Shizuo Mukai, M.D.



Ophthalmic Oncology

Board Certification

  • Ophthalmology

Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-3730
Fax: 617-573-3698



Dr. Mukai is a clinician scientist with clinical expertise in the surgical and medical management of vitreoretinal diseases, including complex retinal detachments, pediatric retina, intraocular tumors of the posterior segment (especially retinoblastoma), genetic retinal diseases, and retinal imaging. His research interests include molecular biology of retinal diseases (especially retinoblastoma) and proliferative vitreoretinopathy, new treatment approaches to retinoblastoma, smartphone-based retinal imaging and computerized image analysis, phenotype-genotype correlations in genetic retinal conditions, and retinal stem cells.

Clinical Interests

Medical and surgical management of vitreoretinal diseases, pediatric retina, retinal tumors, genetics of retinal diseases

Research Interests

Retinal stem cells, molecular genetics of retinal diseases, new treatment approaches to retinoblastoma, retinal photography


For a full list of publications, please see his CV.

Haddock LJ, Kim DY, Mukai S. Simple, inexpensive technique for high-quality smartphone fundus photography in human and animal eyesJournal of Ophthalmology 2013, Article ID 518479, 5 pages. 

Mouw KW, Sethi RV, Yeap BY, MacDonald SM, Chen Y-LE, Tarbell NJ, Yock TI, Munzenrider JE, Adams J, Grabowski E, Mukai S, Shih HA. Proton radiation therapy for the treatment of retinoblastoma. Int J Radiation Oncol Biol Phys 2014 Nov 15;90(4):863-9. Epub 2014 Sep 13.

Jakobiec FA, Trief D, Rashid A, Rose MF, Minkler D, Vanderveen D, Mukai S. New insights into the development of infantile intraocular medulloepitheioma. Am J Ophthalmol 2014 Dec;158(6):1275-1296.e1. Epub 2014 Aug 28.

Gupta MP, Talcott KE, Kim DY, Agarwal S, Mukai S Retinal findings and a novel TINF2 mutation in Revesz syndrome: clinical and molecular correlations with pediatric retinal vasculopathiesOphthalmic Genetics 2017; 38(1): 51-60.  

Shen BY, Mukai S.  A portable, inexpensive, non-mydriatic fundus camera based on the Raspberry Pi computer.  Journal of Ophthalmology 2017, Article ID 4526243, 5 pages.  

View a complete list of publications on>>



  • Biology, Brown University, ScB
  • Studio Art, Brown University, AB
  • Brown University School of Medicine, M.D.


  • Ophthalmology, Harvard Medical School


  • Vitreoretinal Surgery, Mass. Eye and Ear