Ocular Oncology


Centers of Excellence Center of Excellence

ocular oncology

Harvard Medical School Department of Ophthalmology


CO-DIRECTORS
Kathryn A. Colby, M.D., Ph.D.
Bruce R. Ksander, Ph.D.

Ocular oncology involves the study and treatment of tumors that occur in or around the eye. These tumors may cause vision loss or loss of the eye itself; some tumors are potentially fatal, while others may be benign yet severely disfiguring. Researchers at Mass. Eye and Ear have made groundbreaking advances in the field of ocular oncology. These include the identification and isolation of the retinoblastoma (Rb) gene, the first known tumor-suppressor gene, which formed an important cornerstone in the molecular basis of cancer. Our department is also credited with the development of proton beam irradiation, the gold standard of treatment for uveal melanoma. Ongoing research efforts include studies of cancer susceptibility genes and biomarkers, innovative surgical techniques for ocular malignacies, and developing new therapeutic strategies for retinoblastoma and other ocular cancers.