University of Michigan (Biochemistry)
Wayne State University School of Medicine
Wayne State University School of Medicine (PhD in Cancer Biology)
Utilizing radiolabeled 3'-deoxy-3'-[18F]fluorothymidine with positron emission tomography to monitor the effect of dexamethasone on non-small cell lung cancer. McHugh CI, Thipparthi M, Polin L, Lawhorn-Crews JM, Gadgeel S, Akoury J, Patki M, Douglas KA, Mangner TJ, Li J, Matherly LH, Ratnam M, Shields AF. J Nucl Med. 2018 April 19.
Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents: 18F-FAU, 18F-FMAU, and 18F-FLT. McHugh CI, Lawhorn-Crews JM, Douglas KA, Modi D, Jones SK, Mangner TJ, Collins JM, Shields AF. Cancer Imaging. 2016;16(1):34.
Integrating dynamic positron emission tomography and conventional pharmacokinetic studies to delineate plasma and tumor pharmacokinetics of FAU, a prodrug bioactivated by thymidylate synthase. Li J, Kim S, Shields AF, Douglas KA, McHugh CI, Lawhorn-Crews JM, Wu J, Mangner TJ, LoRusso PM. J Clin Pharmacol. 2016;56(11):1433–1447.