Darlene A. Dartt, Ph.D.
Professor of Ophthalmology, Department of Ophthalmology
Harold F. Johnson Research Scholar and Director
Dr. Dartt studies the neural regulation of tear production, focusing on the cellular signaling pathways that nerves and growth factors use to stimulate protein secretion from the lacrimal gland and mucin secretion from conjunctival goblet cells. Her goal is to identify the signaling pathways used to stimulate secretion under normal conditions and to determine the dysfunction of these pathways in dry eye, LASIK, allergic conjunctivitis, and infection. A major area of her research is the role of conjunctival goblet cells in inflammation and the active resolution of inflammation.