A full-time member of the Glaucoma Service, Dr. van Zyl specializes in the medical and surgical treatment of glaucoma and cataracts. She sees patients at two Boston locations—Mass. Eye and Ear's main campus on Charles Street and Mass. Eye and Ear Longwood (800 Huntington Avenue).
As the recipient of the NIH K12 clinician scientist career development award, she studies molecular and genetic characteristics that may increase a person's risk of developing glaucoma. Using advanced genomic sequencing technology, Dr. van Zyl works closely with researchers at Mass General Hospital, the Broad Institute of MIT and Harvard, and Harvard Department of Molecular and Cellular biology to study the differences between the cells in healthy and unhealthy (glaucomatous) ocular tissues. She is particularly interested in the trabecular meshwork, a complex structure responsible for regulating pressure inside the eye, often dysfunctional in patients with glaucoma.
Minimally invasive glaucoma surgery (MIGS), including iStent, Kahook Dual Blade, ab interno canaloplasty (ABiC), endoscopic cyclophotocoagulation (ECP), and Xen Gel stent
Steroid-induced glaucoma, Pseudoexfoliation, Trabecular meshwork dysfunction
van Zyl T, Turalba A. Adjunctive Imaging for Canal-based Glaucoma Surgery. Int Ophthalmol Clin. 2017 Fall;57(4):73-84.
Lam JD, Oh DJ, Wong LL, Amarnani D, Park-Windhol C, Sanchez AV, Cardona-Velez J, McGuone D, Stemmer-Rachamimov AO, Eliott D, Bielenberg DR, van Zyl T, Shen L, Gai X, D'Amore PA, Kim LA, Arboleda-Velasquez JF. Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. Diabetes. 2017 Jul;66(7):1950-1956.
Modjtahedi BS, van Zyl T, Pandya HK, Leonard RE 2nd, Eliott D. Endophthalmitis After Intravitreal Injections in Patients With Self-reported Iodine Allergy. Am J Ophthalmol. 2016 Oct;170:68-74.
van Zyl T, Stagner AM, Lee NG. An Atypical Ulcerated Lesion at the Eyelid Margin. JAMA Ophthalmol. 2016 Jun 1;134(6):703-4.
van Zyl, T., Stagner, A. M., Jakobiec, F. A., & Yoon, M. K. Histopathologic features of a resolving orbital Langerhans cell histiocytosis. Graefe's Archive for Clinical and Experimental Ophthalmology. 2015 Dec;253(12):2341-3