Center/Research Area Affiliations
Dr. Chodosh illuminates the molecular pathogenesis of adenoviral ocular infection and restores vision to those with blinding, autoimmune, corneal diseases through expanding the clinical scope of the Boston Keratoprosthesis (B-KPro), a unique corneal substitute developed by Dr. Claes H. Dohlman. His group is the worldwide leader inadenoviral ocular pathogenesis. Dr. Chodosh studies the viruses that cause the most severe form of pink eye, known as epidemic keratoconjunctivitis (EKC). In particular, his group generated the first whole genome sequence for the adenoviruses that cause EKC, created the first mouse model of adenovirus keratitis, and pioneered the cornea as a model system in which to study the role of tissue fibroblasts in innate immune responses to infection.
For a full publication list, please see his CV.
Homologous recombination in E3 genes of human adenovirus species D. Singh G, Robinson CM, Dehghan S, Jones MS, Dyer DW, Seto D, Chodosh J. J Virol. 2013 Nov;87(22):12481-8.
Molecular evolution of human adenoviruses. Robinson CM, Singh G, Lee J-Y, Dehghan S, Rajaiya J, Liu EB, Yousuf MA, Betensky RA, Jones MS, Dyer DW, Seto D, Chodosh J. Sci Rep. 2013 May 9;3:1812.
Predicting the next pathogen: analysis of a novel human adenovirus. Robinson CM, Zhou X, Rajaiya J, Yousuf MA, Singh G, DeSerres JJ, Walsh MP, Wong S, Seto D, Dyer DW, Chodosh J, Jones MS. mBio. 2013;4(2):e00595-12.
Heat shock protein 27 mediated signaling in viral infection. Rajaiya J, Yousuf MA, Singh G, Stanish H, Chodosh J. Biochemistry. 2012;51:5695-702.
Analysis of human adenovirus type 19 associated with epidemic keratoconjunctivitis and its reclassification as adenovirus type 64. Zhou X, Robinson CM, Rajaiya J, Dehghan S, Seto D, Jones MS, Dyer DW, Chodosh J. Invest Ophthalmol Vis Sci. 2012;53:2804-11.
View a complete list of publications on pubmed.gov »