology
2006: North American Neuro-Ophthalmology Society
2003: American Academy of Ophthalmology
1999: American Academy of Neurology
Honors
1990 and 1991: Dean’s Award, Colgate University
1991: National Science Foundation, Research Experience for Undergraduates
2003: Outstanding Teaching and Commitment to Education, Recognized by the Ophthalmology Residency at the Massachusetts Eye and Ear
2006: Certificate of Recognition, New York Presbyterian Hospital, Cornell Medical College
2007: Norman Knight Leadership Development Award, Massachusetts Eye and Ear
2018: A. Clifford Barger Excellence in Mentoring Award, HMS
Publications powered by Harvard Catalyst Profiles
- Traumatic rupture of the inferior rectus muscle: case report and review of the literature. Digit J Ophthalmol. 2023; 29(2):45-49.
- Epigenetic Regulation of Optic Nerve Development, Protection, and Repair. Int J Mol Sci. 2022 Aug 10; 23(16).
- Ophthalmic manifestations of dementing disorders. Curr Opin Ophthalmol. 2021 Nov 01; 32(6):515-520.
- Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography. J Neuroophthalmol. 2022 03 01; 42(1):e430-e433.
- Elevated Intracranial Pressure Associated With Exogenous Hormonal Therapy Used for Gender Affirmation. J Neuroophthalmol. 2021 Jun 01; 41(2):217-223.
- Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study. Eye (Lond). 2022 04; 36(4):818-826.
- Optic nerve sheath meningioma. Curr Opin Ophthalmol. 2020 Nov; 31(6):455-461.
- Orbital disease in neuro-ophthalmology. Curr Opin Ophthalmol. 2020 Nov; 31(6):469-474.
- Optic nerve sheath meningioma. Curr Opin Ophthalmol. 2020 Sep 03.
- Orbital disease in neuro-ophthalmology. Curr Opin Ophthalmol. 2020 Sep 03.
- Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder. Neurology. 2020 07 14; 95(2):e111-e120.
- Episodic Visual Distortions and Stroke-Like Symptoms in a 56-Year-Old Man With Intravascular Lymphoma. J Neuroophthalmol. 2020 06; 40(2):265-270.
- Relapsing Optic Neuropathy and Multiple Cranial Neuropathies in a Middle-aged Woman. JAMA Ophthalmol. 2020 01 01; 138(1):95-96.
- Neuro-ophthalmic manifestations of the phakomatoses. Curr Opin Ophthalmol. 2019 Nov; 30(6):434-442.
- Immune checkpoint inhibitors: what neuro-ophthalmologists need to know. Curr Opin Ophthalmol. 2019 Nov; 30(6):426-433.
- Clinical and radiologic approach to 'typical' versus antibody-related optic neuritis. Curr Opin Ophthalmol. 2019 Nov; 30(6):412-417.
- Surgical Responses and Outcomes of Bilateral Medial Rectus Recession in Esotropia With Spinocerebellar Ataxia. J Pediatr Ophthalmol Strabismus. 2019 Jul 01; 56(4):266-270.
- Spontaneous Superior Ophthalmic Vein Thrombosis in a Transgender Man with Systemic Lupus Erythematosus. LGBT Health. 2019 May/Jun; 6(4):202-204.
- Thyroid eye disease: what is new to know? Curr Opin Ophthalmol. 2018 Nov; 29(6):528-534.
- Imaging in neuro-ophthalmology in the context of value-based care. Curr Opin Ophthalmol. 2018 Nov; 29(6):503-507.
- An update of idiopathic intracranial hypertension. Curr Opin Ophthalmol. 2018 Nov; 29(6):495-502.
- Myelin oligodendrocyte glycoprotein-IgG-associated optic neuritis. Curr Opin Ophthalmol. 2018 Nov; 29(6):508-513.
- Ocular myasthenia gravis: an update on diagnosis and treatment. Curr Opin Ophthalmol. 2018 Nov; 29(6):477-484.
- Vertical rectus muscle recession versus combined vertical and horizontal rectus muscle recession in patients with thyroid eye disease and hypotropia. J AAPOS. 2018 08; 22(4):257-261.
- Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) corresponds to visual function. PLoS One. 2018; 13(6):e0199793.
- Tacrolimus Optic Neuropathy. J Neuroophthalmol. 2018 Jun; 38(2):160-166.
- Neuroimaging diagnostic and monitoring approaches in ophthalmology. Curr Opin Neurol. 2018 Feb; 31(1):66-73.
- Case 2-2018. A 41-Year-Old Woman with Vision Disturbances and Headache. N Engl J Med. 2018 01 18; 378(3):282-289.
- Orbital leiomyosarcoma metastasis presenting prior to diagnosis of the primary tumor. Digit J Ophthalmol. 2017; 23(4):22-26.
- Case 38-2017. A 20-Year-Old Woman with Seizures and Progressive Dystonia. N Engl J Med. 2017 Dec 14; 377(24):2376-2385.
- Focal Capillary Dropout Associated With Optic Disc Drusen Using Optical Coherence Tomographic Angiography. J Neuroophthalmol. 2017 12; 37(4):405-410.
- Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis. Br J Ophthalmol. 2018 08; 102(8):1141-1146.
- Advances in experimental optic nerve regeneration. Curr Opin Ophthalmol. 2017 Nov; 28(6):558-563.
- Congenital anomalies of the optic disc: insights from optical coherence tomography imaging. Curr Opin Ophthalmol. 2017 Nov; 28(6):579-586.
- Diplopia after Cataract Extraction. Semin Ophthalmol. 2018; 33(1):11-16.
- Systematic approaches for reviewing neuro-imaging scans in ophthalmology. Digit J Ophthalmol. 2017; 23(3):50-59.
- A Retrospective Review of Orbital Decompression for Thyroid Orbitopathy with Endoscopic Preservation of the Inferomedial Orbital Bone Strut. Ophthalmic Plast Reconstr Surg. 2017 Sep/Oct; 33(5):334-339.
- Diagnostic genetic testing for patients with bilateral optic neuropathy and comparison of clinical features according to OPA1 mutation status. Mol Vis. 2017; 23:548-560.
- Clinical characteristics and long-term visual outcome of optic neuritis in neuromyelitis optica spectrum disorder: A comparison between Thai and American-Caucasian cohorts. Mult Scler Relat Disord. 2017 Oct; 17:87-91.
- Patterns of visual field changes in thyroid eye disease. Orbit. 2017 Aug; 36(4):201-207.
- Isolated presumed optic nerve gumma, a rare presentation of neurosyphilis. Am J Ophthalmol Case Rep. 2017 Jun; 6:7-10.
- Peripapillary Capillary Dilation in Leber Hereditary Optic Neuropathy Revealed by Optical Coherence Tomographic Angiography. JAMA Ophthalmol. 2016 11 01; 134(11):1332-1334.
- Management of Transient Monocular Vision Loss and Retinal Artery Occlusions. Semin Ophthalmol. 2017; 32(1):125-133.
- Demographic, Systemic, and Ocular Factors Associated with Nonarteritic Anterior Ischemic Optic Neuropathy. Ophthalmology. 2016 12; 123(12):2446-2455.
- Does Nocturnal Hypotension Play a Causal Role in Nonarteritic Anterior Ischemic Optic Neuropathy? J Neuroophthalmol. 2016 09; 36(3):329-33.
- Radiation optic neuropathy and retinopathy with low dose (20 Gy) radiation treatment. Am J Ophthalmol Case Rep. 2016 Oct; 3:50-53.
- Migraine photophobia originating in cone-driven retinal pathways. Brain. 2016 07; 139(Pt 7):1971-86.
- An Experimental Animal Model of Photodynamic Optic Nerve Head Injury (PONHI). Curr Eye Res. 2016 11; 41(11):1498-1506.
- Diagnostic and Therapeutic Challenges. Retina. 2016 Jan; 36(1):216-20.
- Leber Hereditary Optic Neuropathy: Bringing the Lab to the Clinic. Semin Ophthalmol. 2016; 31(1-2):107-16.
- Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): A Review and Update on Animal Models. Semin Ophthalmol. 2016; 31(1-2):99-106.
- Atypical Optic Neuritis. Curr Neurol Neurosci Rep. 2015 Dec; 15(12):76.
- Hypometabolic Lateral Recti Due to Bilateral Cranial Nerve VI Palsy. JAMA Ophthalmol. 2015 Sep; 133(9):e151490.
- Hemorrhage Within the Optic Nerve From a Cavernous Hemangioma of the Optic Disc. J Neuroophthalmol. 2015 Sep; 35(3):277-9.
- Early Diagnosis of Subclinical Interferon Alpha-Associated Optic Neuropathy Using Fluorescein Angiography. J Neuroophthalmol. 2015 Sep; 35(3):280-3.
- A rod-sparing retinopathy in bardet-biedl syndrome. Case Rep Ophthalmol. 2015 Jan-Apr; 6(1):30-3.
- Isolated optic nerve, chiasm, and tract involvement in Bing-Neel Syndrome. J Neuroophthalmol. 2014 Dec; 34(4):340-5.
- Optic neuropathy following retrobulbar injection: a review. Semin Ophthalmol. 2014 Sep-Nov; 29(5-6):434-9.
- Intermittent Horner syndrome in a pediatric patient. J Neuroophthalmol. 2014 Jun; 34(2):149-50.
- Ocular flutter as the presenting sign of lung adenocarcinoma. Digit J Ophthalmol. 2014; 20(1):4-6.
- Autosomal dominant hereditary optic neuropathy (ADOA): a review of the genetics and clinical manifestations of ADOA and ADOA+. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):422-6.
- Deprivation amblyopia and congenital hereditary cataract. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):321-6.
- An update on the genetics of comitant strabismus. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):438-41.
- The use of fourth-generation optical coherence tomography in multiple sclerosis: a review. Semin Ophthalmol. 2012 Sep-Nov; 27(5-6):187-91.
- Neuro-imaging: a review for the general ophthalmologist. Semin Ophthalmol. 2012 Sep-Nov; 27(5-6):192-6.
- Concurrent acute brain infarcts in patients with monocular visual loss. Ann Neurol. 2012 Aug; 72(2):286-93.
- Decreased vision and junctional scotoma from pituicytoma. Case Rep Ophthalmol. 2012 May; 3(2):190-6.
- Isolated bilateral fourth cranial nerve palsies as the presenting sign of hydrocephalus. Case Rep Ophthalmol. 2011 May; 2(2):211-4.
- Subtleties in the histopathology of giant cell arteritis. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5):342-8.
- Neuromyelitis optica: a review. Semin Ophthalmol. 2011 Jul-Sep; 26(4-5):337-41.
- Optic nerve involvement with panuveitis in Sweet syndrome. Ocul Immunol Inflamm. 2011 Jun; 19(3):167-70.
- Orbital involvement in Bing-Neel syndrome. J Neuroophthalmol. 2010 Sep; 30(3):255-9.
- The use of diffusion MRI in ischemic optic neuropathy and optic neuritis. Semin Ophthalmol. 2010 Sep-Nov; 25(5-6):225-32.
- The use of onabotulinum toxin A in the treatment of see-saw nystagmus. J Pediatr Ophthalmol Strabismus. 2010 Jul 22; 47 Online:e1-3.
- Monocular nasal hemianopia from atypical sphenoid wing meningioma. J Neuroophthalmol. 2010 Jun; 30(2):160-3.
- Can't hear, can't see, and too sore to play. Surv Ophthalmol. 2010 May-Jun; 55(3):290-6.
- Giant cell arteritis and angiogenesis: a review. Semin Ophthalmol. 2009 May-Jun; 24(3):190-3.
- Recurrent isolated sixth nerve palsy after consecutive annual influenza vaccinations in a child. J AAPOS. 2009 Jun; 13(3):317-8.
- Diffusion-weighted magnetic resonance imaging of bilateral simultaneous optic nerve infarctions. Arch Neurol. 2009 Jan; 66(1):132-3.
- Case records of the Massachusetts General Hospital. Case 40-2008. A 26-year-old man with blurred vision. N Engl J Med. 2008 Dec 25; 359(26):2825-33.
- Multifocal electroretinographic abnormalities in ethambutol-induced visual loss. J Neuroophthalmol. 2008 Dec; 28(4):278-82.
- Silent sinus syndrome presenting as enophthalmos long after orbital trauma. J Neuroophthalmol. 2008 Jun; 28(2):107-10.
- Leber hereditary optic neuropathy in an octogenarian. J Neuroophthalmol. 2008 Jun; 28(2):156.
- NMO antibody-positive recurrent optic neuritis without clear evidence of transverse myelitis. Arch Ophthalmol. 2008 Apr; 126(4):566-70.
- Neurofibromatosis type I: genetics and clinical manifestations. Semin Ophthalmol. 2008 Jan-Feb; 23(1):45-51.
- The genetics of leber hereditary optic neuropathy--prototype of an inherited optic neuropathy with mitochondrial dysfunction. Semin Ophthalmol. 2008 Jan-Feb; 23(1):27-37.
- Ascertainment of cultural background in patients with giant cell arteritis. Am J Ophthalmol. 2007 Jul; 144(1):164; author reply 164-5.
- Macular star associated with Behçet disease. Retina. 2006 Apr; 26(4):468-70.
- Stroke in patients with cancer: incidence and etiology. Neurology. 2004 Jun 08; 62(11):2025-30.
- The neuroophthalmic manifestations and treatment options of unruptured intracranial aneurysms. Int Ophthalmol Clin. 2004; 44(1):169-87.
- Intracranial hypertension following epidural blood patch. Neurology. 2003 Nov 11; 61(9):1303.
- GABAergic neurons in rat nuclei of solitary tracts receive inhibitory-type synapses from amygdaloid efferents lacking detectable GABA-immunoreactivity. J Neurosci Res. 1996 Jun 01; 44(5):446-58.
- Amygdala efferents form inhibitory-type synapses with a subpopulation of catecholaminergic neurons in the rat Nucleus tractus solitarius. J Comp Neurol. 1995 Nov 27; 362(4):510-23.
- Immunolabeling of retrogradely transported Fluoro-Gold: sensitivity and application to ultrastructural analysis of transmitter-specific mesolimbic circuitry. J Neurosci Methods. 1994 Nov; 55(1):65-78.
- Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain Res. 1994 Jun 06; 647(2):307-22.
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