Oon Tian Tan, M.D., Ph.D.

Harvard Medical School

Lecturer on Otolaryngology, Part-time

Massachusetts Eye and Ear

Director, Carolyn and Peter Lynch Center for Laser and Reconstructive Surgery

Research Summary

Research Area Affiliations

Research Summary

Dr. Tan’s current research interests include laser/tissue interaction, imaging systems for differentiation of normal and abnormal tissues, monitoring response of benign cutaneous vascular tumors to laser treatments, evaluation of non-invasive techniques for measuring cutaneous blood flow to be applied to the measurement of vasoactive drug responses in peripheral vascular disease, treatment of facial flushing, hypertrophic scars, and the treatment and prevention of leg ulcers. Her research also focuses on the basic science of vascular anomalies, especially port-wine stains and their aetiology, including their genetic origin.

Select Publications

Frigerio A, Bhama PK and Tan OT. Quantitative three-dimensional assessment of port-wine stain clearance after laser treatments. Lasers Surg. Med. 2013 Oct 24. doi: 10.1002/lsm.22193

Brouillard P, Boon LM, Mulliken JB, Enjolras O, Ghassibé M, Warman ML, Tan OT, Olsen BR, Vikkula M. Mutations in a novel factor, glomulin, are responsible for glomovenous malformations (“glomangiomas”). American Journal of Human Genetics 2002(4); 70:866-874.

Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Désir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente MD, Léauté-Labrèze C, Delrue MA, Bayliss S, Martorell L, González-Enseñat MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M. RASA 1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation. Human Mutation 2013 Aug 29. doi: 10.1002/humu.22431.

Stafford TJ, Lizek,R, Boll, J, Tan OT.  Removal of colored tattoos with the Q-switched Alexandrite Laser. Plastic and Reconstructive Surgery, 1995;95:313-320

Tan OT, Sherwood K, Gilchrest BA. Treatment of children with port-wine stains using the flashlamp-pulsed tunable dye laser. New England Journal of Medicine 1989; 320:416-421.

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M.D. Royal Free Hospital School of Medicine, London University, 1968
Ph.D. University of Amsterdam, 1993

Postgraduate Training

Internship:  General Surgery, Royal Free Hospital, London, UK
Internship:  Internal Medicine, Royal Free Hospital, London, UK
Residency:  Dermatology, Royal Free Hospital, London
Residency:  Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Fellowship: Wellman Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Professional Memberships

1984- pres    American Academy of Dermatology
1987- pres    International Society for Lasers in Medicine & Surgery
1989- pres    American Society for Dermatologic Surgery, Inc.

Advisory Boards

1988- pres    Medical Advisory:  Sturge-Weber Foundation

Awards and Honors

1988        Medical Instrumentation Award for excellence in communication for paper: Treatment of Portwine Stain at 577nm:  Clinical results.  Presented by the Association for the Advancement of Medical Instrumentation
1987        Whittaker Health Sciences Award
1986        Whittaker Health Science Award
1984        The Dermatology Foundation Fellowship Award by the Dermatology Foundation
1983    Mary Kay Cosmetics Fellowship/Dermatology Foundation Fellowship