Research Summary

Center/Research Area Affiliations

Research Summary

An internationally trained scientist, Dr. Baranov is committed to the development of stem-cell based and molecular therapies for blinding diseases. He is designing drug-screening assays by combining pluripotent stem cell biology with tissue engineering and imaging tools. He also works on collaborative projects involving the differentiation and transplantation of pericytes and retinal ganglion cells. This work is based on his previous studies that have demonstrated that human retinal progenitor cells can be expanded in vitro while remaining the capacity to form photoreceptors. This finding contributed to the development of a cell-based therapy for retinitis pigmentosa. 

Selected Publications

For a full list of publications, please see his CV.

Interphotoreceptor matrix-poly(ε-caprolactone) composite scaffolds for human photoreceptor differentiation. Baranov P, Michaelson A, Kundu J, Carrier R. & Young MJ. J Tissue Eng, 2014; 5.

Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cellsBaranov P, Tucker B, Young MJ. Tissue Eng Part A. 2014 May; 20(9-10):1465-75

The effect of local rapamycin immunosuppression on the survival of pig retinal progenitor cells allotransplants. Abud M, Baranov P, Hicks C, Lieppman B, Sinden J, Avila M, Young M. Transl Vis Sci Technol. 2015 Sep 22;4(5):6. eCollection 2015.

A systematic approach to identify candidate transcription factors that control cell identity. D'Alessio A, Fan ZP, Wert K, Baranov P, Cohen M, Saini J, Cohick E, Charinga C, Dadon D, Hannett N, Young MJ, Temple S, Jaenisch R, Lee T, Young RA. Stem Cell Reports. 2015 Nov 10;5(5):763-75.

Decellularized retinal matrix: natural platforms for human retinal progenitor cell culture. Kundu J, Michaelson A, Talbot K, Baranov P, Carrier R, Young MJ. Acta Biomater. 2016 Feb;31:61-70.

For a complete list of publications, please visit or view the CV.