Blake C. Alkire, M.D., MPH

Harvard Medical School

Instructor in Otolaryngology

Massachusetts Eye and Ear

Associate Researcher, Program in Global Surgery and Social Change at Harvard Medical School and Office of Global Surgery at Mass. Eye and Ear

Research Summary

Research Area Affiliations

  • Global Surgery

Research Summary

Dr. Blake Alkire is a Research Associate for the Program in Global Surgery and Social Change at Harvard Medical School and the Office of Global Surgery at Mass. Eye and Ear. His research focuses on developing models to assess the economic cost and benefit of surgical interventions in low- and middle-income countries (LMICs).

Most recently, Dr. Alkire led modeling efforts to better understand inequities in global access to surgical care for the Lancet Commission on Global Surgery (LCoGS), which found that close to five billion people do not have access to surgery. Additional research for LCoGS included modeling the global economic burden of surgical disease, which concluded that LMICs could lose $12.3 trillion USD—up to 2% of their potential gross domestic product—due to surgically treatable conditions over the next 15 years.

He is also interested in advancing benefit-cost analysis in global surgery, most recently contributing a chapter to Disease Control Priorities which found that access to cleft lip and palate repair and cesarean delivery not only alleviates significant morbidity and mortality, but also results in net economic gains.

Select Publications

Global access to surgical care: A modelling study. Alkire BC*, Raykar NP*, Shrime MG, Weiser TG, Bickler SW, Rose JA, Nutt CT, Greenberg SL, Kotagal M, Riesel JN, Esquivel M, Uribe-Leitz T, Molina G, Roy N, Meara JG, Farmer PE. Lancet Glob Health. 2015 Jun. 3(6):e316-23.
 *Authors contributed equally.

Global economic consequences of selected surgical diseases: A modelling study. Alkire BC, Shrime MG, Dare AJ, Vincent JR, Meara JG. Lancet Glob Health. 2015 Apr 27. 3 Suppl 2:S21-7.

Head and neck cancer in South Asia: Macroeconomic consequences and the role of the head and neck surgeon. Alkire BC, Bergmark R, Chambers K, Lin DT, Deschler DG, Cheney ML, Meara JG. Head Neck. 2016 Mar 30. Epub.

Benefit-Cost Analysis for Selected Surgical Interventions in Low- and Middle-income Countries. Alkire BC, Vincent JR, Meara JG. Disease Control Priorities (Third Edition): Essential Surgery. Editors: Haile Debas, Peter Donkor, Margaret Kruk, Charles Mock, Atul Gawande, Dean Jamison. World Bank, 2015.

An assessment of sinonasal anatomic variants potentially associated with recurrent acute rhinosinusitis. Alkire BC, Bhattacharyya N. Laryngoscope. 2010 Mar. 120(3):631-4.

Obstructed labor and caesarean delivery: The cost and benefit of surgical intervention. Alkire BC, Vincent JR, Burns CT, Metzler IS, Farmer PE, Meara JG. PLoS One. 2012. 7(4):e34595.

Potential economic benefit of cleft lip and palate repair in sub-Saharan Africa. Alkire BC, Hughes CD, Nash K, Vincent JR, Meara JG. World J Surg. 2011 Jun. 35(6):1194-201.

Global Surgery 2030: Evidence and solutions for achieving health, welfare, and economic development. Meara JG, Leather AJ, Hagander L, Alkire BC, Alonso N, Ameh EA, Bickler SW, Conteh L, Dare AJ, Davies J, Mérisier ED, El-Halabi S, Farmer PE, Gawande A, Gillies R, Greenberg SL, Grimes CE, Gruen RL, Ismail EA, Kamara TB, Lavy C, Lundeg G, Mkandawire NC, Raykar NP, Riesel JN, Rodas E, Rose J, Roy N, Shrime MG, Sullivan R, Verguet S, Watters D, Weiser TG, Wilson IH, Yamey G, Yip W. Lancet. 2015 Aug 8. 386(9993):569-624.

Timing and cost of scaling up surgical services in low-income and middle-income countries from 2012 to 2030: A modelling study. Verguet S, Alkire BC, Bickler SW, Lauer JA, Uribe-Leitz T, Molina G, Weiser TG, Yamey G, Shrime MG. Lancet Glob Health. 2015 Apr 27. 3 Suppl 2:S28-37.

Neck mass in an adolescent male. Bilateral branchial anomalies of the pyriform sinus. Alkire BC, Juliano AF, Hartnick CJ. JAMA Otolaryngol Head Neck Surg. 2014 Mar; 140(3):275-6.

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2005: B.S., Vanderbilt University
2009: MPH, T.H. Chan Harvard School of Public Health
2011: M.D., Harvard Medical School

Postgraduate Training

2011 - 2012: Internship: General Surgery, Brigham and Women’s Hospital
2012 - 2016: Residency: Otolaryngology, Mass. Eye and Ear/Harvard Medical School

Professional Memberships

2012 - present: American Academy of Otolaryngology-Head and Neck Surgery
2012 - present: Triological Society

Honors (select)

2005: Phi Beta Kappa, Vanderbilt University

2005: Honors in Molecular and Cellular Biology, Vanderbilt University

2005: Honors in the College of Arts and Science, College Scholars Program, Vanderbilt University

2016: Chief Resident Teaching Award, Mass. Eye and Ear/Harvard Medical School