Eric Holbrook, M.D.

Director, Division of Rhinology

Associate Professor of Otolaryngology, Harvard Medical School


Sinus and Nasal Disorders

Endoscopic Skull Base Surgery

Board Certification

  • Otolaryngology-Head and Neck Surgery

Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-3209
Fax: 617-573-6845
call for appointment schedule
Accepting New Patients



Dr. Eric Holbrook, the Chief of the Rhinology Division at Mass. Eye and Ear, is a fellowship-trained rhinologist with more than 15 years of experience in the diagnosis, treatment, and management of problems involving the nose and sinuses. Dr. Holbrook received his master’s degree in Anatomy and Cell Biology and his medical degree from the State University of New York Health Science Center. He completed his residency in otolaryngology at Virginia Commonwealth University-MCV and his fellowship in rhinology/sinus surgery at the University of Nebraska Medical Center. In 2003, Dr. Holbrook joined the medical staff at Mass. Eye and Ear and now, in addition to serving as the Division Chief of Rhinology, is the Associate Director for the Harvard Rhinology and Sinus Surgery Fellowship and an Associate Professor of Otolaryngology at Harvard Medical School.

At Mass. Eye and Ear, Dr. Holbrook was involved in the establishment of the Sinus Center, the Smell and Taste Clinic, and the Endoscopic Skull Base surgery team. Dr. Holbrook has been an invited speaker at national and international meetings and has published more than 35 peer-reviewed papers and several textbook chapters. He has also been named “Best Doctor in Otolaryngology” by Boston Magazine (2017) and Best Doctors, Inc. (2017).

Dr. Holbrook’s clinical interests include diseases of the nose and sinuses, endoscopic approaches to the skull base, and smell and taste disorders. He is a member of the Skull Base Center at Mass. Eye and Ear/Mass General, the Hereditary Hemorrhagic Telangiectasia (HHT) Center at Mass General, and the Center for Thyroid Eye Disease and Orbital Surgery as Mass. Eye and Ear.

His research interests include olfaction and chronic rhinosinusitis. His olfactory research is partly funded by the National Institutes of Health.

Select Publications

An immunochemical, ultrastructural, and developmental characterization of the horizontal basal cells of rat olfactory epithelium. Holbrook EH, Mieleszko Szumowski KE, Schwob JE. J Comp Neurol. 1995. 363:129-46.

Abnormalities of axon growth in human olfactory mucosa. Holbrook EH, Leopold DA, Schwob JE. Laryngoscope. 2005. 115:2144-54.

Immunohistochemical characterization of human olfactory tissue. Holbrook EH, Wu E, Curry WT, Lin DT, Schwob JE. Laryngoscope. 2011. 121:1687-1701.

Proteoglycan abnormalities in olfactory epithelium tissue from subjects diagnosed with schizophrenia. Pantazopoulos H, Boyer-Boiteau A, Holbrook EH, Jang W, Hahn C, Arnold SE, Berretta S. Schizophrenia Research. Schizophr Res. 2013 Nov. 150(2-3):366-72.

View a complete list of publications on »



  • State University of New York, Health Science Center, M.D.


  • State University of New York, Health Science Center (General Surgery)


  • Medical College of Virginia (Otolaryngology)


  • Nebraska Medical Center (Rhinology)