Petr Baranov, M.D., Ph.D.

Harvard Medical School

Instructor in Ophthalmology

Schepens Eye Research Institute of Mass. Eye and Ear

Investigator

Research Summary

Center/Research Area Affiliations

Biography

An internationally trained scientist, Dr. Baranov is committed to the development of stem-cell based and molecular therapies for blinding diseases. He is designing drug-screening assays by combining pluripotent stem cell biology with tissue engineering and imaging tools. He also works on collaborative projects involving the differentiation and transplantation of pericytes and retinal ganglion cells. This work is based on his previous studies that have demonstrated that human retinal progenitor cells can be expanded in vitro, while maintaining the capacity to form photoreceptors. This finding contributed to the development of a cell-based therapy for retinitis pigmentosa.

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Publications

Selected Publications

View Dr. Baranov's publications on PubMed or Google Scholar.

  1. Kundu J, Michaelson A, Talbot K, Baranov P, Carrier R, Young MJ. Decellularized retinal matrix: natural platforms for human retinal progenitor cell culture. Acta Biomater. 2016 Feb;31:61-70.
  2. D'Alessio A, Fan ZP, Wert K, Baranov P, Cohen M, Saini J, Cohick E, Charinga C, Dadon D, Hannett N, Young MJ, Temple S, Jaenisch R, Lee T, Young RA. A systematic approach to identify candidate transcription factors that control cell identity. Stem Cell Reports. 2015 Nov 10;5(5):763-75.
  3. Abud M, Baranov P, Hicks C, Lieppman B, Sinden J, Avila M, Young M. The effect of local rapamycin immunosuppression on the survival of pig retinal progenitor cells allotransplants. Transl Vis Sci Technol. 2015 Sep 22;4(5):6. eCollection 2015.
  4. Baranov P, Tucker B, Young MJ. Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells. Tissue Eng Part A. 2014 May; 20(9-10):1465-75
  5. Baranov P, Michaelson A, Kundu J, Carrier R. & Young MJ. Interphotoreceptor matrix-poly(ε-caprolactone) composite scaffolds for human photoreceptor differentiation. J Tissue Eng. 2014; 5:2041731414554139.