Marlene L. Durand,
MD
Massachusetts Eye and Ear
Director of Infectious Diseases
Harvard Medical School
Associate Professor of Ophthalmology
Associate Professor of Medicine
marlene_durand@meei.harvard.edu
For investigator inquiries only
About My Research
Centers/Research Area Affiliations
Biography
Dr. Durand's research interests include multidrug-resistant organisms, endophthalmitis, infectious causes of uveitis, invasive otitis externa, osteomyelitis of the mandible, and prevention of surgical site infections after major ENT surgery. In collaboration with her colleagues, she has published over 100 original articles and book chapters, primarily on eye and ENT infections, as well as a textbook on endophthalmitis.
Publications powered by Harvard Catalyst Profiles
- Eye Infections. N Engl J Med. 2023 Dec 21; 389(25):2363-2375.
- Molecular Detection and Typing of Treponema pallidum in Non-Ocular Samples from Patients with Ocular Syphilis. Ocul Immunol Inflamm. 2023 Oct 05; 1-5.
- Corticosteroid Use in Otolaryngology: Current Considerations During the COVID-19 Era. Otolaryngol Head Neck Surg. 2022 11; 167(5):803-820.
- Infectious Keratitis in 2021. JAMA. 2021 Oct 05; 326(13):1319-1320.
- Pneumonia, urinary tract infection, bacteremia, and Clostridioides difficile infection following major head and neck free and pedicled flap surgeries. Oral Oncol. 2021 11; 122:105541.
- Isavuconazole Treatment of Invasive Fungal Sinusitis: A Post Hoc Analysis of the SECURE and VITAL Trials. Clin Infect Dis. 2021 09 15; 73(6):e1380-e1383.
- A Cluster of Corneal Donor Rim Cultures Positive for Achromobacter Species Associated With Contaminated Eye Solution. Cornea. 2021 Feb 01; 40(2):223-227.
- Prophylactic antibiotics after endoscopic sinus surgery for chronic rhinosinusitis: a randomized, double-blind, placebo-controlled noninferiority clinical trial. Int Forum Allergy Rhinol. 2021 07; 11(7):1047-1055.
- Predicting length of stay in head and neck patients who undergo free flap reconstruction. Laryngoscope Investig Otolaryngol. 2020 Jun; 5(3):461-467.
- Postoperative care in an intermediate-level medical unit after head and neck microvascular free flap reconstruction. Laryngoscope Investig Otolaryngol. 2019 Feb; 4(1):39-42.
- Case of late-onset, relapsing surgical site infection related to a venous coupler placed during free flap reconstruction for major head and neck cancer. Head Neck. 2018 04; 40(4):E29-E32.
- Human Bot Fly Infestation of the Eyelid. Ophthalmic Plast Reconstr Surg. 2018 Jan/Feb; 34(1):e36.
- Risk factors for thirty-day readmission following flap reconstruction of oncologic defects of the head and neck. Laryngoscope. 2018 02; 128(2):343-349.
- Bacterial and Fungal Endophthalmitis. Clin Microbiol Rev. 2017 07; 30(3):597-613.
- The role of infection and antibiotics in chronic rhinosinusitis. Laryngoscope Investig Otolaryngol. 2017 02; 2(1):36-42.
- Intravenous Drug Use-Associated Endophthalmitis. Ophthalmol Retina. 2017 May - Jun; 1(3):192-199.
- Novel Phagocytosis-Resistant Extended-Spectrum ß-Lactamase-Producing Escherichia coli From Keratitis. JAMA Ophthalmol. 2016 Nov 01; 134(11):1306-1309.
- Surgical Site Infections in Major Head and Neck Surgeries Involving Pedicled Flap Reconstruction. Ann Otol Rhinol Laryngol. 2017 Jan; 126(1):20-28.
- Perioperative Deep Vein Thrombosis Risk Stratification. Otolaryngol Head Neck Surg. 2017 01; 156(1):118-121.
- Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir. Ocul Immunol Inflamm. 2018; 26(2):199-203.
- Endogenous Endophthalmitis in the American and Korean Population: An 8-year Retrospective Study. Ocul Immunol Inflamm. 2018; 26(4):496-503.
- CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 20-2016. A 50-Year-Old Man with Cloudy Vision, Hearing Loss, and Unsteadiness. N Engl J Med. 2016 Jun 30; 374(26):2586-93.
- Risk factors for surgical site infection after supraclavicular flap reconstruction in patients undergoing major head and neck surgery. Head Neck. 2016 11; 38(11):1615-1620.
- Topical Polymyxin-Trimethoprim Prophylaxis May Decrease the Incidence of Driveline Infections in Patients With Continuous-Flow Left Ventricular Assist Devices. Artif Organs. 2017 Feb; 41(2):169-175.
- Investigation-Directed Approach to Inflammatory Optic Neuropathies. Semin Ophthalmol. 2016; 31(1-2):117-30.
- Fungal Infections in Boston Keratoprosthesis Patients: Lessons Learned and Novel Developments on the Horizon. Semin Ophthalmol. 2016; 31(1-2):71-84.
- Staphylococcus aureus and its Bearing on Ophthalmic Disease. Ocul Immunol Inflamm. 2017 Feb; 25(1):111-121.
- Infections related to Actinotignum schaalii (formerly Actinobaculum schaalii): a 3-year prospective observational study on 50 cases. Clin Microbiol Infect. 2016 Apr; 22(4):388-390.
- Varicella Zoster Virus Necrotizing Retinitis in Two Patients with Idiopathic CD4 Lymphocytopenia. Ocul Immunol Inflamm. 2016 Oct; 24(5):544-8.
- The role of serological titres in the diagnosis of ocular toxoplasmosis. Acta Ophthalmol. 2016 Aug; 94(5):521-2.
- Head and neck free flap surgical site infections in the era of the Surgical Care Improvement Project. Head Neck. 2016 04; 38 Suppl 1:E392-8.
- Multinational Comparison of Prophylactic Antibiotic Use for Eyelid Surgery. JAMA Ophthalmol. 2015 Jul; 133(7):778-84.
- Invasive fungal disease of the sinus and orbit: a comparison between mucormycosis and Aspergillus. Br J Ophthalmol. 2016 Feb; 100(2):184-8.
- The time course and microbiology of surgical site infections after head and neck free flap surgery. Laryngoscope. 2015 May; 125(5):1084-9.
- Case records of the Massachusetts General Hospital. Case 32-2014. A 78-year-old woman with chronic sore throat and a tonsillar mass. N Engl J Med. 2014 Oct 16; 371(16):1535-43.
- Successful treatment of Paecilomyces lilacinus keratitis with oral posaconazole. Cornea. 2014 Jul; 33(7):747-9.
- Prophylactic postoperative antibiotics for enucleation and evisceration. Ophthalmic Plast Reconstr Surg. 2013 Jul-Aug; 29(4):281-5.
- Endophthalmitis. Clin Microbiol Infect. 2013 Mar; 19(3):227-34.
- Surgical site infections after gracilis free flap reconstruction for facial paralysis. Otolaryngol Head Neck Surg. 2012 Aug; 147(2):245-8.
- Bacterial endophthalmitis in the age of outpatient intravitreal therapies and cataract surgeries: host-microbe interactions in intraocular infection. Prog Retin Eye Res. 2012 Jul; 31(4):316-31.
- Pythium insidiosum keratitis in Israel. Eye Contact Lens. 2011 Mar; 37(2):96-8.
- Vancomycin resistance in ocular infections. Int Ophthalmol Clin. 2011; 51(4):167-81.
- Antiviral chemoprophylaxis for ocular viral infections in hematopoietic stem cell and bone marrow transplant patients. Int Ophthalmol Clin. 2011; 51(4):53-66.
- Ocular toxocariasis: advances in diagnosis and treatment. Int Ophthalmol Clin. 2011; 51(4):135-44.
- Management of a long-standing organic intracranial foreign body. Skull Base. 2010 Nov; 20(6):487-90.
- Case records of the Massachusetts General Hospital. Case 33-2010. A 22-year-old woman with blurred vision and renal failure. N Engl J Med. 2010 Oct 28; 363(18):1749-58.
- Sinogenic orbital and subperiosteal abscesses: microbiology and methicillin-resistant Staphylococcus aureus incidence. Otolaryngol Head Neck Surg. 2010 Sep; 143(3):392-6.
- Ocular syphilis among HIV-infected patients: a systematic analysis of the literature. Sex Transm Infect. 2011 Feb; 87(1):4-8.
- Ocular syphilis among HIV-infected individuals. Clin Infect Dis. 2010 Aug 15; 51(4):468-71.
- Reconstruction of a nasopharyngeal defect from cervical spine osteoradionecrosis. Skull Base. 2010 Jul; 20(4):289-92.
- Shunts to divert aqueous humor to distant epithelialized cavities after keratoprosthesis surgery. J Glaucoma. 2010 Feb; 19(2):111-5.
- Retropharyngeal abscess in the setting of immune modulation for rheumatoid arthritis. Laryngoscope. 2010; 120 Suppl 4:S131.
- An atypical case of chronic invasive fungal sinusitis and its management. Otolaryngol Head Neck Surg. 2010 Jan; 142(1):150-1.
- Successful prevention of bacterial endophthalmitis in eyes with the Boston keratoprosthesis. Cornea. 2009 Sep; 28(8):896-901.
- Extracranial infected carotid artery aneurysm. J Vasc Surg. 2009 Dec; 50(6):1484-6.
- Bacterial endophthalmitis. Curr Infect Dis Rep. 2009 Jul; 11(4):283-8.
- Low rate of endophthalmitis in a large series of open globe injuries. Am J Ophthalmol. 2009 Apr; 147(4):601-608.e2.
- Exaggerated postsurgical inflammation in a patient with insufficiently treated Addison disease. Ophthalmic Plast Reconstr Surg. 2009 Jan-Feb; 25(1):67-9.
- Enterobacter amnigenus endophthalmitis. Retin Cases Brief Rep. 2009; 3(4):409-11.
- Case records of the Massachusetts General Hospital. Case 36-2008. A 59-year-old man with chronic daily headache. N Engl J Med. 2008 Nov 20; 359(21):2267-78.
- Orbital cellulitis with abscess formation following surgical treatment of canaliculitis. Ophthalmic Plast Reconstr Surg. 2008 Jul-Aug; 24(4):314-6.
- Sudden deafness: is it viral? ORL J Otorhinolaryngol Relat Spec. 2008; 70(1):52-60; discussion 60-2.
- Fungal colonization and infection in Boston keratoprosthesis. Cornea. 2007 Jan; 26(1):9-15.
- Odontogenic orbital inflammation: clinical and CT findings--initial observations. Radiology. 2006 Apr; 239(1):187-94.
- Sudden reversible vitritis after keratoprosthesis: an immune phenomenon? Cornea. 2005 Nov; 24(8):915-9.
- Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin. Am J Ophthalmol. 2005 Sep; 140(3):552-4.
- Chronic Staphylococcus aureus infection leading to pyogenic granuloma and preventing socket re-epithelialization after orbital exenteration. Ophthalmic Plast Reconstr Surg. 2005 May; 21(3):236-8.
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 4-2005. A 35-year-old man with nasal congestion, swelling, and pain. N Engl J Med. 2005 Feb 10; 352(6):609-15.
- Primary meningococcal conjunctivitis in an adult. Cornea. 2004 Oct; 23(7):738-9.
- Clindamycin-resistant Streptococcus pyogenes: report of a case. Diagn Microbiol Infect Dis. 2004 Jul; 49(3):223-5.
- The post-endophthalmitis vitrectomy study era. Arch Ophthalmol. 2002 Feb; 120(2):233-4.
- Endophthalmitis after keratoprosthesis: incidence, bacterial causes, and risk factors. Arch Ophthalmol. 2001 Apr; 119(4):484-9.
- Candidal endophthalmitis after keratoplasty. Cornea. 2001 Mar; 20(2):226-9.
- A case of immunotherapy-responsive eastern equine encephalitis with diffusion-weighted imaging. Neurology. 2001 Feb 13; 56(3):420-1.
- Endophthalmitis. Curr Clin Top Infect Dis. 2000; 20:271-97.
- Infectious crystalline keratopathy and endophthalmitis secondary to Mycobacterium abscessus in a monocular patient with Stevens-Johnson syndrome. Am J Ophthalmol. 1999 Feb; 127(2):209-10.
- Blackflies and whitewater: onchocerciasis and the eye. Int Ophthalmol Clin. 1998; 38(1):231-40.
- AIDS and the anterior segment. Int Ophthalmol Clin. 1998; 38(1):241-63.
- [Fatal asthma. Description and study of risk factors, in the heart of an asthmatic population followed by the College of Pneumonology of the Southwest]. Rev Mal Respir. 1997 Dec; 14(6):473-80.
- Microbiologic factors and visual outcome in the Endophthalmitis Vitrectomy Study. Am J Ophthalmol. 1997 Jul; 124(1):127-30.
- The Endophthalmitis Vitrectomy Study. Arch Ophthalmol. 1996 Aug; 114(8):1025-6; author reply 1026-7.
- Infections of the eyelid, lacrimal system, conjunctiva, and cornea. Curr Clin Top Infect Dis. 1996; 16:125-50.
- Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med. 1993 Jan 07; 328(1):21-8.
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