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Adeeb Derakhshan, M.D.

Dr. Adeeb Derakhshan portrait

Dr. Adeeb Derakhshan grew up in Charleston, West Virginia and attended West Virginia University for his undergraduate studies. He graduated summa cum laude with a Bachelor degree in chemistry and mathematics. He subsequently matriculated at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. While in medical school, Dr. Derakhshan spent a year as a fellow in the Medical Research Scholars Program at the National Institutes of Health, during which time he investigated targeted therapies for the treatment of head and neck squamous cell carcinoma. 

Dr. Derakhshan has participated in a variety of different types of clinical and basic science research. His primary research interests include the use of precision medicine in cancer patients, nerve regeneration, and surgical outcomes.


Undergraduate School
West Virginia University (Chemistry and Mathematics)

Medical School
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University


Facial nerve sacrifice during parotidectomy: A cautionary tale in pathologic diagnosis. Derakhshan A, Abt NB, Naunheim MR, Osborn HA, Deschler DG. Am J Otolaryngol. 2017;38(3):358–9.

Thoracic duct injury following cervical spine surgery: A multi-center retrospective review. Derakhshan A, Lubelski D, Steinmetz MP, Corriveau M, Lee S, Pace JR, Smith GA, Gokaslan Z, Bydon M, Arnold PM, Fehlings MG, Riew KD, Mroz TE. Global Spine J. 2017;7(1):115S–9S.

Therapeutic small molecules target inhibitor of apoptosis proteins in cancers with deregulation of extrinsic and intrinsic cell death pathways. Derakhshan A, Chen Z, Van Waes C. Clin Cancer Res. 2017;23(6):1379–87.

SMAC mimetic birinapant plus radiation eradicates human head and neck cancers with genomic amplifications of cell death genes FADD and BIRC2. Derakhshan A, Eytan DF, Snow GE, Carlson S, Saleh A, Schiltz S, Cheng H, Mohan S, Cornelius S, Coupar J, Sowers AL, Hernandez L, Mitchell JB, Annunziata CM, Chen Z, Van Waes C. Cancer Res. 2016;76(18):5442–54.

Cost-utility analysis of one and two-level lumbar fusions with and without recombinant human bone morphogenic protein-2. Alvin MD, Derakhshan A, Lubelski D, Abdullah KG, Benzel EC, Mroz TE. Clin Spine Surg. 2016;29(1):E28–33.

Utility of computed tomography imaging following anterior cervical diskectomy and fusion. Derakhshan A, Lubelski D, Steinmetz MP, Benzel EC, Mroz TE. Global Spine J. 2015;5(5):411–6.

The impact of socioeconomic status on the utilization of spinal imaging. Derakhshan A, Miller J, Lubelski D, Nowacki A, Wells B, Milinovich A, Benzel EC, Mroz TE, Steinmetz MP. Neurosurgery. 2015;77(5):746–54. 

The use of cryotherapy for papilloma and early laryngeal cancers: Long-term results. Benninger M, Derakhshan A, Milstein C. Ann Otol Rhinol Laryngol. 2015;124(7):509–14.

The impact of preoperative depression on quality of life outcomes following lumbar surgery. Miller J, Derakhshan A, Lubelski D, Alvin MD, Benzel EC, Mroz TE. Spine J. 2015;15(1):58–64. 

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Joshi P, Jacobs B, Derakhshan A, Moore LR, Elson P, Triozzi P, Borden EC, Zborowski M. Oncotarget. 2014;5(9):2450–61.