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Michael A. Sandberg, Ph.D.

Associate Professor of Ophthalmology

Dr. Sandberg received his B.A. from Brandeis University in Waltham, Mass., in 1969, his M.Sc. from Brown University in Providence, RI in 1972, and his Ph.D. from Brown University in 1974. He has been an investigator in the Berman-Gund Laboratory since 1974, except for a one-year postdoctoral fellowship with Dr. Edgar Auerbach at Hadassah Hospital in Jerusalem, Israel, in 1975.

Dr. Sandberg’s areas of expertise are the psychophysical and electrophysiological assessment of the visual system, physiological and physical optics, data acquisition software, and biostatistics. His accomplishments include the development of a hand-held stimulator-ophthalmoscope for monitoring electrophysiological function within the macula, the implementation of a data acquisition system for detecting submicrovolt full-field electroretinograms in patients with retinitis pigmentosa and other generalized retinal degenerations, and helping to establish that dietary supplementation with vitamin A and omega-3 rich fatty acids slows the course of retinitis pigmentosa. More recently he has been studying the course of cystoid macular edema in retinitis pigmentosa with optical coherence tomography (OCT).

Dr. Sandberg has published more than 100 peer-reviewed articles in ophthalmology journals and several book chapters, mostly concerning retinitis pigmentosa and macular degeneration. He has also served as a reviewer for many ophthalmology journals. He received a Certificate of Appreciation from the Retinitis Pigmentosa Foundation in 1981 and has been principal investigator on several National Eye Institute grants. In addition to his research, for the last 10 years Dr. Sandberg has been performing free community screening for eye disease as a member of the Massachusetts Lions.


Sandberg MA, Brockhurst RJ, Gaudio AR, Berson EL. The association between visual acuity and central retinal thickness in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2005, 46:3349-54.
Pawlyk BS, Smith AJ, Buch PK, Adamian M, Hong D-H, Sandberg MA, Ali RR, Li T. Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP. Invest Ophthalmol Vis Sci. 2005;46:3039-45.
Sandberg MA, Gaudio AR. Reading speed in patients with advanced retinitis pigmentosa or choroideremia. Retina. 2006;26:80-8.
Brockhurst RJ, Sandberg MA. Optical coherence tomography findings in occult macular dystrophy. Am J Ophthalmol. 2007;143:516-8.
Sandberg MA, Rosner B, Weigel-DiFranco C, Dryja TP, Berson EL. Disease course of patients with X-linked retinitis pigmentosa due to RPGR gene mutations. Invest Ophthalmol Vis Sci. 2007;48:1298-304.
A complete list of research publications can be seen at