Kathryn Colby, M.D., Ph.D.

Epidemiology of Atypical Keratitis

Over the last 5 years there has been and increase in corneal infections caused by unusual organisms, especially in contact lens wearers.  These organisms include fungi and Acanthamoeba.  Both types of organisms can cause severe cornea infections that result in devastating vision loss.  This study examines the factors that contribute to the risk of infection as well as outcomes following these infections.

Investigation of the Role of Human Tears in the Protection against Acanthamoeba Keratitis

In this study, tears are collected from patients with confirmed Acanthamoeba keratitis and normal controls to characterize substances in the tears that may predispose to or protect from this infection.  This study is performed in collaboration with basic science researchers at Tufts University.