Richard E. Gliklich, M.D.

Director, Clinical Outcomes Research Unit

Leffenfeld Professor of Otolaryngology, Part-time, Harvard Medical School


Facial Plastic and Reconstructive Surgery

Board Certification

  • Otolaryngology-Head and Neck Surgery
  • Facial Plastic and Reconstructive Surgery

Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-4105
Fax: 617-573-3727
Wednesdays from 8am to 4pm



Dr. Richard Gliklich is the Leffenfeld Professor of Otolaryngology at Harvard Medical School who has done foundational work in healthcare outcomes and analytics. As the senior editor of the landmark publication by the U.S. Agency for Healthcare Research and Quality (AHRQ) handbook, Registries for Evaluating Patient Outcomes: A User’s Guide, he has led several key national and international efforts focused on evaluating the safety, effectiveness, value, and quality of healthcare. Some of the programs developed with Dr. Gliklich include the American Heart Association’s Get With The Guidelines SM registries, which received the 2004 Innovation Award from the U.S. Department of Health and Human Services and the 2007 eHealth Initiative Award. 

In addition to his work as a surgeon-scientist, Dr. Gliklich is the CEO and Chairman of OM1 and an XIR at Catalyst. He was previously the President of the Outcome Division of Quintiles, the largest provider of biopharmaceutical development and commercial outsourcing services, and he also served on their executive committee through its 2013 IPO. Prior to Quintiles, Dr. Gliklich was the Founder, CEO, and Chairman of Outcome, a health information and services company that served more than 2,500 healthcare organizations and a majority of the global Top 30 life sciences companies. Dr. Gliklich led Outcome from its start as a spin-off from his Harvard affiliated research laboratory in 1998 through its acquisition by Quintiles in October 2011. 

Dr. Gliklich also holds several patents for both health outcomes systems and medical devices. He is a graduate of Yale University and Harvard Medical School and a former Charles A. Dana Scholar at the University of Pennsylvania.

Select Publications

Survey of real-world research workforce, training, and education report from the DIA Real-World Outcomes Task Force. Gliklich R, Glennie J, Mattox PW, Graff JS, Garner S, Marrone CM, et al. Drug Information Journal. 2012;46:185–191.

Why observational studies should be among the tools used in comparative effectiveness research
. Dreyer NA, Tunis SR, Berger M, Ollendorf D, Mattox P, Gliklich R. Health Aff (Millwood). 2010;29(10):1818–25.

Prepare for the long haul of drug monitoring. Gliklich R. Nat Med. 2010;16(8):848.

GRACE principles: recognizing high-quality observational studies of comparative effectiveness. Dreyer NA, Schneeweiss S, McNeil BJ, Berger ML, Walker AM, Ollendorf DA, Gliklich RE. Am J Manag Care. 2010;16(6):467–71.

Outcomes of fat injection laryngoplasty in unilateral vocal cord paralysis. Fang TJ, Li HY, Gliklich RE, Chen YH, Wang PC, Chuang HF. Arch Otolaryngol Head Neck Surg. 2010;136(5):457–62.

Patient registries. Gliklich R, Campion FX. MGMA Connex. 2010;10(1):15–7.

Epidemiology of bisphosphonate-related osteonecrosis of the jaws: The utility of a national registry. Gliklich RE, Wilson J. J Oral Maxillofac Surg. 2009;67:71–74.

The American Orthopaedic Association's "own the bone" initiative to prevent secondary fractures. Tosi LL, Gliklich R, Kannan K, Koval KJ. J Bone Joint Surg Am. 2008;90(1):163–73.

Impacts of shift-work on sleep quality in a Taiwanese factory. Fu-Jen Journal of Medicine. Hsu SY, Tu YW, Shih TS, Chen NH, Wang PC, Lin Y, Chen CW, Chen CJ, Lin JD, Li HY, Gliklich RE. 2007 Dec;5(4).

Good practices for handling adverse events detected through patient registries
. Dreyer NA, Sheth N, Trontell A, Gliklich RE. DIA Journal. 2008 Aug;5(42):421–428.

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  • Harvard Medical School, M.D.


  • Harvard Medical School (General Surgery)


  • Harvard Medical School (Otolaryngology)


  • Massachusetts Eye and Ear Infirmary (Facial Plastic and Reconstructive Surgery, Microvascular Surgery)