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Patricia A D'Amore, Ph.D., MBA

Harvard Medical School

Charles L. Schepens Professor of Ophthalmology, Department of Ophthalmology
Co-Director, AMD Center of Excellence
Vice Chair for Basic Research

Massachusetts Eye and Ear/Schepens Eye Research Institute

Director of Research, Schepens Eye Research Institute
Senior Scientist

Center Affiliations

Research Summary

Dr. D'Amore has contributed to the development of anti-angiogenic therapies for common neovascular eye diseases. Currently, she is working on five major projects in her laboratory: 1) the role of Notch signaling in the function and integrity of the adult retinal vasculature; 2) the role of vascular endothelial growth factor in the adult,which has important implications for wet age-related macular degeneration (AMD); 3) the role of the pericyte in vessel integrity and stability in the adult, and the relevance of pericyte loss to the pathogenesis of AMD; 4) the role of inflammasome-mediated RPE damage and inflammation in AMD; and 5) the role of endomucin in the regulation of angiogenesis and endothelial-leukocyte interactions.

Photo of Patricia A D'Amore, Ph.D., MBA

Patricia A D'Amore, Ph.D., MBA


Schepens Eye Research Institute

20 Staniford Street

Boston, MA 02114

T: 617-912-2559

F: 617-912-0128