A pioneer in both the development and use of lasers to treat skin diseases and disorders, Dr. Oon Tian Tan is the Director of the Carolyn and Peter Lunch Center for Laser and Reconstructive Surgery at Mass. Eye and Ear. She completed medical school at the Royal Free Hospital School of Medicine at London University, where she also completed her surgical internship year and residency in dermatology. Subsequently, she completed fellowship training in dermatology at Mass General Hospital/Harvard Medical School and later received her Ph.D. from the University of Amsterdam.
After spending two decades in private practice, Dr. Tan joined Mass. Eye and Ear in 2010, bringing her wealth of experience in dermatological conditions and treatments. Today, she utilizes an array of lasers to treat birthmarks including hemangioma, portwine stains, and café au lait, as well as other benign cutaneous pigmented lesions, warts, tattoos, and scars.
Throughout her career, Dr. Tan has seen many achievements, including her collaboration on a vascular-specific laser targeting red blood cells and the development of a laser to remove tattoos. She joins annual mission trips to Latin America to care for underserved pediatric patients and was responsible for bringing the first laser to a Quito, Ecuador hospital.
Dr. Tan’s research interests include laser/tissue interaction, imaging systems for differentiation of normal and abnormal tissues, monitoring response of benign cutaneous vascular tumors to laser treatments, evaluation of non-invasive techniques for measuring cutaneous blood flow to be applied to the measurement of vasoactive drug responses in peripheral vascular disease, treatment of facial flushing, hypertrophic scars, and the treatment and prevention of leg ulcers. Her research also focuses on the basic science of vascular anomalies, especially port-wine stains and their aetiology, including their genetic origin.
Quantitative three-dimensional assessment of port-wine stain clearance after laser treatments. Frigerio A, Bhama PK, Tan OT. Lasers Surg Med. 2013 Oct 24.
Mutations in a novel factor, glomulin, are responsible for glomovenous malformations ("glomangiomas"). Brouillard P, Boon LM, Mulliken JB, Enjolras O, Ghassib M, Warman ML, Tan OT, Olsen BR, Vikkula M. American Journal of Human Genetics. 2002. (4); 70:866–874.
RASA 1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation. Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Dsir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente MD, Laut-Labrze C, Delrue MA, Bayliss S, Martorell L, Gonzlez-Ense;at MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M. Human Mutation. 2013 Aug 29.
Removal of colored tattoos with the Q-switched Alexandrite Laser. Stafford TJ, Lizek,R, Boll, J, Tan OT. Plastic and Reconstructive Surgery. 1995. 95:313–320
Treatment of children with port-wine stains using the flashlamp-pulsed tunable dye laser. Tan OT, Sherwood K, Gilchrest BA. New England Journal of Medicine. 1989. 320:416–421.
View a complete list of publications on pubmed.gov »