Mack L. Cheney, M.D.
Professor of Otology and Laryngology, Harvard Medical School
The Facial Nerve Center at Massachusetts Eye and Ear Infirmary is involved in all aspects of research regarding facial paralysis. Our projects range from clinical research studies, which look at the effectiveness of certain kinds of therapy, through basic science projects which examine nerve regeneration in laboratory models. Using an animal model, we are using highly sensitive electronic recordings to give precise facial movement data. To date, our work has yielded insight into the normal rodent facial function, and has given information regarding the rate and degree of recovery after nerve injury and repair. In the future, we will test potential treatments using this model, and hope to contribute to discoveries of new and better ways to treat our patients who suffer from facial nerve disorders.
1. Mehta R, Robinson M, Hadlock T. Development and validation of a reliable Synkinesis Assessment Questionnaire. Laryngoscope. 2007;117(5):923-6.
2. Yeh C, Bowers D, Hadlock T. Effect of FK506 on functional recovery after facial nerve injury in the rat. Arch Facial Plast Surg. 2007;9(5):333-9.
3. Mehta R, Zhang S, Hadlock T. Novel 3-D video for quantification of facial movement. Otolaryngol Head Neck Surg 2008;138(4): 468-72.
4. Hadlock T, Sabini P, Quatela V, Cheney M. Multi-staged reconstructive efforts via medical missions: keys to optimizing outcome: a commentary. Arch Facial Plast Surg. 2008;10(5):350-2.
5. Hadlock T, Cheney M. Single incision endoscopic sural nerve harvest for cross face nerve grafting. J Reconstr Microsurg 2008;16. [Epub ahead of print].
6. Heaton J, Kowaleski J, Bermejo R, Ziegler H, Ahlgren D, Hadlock T. A system for studying facial nerve function in rats through simultaneous bilateral monitoring of eyelid and whisker movements. J Neurosci Methods 2008;171:197-206.
7. Hadlock T, Kowaleski J, Lo D, Bermejo R, Ziegler HP, Mackinnon S, Heaton J. Functional assessments of the rodent facial nerve: a synkinesis model. Laryngoscope 2008;118(10):1744-9.