Clint L. Makino, Ph.D.
Associate Professor of Ophthalmology, Department of Ophthalmology
Dr. Makino studies the molecular mechanisms of visual transduction. He discovered that some retinal cones express mixtures of visual pigments, that the expression level of rhodopsin impacts rod outer segment structure, and that light activation of rhodopsin can be mimicked by the binding of vitamin A. Most recently, he has started testing the idea that there are nonretinoid compounds that bind to opsin / rhodopsin and modulate its activity.