Joseph B. Nadol, Jr.,
MD
Massachusetts Eye and Ear
Director Emeritus, Otopathology Laboratory
Senior Scientist
Harvard Medical School
Professor of Otolaryngology–Head and Neck Surgery
About My Research
Dr. Joseph Nadol’s current research focus is the histopathology of the human temporal bone, including those from patients who, in life, had undergone cochlear implantation.
He is interested in anatomic correlates of word recognition and evaluation of damage done to the cochlea and spiral ganglion during implantation and the biologic response, including new bone formation and cellular infiltrates.
To date, more than 70 specimens with a detailed clinical history of deafness and implantation results have been collected. The principal methods used include semi-serial two-dimensional and three-dimensional reconstruction of the inner ear by computer-assisted methods.
Education
BA, Harvard College
MD, Johns Hopkins School of Medicine
Postgraduate Training
Internship, General Surgery, Beth Israel Hospital, Boston
Residency, Otolaryngology, Mass. Eye and Ear/Harvard Medical School
Professional Societies
President, Association for Research in Otolaryngology
President, American Otological Society
Advisory Boards
Advisory Council, NIDCD, NIH
Honors
Claude Pepper Award for Excellence in Research, National Institutes of Health
Distinguished Alumnus Award, Johns Hopkins University School of Medicine
Shambaugh Prize in Otology, Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum
Recognition as “Compassionate Caregiver” by The Schwartz Center
Award of Merit, American Otological Society
Paparella (IHF) Award for Distinguished Contributions in Clinical Otology, American Academy of Otolaryngology–Head and Neck Surgery Foundation
Publications powered by Harvard Catalyst Profiles
- Human Histology after Structure Preservation Cochlear Implantation via Round Window Insertion. Laryngoscope. 2024 Feb; 134(2):945-953.
- Radiological feature heterogeneity supports etiological diversity among patient groups in Meniere's disease. Sci Rep. 2023 06 26; 13(1):10303.
- Three-dimensional quantification of fibrosis and ossification after cochlear implantation via virtual re-sectioning: Potential implications for residual hearing. Hear Res. 2023 02; 428:108681.
- Temporal Bone Histopathology of Undiagnosed Dizziness in the Elderly. Audiol Neurootol. 2023; 28(2):94-105.
- Otopathologic and Computed Tomography Correlation of Internal Auditory Canal Diverticula in Otosclerosis. Otol Neurotol. 2022 10 01; 43(9):e957-e962.
- Computed Tomography Density as a Bio-marker for Histologic Grade of Otosclerosis: A Human Temporal Bone Pathology Study. Otol Neurotol. 2022 07 01; 43(6):e605-e612.
- Cochlear implants: Causes, effects and mitigation strategies for the foreign body response and inflammation. Hear Res. 2022 09 01; 422:108536.
- Intracochlear New Fibro-Ossification and Neuronal Degeneration Following Cochlear Implant Electrode Translocation: Long-Term Histopathological Findings in Humans. Otol Neurotol. 2022 02 01; 43(2):e153-e164.
- Prevalence of Macrophages Within the Cochlear Vessels Following Cochlear Implantation in the Human: An Immunohistopathological Study Using Anti-Iba1 Antibody. Otol Neurotol. 2021 12 01; 42(10):e1470-e1477.
- The Pathology of the Vestibular System in CANVAS. Otol Neurotol. 2021 03 01; 42(3):e332-e340.
- Absence of Endolymphatic Sac Ion Transport Proteins in Large Vestibular Aqueduct Syndrome-A Human Temporal Bone Study. Otol Neurotol. 2020 12; 41(10):e1256-e1263.
- Long-term cochlear implantation outcomes in patients following head injury. Laryngoscope Investig Otolaryngol. 2020 Jun; 5(3):485-496.
- Invasion Patterns of External Auditory Canal Squamous Cell Carcinoma: A Histopathology Study. Laryngoscope. 2021 02; 131(2):E590-E597.
- Labyrinthine concussion: Historic otopathologic antecedents of a challenging diagnosis. Laryngoscope Investig Otolaryngol. 2020 Apr; 5(2):267-277.
- Anatomy of the Human Osseous Spiral Lamina and Cochlear Partition Bridge: Relevance for Cochlear Partition Motion. J Assoc Res Otolaryngol. 2020 04; 21(2):171-182.
- The Distribution and Prevalence of Macrophages in the Cochlea Following Cochlear Implantation in the Human: An Immunohistochemical Study Using Anti-Iba1 Antibody. Otol Neurotol. 2020 03; 41(3):e304-e316.
- Are Cochlear Implants a Viable Option Following Temporal Bone Fracture? Laryngoscope. 2020 07; 130(7):1613-1615.
- Histopathological changes to the peripheral vestibular system following meningitic labyrinthitis. Laryngoscope Investig Otolaryngol. 2020 Apr; 5(2):256-266.
- Otopathology in CHARGE syndrome. Laryngoscope Investig Otolaryngol. 2020 Feb; 5(1):157-162.
- Temporal bone histopathology in MELAS syndrome. Laryngoscope Investig Otolaryngol. 2020 Feb; 5(1):152-156.
- Contemporary techniques in human otopathology and promise for the future. Laryngoscope Investig Otolaryngol. 2020 Feb; 5(1):145-151.
- Temporal bone histopathology: Superior semicircular canal dehiscence. Laryngoscope Investig Otolaryngol. 2020 Feb; 5(1):117-121.
- Density of Macrophages Immunostained With Anti-iba1 Antibody in the Vestibular Endorgans After Cochlear Implantation in the Human. Otol Neurotol. 2019 09; 40(8):e774-e781.
- Abnormal Tectorial Membranes in Sensorineural Hearing Loss: A Human Temporal Bone Study. Otol Neurotol. 2019 08; 40(7):e732-e738.
- Histological characteristics of intra-temporal facial nerve paralysis in temporal bone malignancies. Laryngoscope. 2020 05; 130(5):E358-E367.
- Otopathology Findings in Otosclerosis With Lateral Semicircular Canal Fenestration. Laryngoscope Investig Otolaryngol. 2019 Aug; 4(4):425-428.
- Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease-A Correlative Histology and Computed Tomography Study. Otol Neurotol. 2019 06; 40(5):e548-e555.
- Human Otopathology of Cochlear Implant Drill-out Procedures. Otolaryngol Head Neck Surg. 2019 10; 161(4):658-665.
- Clinical Imaging Findings of Vestibular Aqueduct Trauma in a Patient With Posttraumatic Meniere's Syndrome. Front Neurol. 2019; 10:431.
- Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease-A Correlative Histology and Computed Tomography Study. Otol Neurotol. 2019 Apr 12.
- Sensorineural Hearing Loss in Leukemia: A Case Report Showing Intravascular Coagulation in the Cochlea and Vestibular Labyrinth. Ann Otol Rhinol Laryngol. 2019 Aug; 128(8):689-695.
- Mechanical Compression of Coverslipped Tissue Sections During Heat-induced Antigen Retrieval Prevents Section Detachment and Preserves Tissue Morphology. J Histochem Cytochem. 2019 06; 67(6):441-452.
- Histopathology of the Inner Ear in Charcot-Marie-Tooth Syndrome Caused by a Missense Variant (p.Thr65Ala) in the MPZ Gene. Audiol Neurootol. 2018; 23(6):326-334.
- Vestibular Traumatic Neuroma Following Temporal Bone Fracture. Otol Neurotol. 2019 01; 40(1):e62-e65.
- Otopathology of Unilateral Cochlear Implantation in Patients With Bilateral Temporal Bone Fracture. Otol Neurotol. 2019 01; 40(1):e14-e19.
- Otopathology in Angiosarcoma of the Temporal Bone. Laryngoscope. 2019 03; 129(3):737-742.
- Arachnoid cysts of the internal auditory canal: An underappreciated entity? Laryngoscope. 2019 07; 129(7):1667-1674.
- Focal Degeneration of Vestibular Neuroepithelium in the Cristae Ampullares of Three Human Subjects. Otol Neurotol. 2018 12; 39(10):e1100-e1110.
- Quantitative assessment of vestibular otopathology in granulomatosis with polyangitis: A temporal bone study. Laryngoscope Investig Otolaryngol. 2018 Dec; 3(6):473-477.
- Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture. Otolaryngol Head Neck Surg. 2019 01; 160(1):122-130.
- Human Otopathologic Findings in Cases of Folded Cochlear Implant Electrodes. Otol Neurotol. 2018 09; 39(8):970-978.
- Temporal Bone Histopathology of X-linked Inherited Alport Syndrome. Laryngoscope Investig Otolaryngol. 2018 Aug; 3(4):311-314.
- Otopathologic Changes in the Cochlea following Head Injury without Temporal Bone Fracture. Otolaryngol Head Neck Surg. 2018 09; 159(3):526-534.
- Temporal Bone Histopathology in Cockayne Syndrome. Otol Neurotol. 2018 06; 39(5):e387-e391.
- Preservation of Cells of the Organ of Corti and Innervating Dendritic Processes Following Cochlear Implantation in the Human: An Immunohistochemical Study. Otol Neurotol. 2018 03; 39(3):284-293.
- Evidence of Osteoclastic Activity in the Human Temporal Bone. Audiol Neurootol. 2017; 22(4-5):218-225.
- Temporal bone histopathology of furosemide ototoxicity. Laryngoscope Investig Otolaryngol. 2017 10; 2(5):204-207.
- Correlation of CT and Histopathology in Resorption of the Distal Long Process of the Incus. Clin Neuroradiol. 2018 06; 28(2):293-296.
- Histopathology of the Human Inner Ear in the Cogan Syndrome with Cochlear Implantation. Audiol Neurootol. 2017; 22(2):116-123.
- Foreign Body Response to Silicone in Cochlear Implant Electrodes in the Human. Otol Neurotol. 2017 08; 38(7):970-977.
- Human Cochlear Histopathology Reflects Clinical Signatures of Primary Neural Degeneration. Sci Rep. 2017 07 07; 7(1):4884.
- The pattern and degree of capsular fibrous sheaths surrounding cochlear electrode arrays. Hear Res. 2017 05; 348:44-53.
- Focal Endolymphatic Hydrops as Seen in the Pars Inferior of the Human Inner Ear. Otol Neurotol. 2016 08; 37(7):859-64.
- Cochlear Histopathology as Observed in Two Patients With a Cochlear Implant Electrode With Positioner. Otol Neurotol. 2016 07; 37(6):642-6.
- Correlation between word recognition score and intracochlear new bone and fibrous tissue after cochlear implantation in the human. Hear Res. 2016 09; 339:132-41.
- Lack of Evidence for Nonotosclerotic Stapes Fixation in Human Temporal Bone Histopathology. Otol Neurotol. 2016 Apr; 37(4):316-20.
- Histopathology of the Human Inner Ear in the p.L114P COCH Mutation (DFNA9). Audiol Neurootol. 2016; 21(2):88-97.
- Anti CD163+, Iba1+, and CD68+ Cells in the Adult Human Inner Ear: Normal Distribution of an Unappreciated Class of Macrophages/Microglia and Implications for Inflammatory Otopathology in Humans. Otol Neurotol. 2016 Jan; 37(1):99-108.
- Histopathology of the Human Inner Ear in a Patient With Sensorineural Hearing Loss Caused by a Variant in DFNA5. Otol Neurotol. 2015 Dec; 36(10):1616-21.
- Otopathology of Vasculitis in Granulomatosis With Polyangitis. Otol Neurotol. 2015 Dec; 36(10):1657-62.
- Temporal Bone Histopathology in NOG-Symphalangism Spectrum Disorder. Otol Neurotol. 2015 Dec; 36(10):1651-6.
- Delayed loss of hearing after hearing preservation cochlear implantation: Human temporal bone pathology and implications for etiology. Hear Res. 2016 Mar; 333:225-234.
- Histopathology of the Inner Ear in a Case With Recent Onset of Cogan's Syndrome: Evidence for Vasculitis. Ann Otol Rhinol Laryngol. 2016 Jan; 125(1):20-4.
- Histopathology of the human inner ear in Alström's syndrome. Audiol Neurootol. 2015; 20(4):267-72.
- Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2. J Med Genet. 2015 Aug; 52(8):557-62.
- Cellular immunologic responses to cochlear implantation in the human. Hear Res. 2014 Dec; 318:11-7.
- Intracochlear inflammatory response to cochlear implant electrodes in humans. Otol Neurotol. 2014 Oct; 35(9):1545-51.
- Within-subject comparison of word recognition and spiral ganglion cell count in bilateral cochlear implant recipients. Otol Neurotol. 2014 Sep; 35(8):1446-50.
- Correlation between histologic and radiographic reconstruction of intracochlear electrode position in human temporal bones. Audiol Neurootol. 2014; 19(3):184-92.
- The pathologic basis of facial nerve stimulation in otosclerosis and multi-channel cochlear implantation. Otol Neurotol. 2013 Dec; 34(9):1603-9.
- Histopathology of the inner ear in patients with xeroderma pigmentosum and neurologic degeneration. Otol Neurotol. 2013 Sep; 34(7):1230-6.
- Otopathology in congenital toxoplasmosis. Otol Neurotol. 2013 Aug; 34(6):1165-9.
- Otopathology in idiopathic Dandy's syndrome. Otol Neurotol. 2013 Aug; 34(6):1099-103.
- Histopathology of the Clarion cochlear implant electrode positioner in a human subject. Audiol Neurootol. 2013; 18(4):223-7.
- Effect of monopolar and bipolar electric stimulation on survival and size of human spiral ganglion cells as studied by postmortem histopathology. Hear Res. 2013 Aug; 302:9-16.
- Auditory analysis of xeroderma pigmentosum 1971-2012: hearing function, sun sensitivity and DNA repair predict neurological degeneration. Brain. 2013 Jan; 136(Pt 1):194-208.
- Interaural comparison of spiral ganglion cell counts in profound deafness. Hear Res. 2011 Dec; 282(1-2):56-62.
- Temporal bone histopathology in a case of sensorineural hearing loss caused by superficial siderosis of the central nervous system and treated by cochlear implantation. Otol Neurotol. 2011 Jul; 32(5):748-55.
- The histopathology of revision cochlear implantation. Audiol Neurootol. 2011; 16(5):336-46.
- Factors associated with incomplete insertion of electrodes in cochlear implant surgery: a histopathologic study. Audiol Neurootol. 2011; 16(2):69-81.
- Depth of electrode insertion and postoperative performance in humans with cochlear implants: a histopathologic study. Audiol Neurootol. 2010; 15(5):323-31.
- Genetic determinants of hearing loss associated with vestibular schwannomas. Otol Neurotol. 2009 Aug; 30(5):661-7.
- Foreign body or hypersensitivity granuloma of the inner ear after cochlear implantation: one possible cause of a soft failure? Otol Neurotol. 2008 Dec; 29(8):1076-84.
- Reciprocal synapses between outer hair cells and their afferent terminals: evidence for a local neural network in the mammalian cochlea. J Assoc Res Otolaryngol. 2008 Dec; 9(4):477-89.
- Human temporal bone consortium for research resource enhancement. Otol Neurotol. 2008 Apr; 29(3):271-4.
- Human temporal bone consortium for research resource enhancement. J Assoc Res Otolaryngol. 2008 Mar; 9(1):1-4.
- Analysis of intracochlear new bone and fibrous tissue formation in human subjects with cochlear implants. Ann Otol Rhinol Laryngol. 2007 Oct; 116(10):731-8.
- Anatomy of the round window and hook region of the cochlea with implications for cochlear implantation and other endocochlear surgical procedures. Otol Neurotol. 2007 Aug; 28(5):641-8.
- Otopathology in Mohr-Tranebjaerg syndrome. Laryngoscope. 2007 Jul; 117(7):1202-8.
- Clinical investigation and mechanism of air-bone gaps in large vestibular aqueduct syndrome. Ann Otol Rhinol Laryngol. 2007 Jul; 116(7):532-41.
- Quantitative evaluation of new bone and fibrous tissue in the cochlea following cochlear implantation in the human. Audiol Neurootol. 2007; 12(5):277-84.
- Cochleosaccular dysplasia associated with a connexin 26 mutation in keratitis-ichthyosis-deafness syndrome. Laryngoscope. 2006 Aug; 116(8):1404-8.
- The widely patent cochleovestibular communication of Edward Cock is a distinct inner ear malformation: implications for cochlear implantation. Ann Otol Rhinol Laryngol. 2006 Aug; 115(8):595-606.
- Revision mastoidectomy. Otolaryngol Clin North Am. 2006 Aug; 39(4):723-40, vi-vii.
- Results after revision stapedectomy with malleus grip prosthesis. Ann Otol Rhinol Laryngol. 2006 Apr; 115(4):317-22.
- Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction. Hum Mol Genet. 2006 Apr 01; 15(7):1071-85.
- Histopathology of the inner ear relevant to cochlear implantation. Adv Otorhinolaryngol. 2006; 64:31-49.
- Histopathology of the peripheral vestibular system after cochlear implantation in the human. Otol Neurotol. 2006 Jan; 27(1):57-64.
- Efficient method for the proteomic analysis of fixed and embedded tissues. J Proteome Res. 2005 Nov-Dec; 4(6):2404-11.
- Carcinoid tumor of the middle ear: clinical features, recurrences, and metastases. Laryngoscope. 2005 Sep; 115(9):1660-6.
- Histopathology of human cochlear implants: correlation of psychophysical and anatomical measures. Hear Res. 2005 Jul; 205(1-2):83-93.
- Effect of cochlear implantation on residual spiral ganglion cell count as determined by comparison with the contralateral nonimplanted inner ear in humans. Ann Otol Rhinol Laryngol. 2005 May; 114(5):381-5.
- Is word recognition correlated with the number of surviving spiral ganglion cells and electrode insertion depth in human subjects with cochlear implants? Laryngoscope. 2005 Apr; 115(4):672-7.
- Pathology and pathophysiology of idiopathic sudden sensorineural hearing loss. Otol Neurotol. 2005 Mar; 26(2):151-60.
- Pathophysiology of Meniere's syndrome: are symptoms caused by endolymphatic hydrops? Otol Neurotol. 2005 Jan; 26(1):74-81.
- Temporal bone histopathology in alport syndrome. Laryngoscope. 2004 Sep; 114(9):1609-18.
- Histologic evaluation of the tissue seal and biologic response around cochlear implant electrodes in the human. Otol Neurotol. 2004 May; 25(3):257-62.
- William W. Montgomery, MD, 1923-2003. Ann Otol Rhinol Laryngol. 2004 Jan; 113(1):1-4.
- Axial mesodermal dysplasia sequence: autopsy findings. Clin Dysmorphol. 2004 Jan; 13(1):21-4.
- Obituary: William W. Montgomery, MD. Laryngoscope. 2003 Dec; 113(12):2228-9.
- Histopathology of the inner ear in unoperated acoustic neuroma. Ann Otol Rhinol Laryngol. 2003 Nov; 112(11):979-86.
- Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery. 2003 Sep; 53(3):577-86; discussion 586-8.
- Morphometric changes in the cochlear nucleus in patients who had undergone cochlear implantation for bilateral profound deafness. Hear Res. 2002 Dec; 174(1-2):196-205.
- Malleus fixation: clinical and histopathologic findings. Ann Otol Rhinol Laryngol. 2002 Mar; 111(3 Pt 1):246-54.
- Reciprocal innervation of outer hair cells in a human infant. J Assoc Res Otolaryngol. 2002 Sep; 3(3):269-78.
- Axodendritic and dendrodendritic synapses within outer spiral bundles in a human. Hear Res. 2002 Feb; 164(1-2):97-104.
- Morphometric analysis of age-related changes in the human basilar membrane. Ann Otol Rhinol Laryngol. 2001 Dec; 110(12):1147-53.
- Histopathology and molecular genetics of hearing loss in the human. Int J Pediatr Otorhinolaryngol. 2001 Oct 19; 61(1):1-15.
- Histopathology of cochlear implants in humans. Ann Otol Rhinol Laryngol. 2001 Sep; 110(9):883-91.
- Otopathology in a case of type I Waardenburg's syndrome. Ann Otol Rhinol Laryngol. 2001 Sep; 110(9):875-82.
- Temporal bone histopathologic and genetic studies in Mohr-Tranebjaerg syndrome (DFN-1). Otol Neurotol. 2001 Jul; 22(4):506-11.
- Histologic studies of the posterior stapediovestibular joint in otosclerosis. Otol Neurotol. 2001 May; 22(3):305-10.
- Histopathology of residual and recurrent conductive hearing loss after stapedectomy. Otol Neurotol. 2001 Mar; 22(2):162-9.
- Prevalence and ultrastructural morphology of axosomatic synapses on spiral ganglion cells in humans of different ages. Hear Res. 2000 Dec; 150(1-2):119-31.
- Beyond hearing aids. Health News. 2000 12; 6(12):5.
- Histopathologic features of the temporal bone in usher syndrome type I. Arch Otolaryngol Head Neck Surg. 2000 Aug; 126(8):1018-23.
- Hearing preservation in acoustic neuroma surgery: middle fossa versus retrosigmoid approach. Am J Otol. 2000 May; 21(3):399-404.
- Pattern of degeneration of the spiral ganglion cell and its processes in the C57BL/6J mouse. Hear Res. 2000 Mar; 141(1-2):12-8.
- Outcomes assessment for chronic otitis media: the Chronic Ear Survey. Laryngoscope. 2000 Mar; 110(3 Pt 3):32-5.
- Validation of outcomes survey for adults with chronic suppurative otitis media. Ann Otol Rhinol Laryngol. 2000 Mar; 109(3):249-54.
- Histopathology of cochlear implants. Adv Otorhinolaryngol. 2000; 57:1-6.
- Histopathology of the inner ear in DFNA9. Adv Otorhinolaryngol. 2000; 56:212-7.
- Osteomyelitis, lateral sinus thrombosis, and temporal lobe infarction caused by infection of a percutaneous cochlear implant. Am J Otol. 1999 Nov; 20(6):726-8.
- Training the physician-scholar in otolaryngology-head and neck surgery. Otolaryngol Head Neck Surg. 1999 Sep; 121(3):214-9.
- Standardized format for depicting hearing preservation results in the management of acoustic neuroma. Otolaryngol Head Neck Surg. 1999 Sep; 121(3):176-9.
- Delayed intracranial abscess after acoustic neuroma surgery: a report of two cases. Am J Otol. 1999 May; 20(3):369-72.
- Does otosclerosis occur only in the temporal bone? Am J Otol. 1999 Mar; 20(2):162-5.
- Pathology case of the month: otosclerosis of the cochlear capsule: correlation of computerized tomography and histopathology. Am J Otol. 1999 Jan; 20(1):93-5.
- Prevention of hearing loss in experimental pneumococcal meningitis by administration of dexamethasone and ketorolac. J Infect Dis. 1999 Jan; 179(1):264-8.
- Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nat Genet. 1998 Nov; 20(3):299-303.
- Correlation of acoustic threshold measures and spiral ganglion cell survival in severe to profound sensorineural hearing loss: implications for cochlear implantation. Ann Otol Rhinol Laryngol. 1998 Nov; 107(11 Pt 1):906-11.
- Dense innervation of Deiters' and Hensen's cells persists after chronic deefferentation of guinea pig cochleas. J Comp Neurol. 1998 Oct 26; 400(3):299-309.
- Vertigo produced by petrous extension of a radiation-induced fibrosarcoma of the anterior skull base. Ann Otol Rhinol Laryngol. 1998 Oct; 107(10 Pt 1):898-900.
- A hairy polyp presenting as a middle ear mass in a pediatric patient. Am J Otolaryngol. 1998 Jul-Aug; 19(4):228-31.
- Single-channel to multichannel conversions in adult cochlear implant subjects. Am J Otol. 1998 Jul; 19(4):461-6.
- Nucleus 22 cochlear implantation results in postmeningitic deafness. Laryngoscope. 1997 Dec; 107(12 Pt 1):1606-9.
- Revision stapedectomy: intraoperative findings, results, and review of the literature. Laryngoscope. 1997 Sep; 107(9):1185-92.
- Patterns of neural degeneration in the human cochlea and auditory nerve: implications for cochlear implantation. Otolaryngol Head Neck Surg. 1997 Sep; 117(3 Pt 1):220-8.
- Efficacy of tympanomastoid surgery for control of infection in active chronic otitis media. Laryngoscope. 1997 Jul; 107(7):872-7.
- Morphologic evidence for innervation of Deiters' and Hensen's cells in the guinea pig. Hear Res. 1997 Jun; 108(1-2):74-82.
- Harold Frederick Schuknecht. 1917-1996. Audiol Neurootol. 1997 May-Jun; 2(3):168-70.
- Harold Frederick Schuknecht, M.D. 1917-1996. J Laryngol Otol. 1997 Jan; 111(1):1-3.
- Harold F. Schuknecht, MD. 1917-1996. ORL J Otorhinolaryngol Relat Spec. 1997 Jan-Feb; 59(1):1-3.
- Harold F. Schuknecht 1917-1996. Ann Otol Rhinol Laryngol. 1997 Jan; 106(1):1-4.
- Harold F. Schuknecht, MD, remembered. Laryngoscope. 1996 Dec; 106(12 Pt 1):13a-14a.
- Schuknecht: Presbycusis. (Laryngoscope. 1955;65:402-419). Laryngoscope. 1996 Nov; 106(11):1327-9.
- Techniques for human temporal bone removal: information for the scientific community. Otolaryngol Head Neck Surg. 1996 Oct; 115(4):298-305.
- A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13. Hum Mol Genet. 1996 Jul; 5(7):1047-50.
- Morphologic evidence for three cell types in the human spiral ganglion. Hear Res. 1996 Apr; 93(1-2):120-7.
- Vestibular symptoms in otosclerosis--correlation of otosclerotic involvement of vestibular apparatus and Scarpa's ganglion cell count. Am J Otol. 1996 Mar; 17(2):263-70.
- Tubal and tympanic openings of the peritubal cells: implications for cerebrospinal fluid otorhinorrhea. Am J Otol. 1996 Mar; 17(2):335-9.
- Correlation of hearing loss and radiologic dimensions of vestibular schwannomas (acoustic Neuromas). Am J Otol. 1996 Mar; 17(2):312-6.
- Vestibular neurectomy: retrosigmoid-intracanalicular versus retrolabyrinthine approach. Am J Otol. 1996 Mar; 17(2):253-8.
- The use of the temporoparietal fascial flap in temporal bone reconstruction. Am J Otol. 1996 Jan; 17(1):137-42.
- Patterns of degeneration in the human cochlear nerve. Hear Res. 1995 Oct; 90(1-2):192-201.
- Endolymphatic sac tumors: histopathologic confirmation, clinical characterization, and implication in von Hippel-Lindau disease. Laryngoscope. 1995 Aug; 105(8 Pt 1):801-8.
- Fibrous dysplasia of the temporal bone: ten new cases demonstrating the spectrum of otologic sequelae. Am J Otol. 1995 Jul; 16(4):408-19.
- Molecular genetic screening for children at risk of neurofibromatosis 2. Arch Otolaryngol Head Neck Surg. 1995 May; 121(5):590-1.
- The impact of dexamethasone on hearing loss in experimental pneumococcal meningitis. Pediatr Infect Dis J. 1995 Feb; 14(2):93-6.
- Non-paraganglioma jugular foramen lesions masquerading as glomus jugulare tumors. Am J Otol. 1995 Jan; 16(1):94-8.
- Vestibular neuritis. Otolaryngol Head Neck Surg. 1995 Jan; 112(1):162-72.
- Ménière's disease. Eur Arch Otorhinolaryngol. 1995; 252(2):63-75.
- Acute and chronic mastoiditis: clinical presentation, diagnosis, and management. Curr Clin Top Infect Dis. 1995; 15:204-29.
- Degenerative changes in the organ of Corti and lateral cochlear wall in experimental endolymphatic hydrops and human Menière's disease. Acta Otolaryngol Suppl. 1995; 519:47-59.
- Supranuclear efferent synapses on outer hair cells and Deiters' cells in the human organ of Corti. Hear Res. 1994 Dec; 81(1-2):49-56.
- Temporal bone pathology in a case of Cogan's syndrome. Laryngoscope. 1994 Sep; 104(9):1135-42.
- Histopathology of ossicular implants. Otolaryngol Clin North Am. 1994 Aug; 27(4):813-33.
- Serum antibody to inner ear proteins in patients with progressive hearing loss. Correlation with disease activity and response to corticosteroid treatment. JAMA. 1994 Aug 24-31; 272(8):611-6.
- Otopathology in a case of multichannel cochlear implantation. Laryngoscope. 1994 Mar; 104(3 Pt 1):299-303.
- Hearing loss. N Engl J Med. 1993 Oct 07; 329(15):1092-102.
- The National Temporal Bone, Hearing, and Balance Pathology Resource Registry. Arch Otolaryngol Head Neck Surg. 1993 Aug; 119(8):846-53.
- Survival of Scarpa's ganglion in the profoundly deaf human. Ann Otol Rhinol Laryngol. 1993 Jun; 102(6):425-8.
- The temporoparietal fascial flap in head and neck reconstruction. Arch Otolaryngol Head Neck Surg. 1993 Jun; 119(6):618-23.
- The localization of synaptophysin in the organ of Corti of the human as shown by immunoelectron microscopy. Acta Otolaryngol. 1993 May; 113(3):312-7.
- Postnatal maturation of human spiral ganglion cells: light and electron microscopic observations. Hear Res. 1993 May; 67(1-2):211-9.
- Progression of hearing loss in experimental pneumococcal meningitis: correlation with cerebrospinal fluid cytochemistry. J Infect Dis. 1993 Mar; 167(3):675-83.
- High jugular bulb: implications for posterior fossa neurotologic and cranial base surgery. Ann Otol Rhinol Laryngol. 1993 Feb; 102(2):100-7.
- Patterns of innervation of outer hair cells in a chimpanzee: II. Efferent endings. Hear Res. 1993 Jan; 64(2):217-21.
- Patterns of innervation of outer hair cells in a chimpanzee: I. Afferent and reciprocal synapses. Hear Res. 1993 Jan; 64(2):184-90.
- Diameter of the cochlear nerve in deaf humans: implications for cochlear implantation. Ann Otol Rhinol Laryngol. 1992 Dec; 101(12):988-93.
- Preservation of hearing and facial nerve function in resection of acoustic neuroma. Laryngoscope. 1992 Oct; 102(10):1153-8.
- Long-term hearing results in patients after surgical removal of acoustic tumors with hearing preservation. Am J Otol. 1992 Mar; 13(2):134-6.
- Primary malignant melanoma of the external auditory canal: a case report with presentation as an aural polyp. Am J Otol. 1992 Mar; 13(2):194-6.
- Hearing loss and pneumococcal meningitis: an animal model. Laryngoscope. 1991 Dec; 101(12 Pt 1):1285-92.
- Bilateral acoustic neurofibromatosis (neurofibromatosis 2): a disorder distinct from von Recklinghausen's neurofibromatosis (neurofibromatosis 1). Ann Otol Rhinol Laryngol. 1991 Oct; 100(10):830-4.
- Histopathologic correlation of spiral ganglion cell count and new bone formation in the cochlea following meningogenic labyrinthitis and deafness. Ann Otol Rhinol Laryngol. 1991 Sep; 100(9 Pt 1):712-6.
- Correlation between antibodies to type II collagen and treatment outcome in bilateral progressive sensorineural hearing loss. Lancet. 1991 Feb 16; 337(8738):387-9.
- The hypotympanum and infralabyrinthine cells in chronic otitis media. Laryngoscope. 1991 Feb; 101(2):137-41.
- Idiopathic sudden sensorineural hearing loss and postnatal viral labyrinthitis: a statistical comparison of temporal bone findings. Ann Otol Rhinol Laryngol. 1990 Dec; 99(12):969-76.
- Degeneration of cochlear neurons as seen in the spiral ganglion of man. Hear Res. 1990 Nov; 49(1-3):141-54.
- Pathology of peripheral vestibular disorders in the elderly. Am J Otolaryngol. 1990 Jul-Aug; 11(4):213-27.
- Carcinoid tumors of the middle ear. Ann Otol Rhinol Laryngol. 1990 Jul; 99(7 Pt 1):547-52.
- Synaptic morphology of inner and outer hair cells of the human organ of Corti. J Electron Microsc Tech. 1990 Jun; 15(2):187-96.
- Morphometric analysis of normal human spiral ganglion cells. Ann Otol Rhinol Laryngol. 1990 May; 99(5 Pt 1):340-8.
- Histopathology of the ears, eyes, and brain in Norrie's disease (oculoacousticocerebral degeneration). Am J Otolaryngol. 1990 Mar-Apr; 11(2):112-24.
- Morphology of synapses at the base of hair cells in the organ of Corti of the chimpanzee. Ann Otol Rhinol Laryngol. 1990 Mar; 99(3 Pt 1):215-20.
- The pathology of peripheral vestibular disorders in the elderly. Ear Nose Throat J. 1989 Dec; 68(12):930, 933-4.
- Radiographic diagnosis, surgical treatment, and long-term follow-up of cholesterol granulomas of the petrous apex. Laryngoscope. 1989 Sep; 99(9):896-907.
- Survival of spiral ganglion cells in profound sensorineural hearing loss: implications for cochlear implantation. Ann Otol Rhinol Laryngol. 1989 Jun; 98(6):411-6.
- Dimensions of the extended facial recess. Ann Otol Rhinol Laryngol. 1989 May; 98(5 Pt 1):336-8.
- Correlation of otosclerotic foci and degenerative changes in the organ of Corti and spiral ganglion. Am J Otolaryngol. 1989 Jan-Feb; 10(1):1-12.
- Multichannel cochlear implants in partially ossified cochleas. Ann Otol Rhinol Laryngol Suppl. 1988 Sep-Oct; 135:3-7.
- Comparative anatomy of the cochlea and auditory nerve in mammals. Hear Res. 1988 Aug; 34(3):253-66.
- Application of electron microscopy to human otopathology. Ultrastructural findings in neural presbycusis, Menière's disease and Usher's syndrome. Acta Otolaryngol. 1988 May-Jun; 105(5-6):411-9.
- Quantification of human spiral ganglion cells by serial section reconstruction and segmental density estimates. Am J Otolaryngol. 1988 Mar-Apr; 9(2):47-51.
- A new design for intraoperative facial nerve monitoring. Otolaryngol Head Neck Surg. 1988 Mar; 98(3):258-61.
- Treatment of sensorineural hearing loss by cochlear implantation. Annu Rev Med. 1988; 39:491-502.
- Innervation densities of inner and outer hair cells of the human organ of Corti. Evidence for auditory neural degeneration in a case of Usher's syndrome. ORL J Otorhinolaryngol Relat Spec. 1988; 50(6):363-70.
- Preservation of hearing in surgical removal of acoustic neuromas of the internal auditory canal and cerebellar pontine angle. Laryngoscope. 1987 Nov; 97(11):1287-94.
- Ultrastructural findings in a case of Menière's disease. Ann Otol Rhinol Laryngol. 1987 Jul-Aug; 96(4):449-54.
- Postnatal growth of the human temporal bone. Implications for cochlear implants in children. Ann Otol Rhinol Laryngol. 1986 Jul-Aug; 95(4 Pt 1):356-64.
- Kartagener's syndrome. A blinded, controlled study of cilia ultrastructure. Arch Otolaryngol Head Neck Surg. 1986 Jun; 112(6):646-50.
- Tuberculosis of the middle ear: review of the literature with an instructive case report. Rev Infect Dis. 1986 May-Jun; 8(3):403-10.
- Histopathology of the inner ear in Usher's syndrome as observed by light and electron microscopy. Ann Otol Rhinol Laryngol. 1986 May-Jun; 95(3 Pt 1):313-8.
- A study of postmortem autolysis in the human organ of Corti. J Comp Neurol. 1985 Jul 15; 237(3):333-42.
- Causes of failure of mastoidectomy for chronic otitis media. Laryngoscope. 1985 Apr; 95(4):410-3.
- Diagnosis of cerebellopontine angle tumors. Clin Neurosurg. 1985; 32:177-213.
- Incidence of reciprocal synapses on outer hair cells of the human organ of Corti. Ann Otol Rhinol Laryngol. 1984 May-Jun; 93(3 Pt 1):247-50.
- Histological considerations in implant patients. Arch Otolaryngol. 1984 Mar; 110(3):160-3.
- Obliteration of the mastoid in the treatment of tumors of the temporal bone. Ann Otol Rhinol Laryngol. 1984 Jan-Feb; 93(1 Pt 1):6-12.
- Fetal rhabdomyoma of the larynx. Arch Otolaryngol. 1983 Dec; 109(12):821-6.
- Serial section reconstruction of the neural poles of hair cells in the human organ of Corti. II. outer hair cells. Laryngoscope. 1983 Jun; 93(6):780-91.
- Serial section reconstruction of the neural poles of hair cells in the human organ of Corti. I. Inner hair cells. Laryngoscope. 1983 May; 93(5):599-614.
- Chemodectomas (nonchromaffin paragangliomas) of the glomus jugulare, glomus vagale and carotid body. Ann Otol Rhinol Laryngol. 1982 Nov-Dec; 91(6 Pt 1):666-9.
- Ectopic parathyroid tissue in the hypopharyngeal mucosa (pyriform sinus). Head Neck Surg. 1982 Sep-Oct; 5(1):70-4.
- Cochleosaccular degeneration of the inner ear and progressive cataracts inherited as an autosomal dominant trait. Laryngoscope. 1982 Sep; 92(9 Pt 1):1028-37.
- Invasive external otitis. Report of 21 cases and review of the literature. Am J Med. 1981 Oct; 71(4):603-14.
- Treatment of carcinoma of the epiglottis. Ann Otol Rhinol Laryngol. 1981 Sep-Oct; 90(5 Pt 1):442-8.
- Ultrastructural histopathology in a case of human ototoxicity due to loop diuretics. Acta Otolaryngol. 1981 May-Jun; 91(5-6):399-414.
- Temporal bone histopathology in human ototoxicity due to loop diuretics. Scand Audiol Suppl. 1981; 14 Suppl:201-13.
- Reciprocal synapses at the base of outer hair cells in the organ of corti of man. Ann Otol Rhinol Laryngol. 1981 Jan-Feb; 90(1 Pt 1):12-7.
- Histopathology of Pseudomonas osteomyelitis of the temporal bone starting as malignant external otitis. Am J Otolaryngol. 1980 Nov; 1(5):359-71.
- Carcinoid tumor of the middle ear. Am J Clin Pathol. 1980 Jun; 73(6):816-23.
- Extracranial technique for temporal bone removal. Ann Otol Rhinol Laryngol. 1980 May-Jun; 89(3 Pt 1):251-2.
- Pathoembryology of the middle ear. Birth Defects Orig Artic Ser. 1980; 16(4):181-209.
- Electron microscopic findings in presbycusic degeneration of the basal turn of the human cochlea. Otolaryngol Head Neck Surg (1979). 1979 Nov-Dec; 87(6):818-36.
- Considerations in clinical application of electrocochleography in 1978. Laryngoscope. 1979 May; 89(5 Pt 1):698-704.
- Treatment of syphilitic hearing loss. Combined penicillin and steroid therapy in 29 patients. Ann Otol Rhinol Laryngol. 1979 Mar-Apr; 88(2 Pt 1):160-5.
- Intercellular fluid pathways in the organ of Corti of cat and man. Ann Otol Rhinol Laryngol. 1979 Jan-Feb; 88(1 Pt 1):2-11.
- Hearing loss as a sequela of meningitis. Laryngoscope. 1978 May; 88(5):739-55.
- Detection of syphilitic hearing loss. Arch Otolaryngol. 1978 Feb; 104(2):63-5.
- Intercellular junctions in the organ of Corti. Ann Otol Rhinol Laryngol. 1978 Jan-Feb; 87(1 Pt 1):70-80.
- Viral particles in nasopharyngeal carcinoma. Laryngoscope. 1977 Nov; 87(11):1932-7.
- Positive Hennebert's sign in Meniere's disease. Arch Otolaryngol. 1977 Sep; 103(9):524-30.
- Electron microscopic observations in a case of long-standing profound sensorineural deafness. Ann Otol Rhinol Laryngol. 1977 Jul-Aug; 86(4 Pt 1):507-17.
- Pseudocellulitis of the orbit. Ann Otol Rhinol Laryngol. 1977 Jan-Feb; 86(1 Pt 1):86-8.
- Tight and gap junctions in a vertebrate inner ear. Am J Anat. 1976 Nov; 147(3):281-301.
- Vertigo of delayed onset after sudden deafness. Ann Otol Rhinol Laryngol. 1975 Nov-Dec; 84(6):841-6.
- Hearing loss of acquired syphilis: diagnosis confirmed by incudectomy. Laryngoscope. 1975 Nov; 85(11 pt 1):1888-97.
- Positive fistula sign with an intact tympanic membrane. Clinical report of three cases and histopathological description of vestibulofibrosis as the probable cause. Arch Otolaryngol. 1974 Oct; 100(4):273-8.
- Fine structural localization of acetylcholinesterase in the olfactory mucosa in guinea pig and rabbit. Ann Otol Rhinol Laryngol. 1974 Jan-Feb; 83(1):55-64.
- Fine structural localization of acetylcholinesterase in sensory and motor neurons of the muscle receptor organ in homarus. J Comp Neurol. 1970 Dec; 140(4):399-419.
- Autoradiographic evidence for epithelial origin of glucose-rich components of the basement membrane (basal lamina) and basement lamella in the skin of Fundulus heteroclitus. Z Zellforsch Mikrosk Anat. 1970; 106(3):398-411.
- A reinterpretation of the structure and development of the basement lamella: an ordered array of collagen in fish skin. Dev Biol. 1969 Oct; 20(4):304-31.
- A reinterpretation of the structure and development of the basement lamella: an ordered array of collagen in fish skin. Dev Biol. 1969 Oct; 20(4):304-31.
- Observations on the organization of the dendritic processes and receptor terminations in the abdominal muscle receptor organ of Homarus. J Comp Neurol. 1969 Sep; 137(1):19-31.
- Observations on the abdominal stretch receptor and the fine structure of associated axo-dendritic synapses and neuromuscular junctions in homarus. J Comp Neurol. 1968 Mar; 132(3):419-43.
Show More
Show Less
