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3-D Virtual Model of a Human Temporal Bone

This 3-D virtual model of a human temporal bone is a powerful teaching tool for learning the complex anatomy of the human temporal bone and for relating the 2-D morphology from a histological section to the 3-D anatomy. The model was created from archival histological sections from a 14-year old male. The specimen was formalin fixed, decalcified, embedded in celloidin, serially sectioned in the axial plane at 20 microns, stained with hematoxylin and eosin, and mounted on slides. Low-power views of every fifth section through the temporal bone were digitized and imported into Amira v3.1 (Mercury Computer Systems/TGS, San Diego, CA). The sections were aligned and segmented into anatomical "structures of interest".

The 3-D model is a surface rendering of these structures of interest, which currently includes (among others) the bone and air spaces of the temporal bone; the perilymphatic and endolymphatic spaces including cochlear aqueduct and endolymphatic duct and sac; the sensory epithelia of the cochlear and vestibular labyrinths; the ossicles and tympanic membrane; the middle-ear muscles; the carotid artery; and the auditory, vestibular and facial nerves. For each of these structures, the surface transparency can be individually controlled, thereby revealing the 3-D relations between surface landmarks and underlying structure. New structures of interest can be added within the Amira software.

The 3-D surface model can also be "sliced open" at any section, and the appropriate raw histologic image superimposed on the cleavage plane. Leafing through the section stack in this way provides a powerful view of the relation between microscopic images and 3-D anatomy. The image stack can also be re-sectioned in any arbitrary plane.

The model was made under the supervision of Drs. M. Charles Liberman and Saumil Merchant by Haobing Wang and Clarinda Northrop. Model development was supported by a core grant from the NIDCD (P30 DC05209).

 

System Requirements:

The EPL 3-D viewer software has been tested on Windows XP, Windows 2000, Red Hat Linux 9 and Mac OSX (10.5). To run this software, your graphics card must support OpenGL. (Most recently-made graphics cards have OpenGL support.) To display the sections, your graphics card must support texture mapping. The model may appear flickery on certain relatively old graphics cards.

 

Installation:
 
Windows (XP):
  • Download and uncompress the setup package.
  • Double click on the setup.exe file and follow the instructions on the wizard to install .
  • The program will automatically run after the installation.

Please refer to Users Guide for how to use this software.

3-Dviewer of the Human Temporal Bone model (Win ~25MB) 
 

MacOS X (10.5):

  • Download the zipped package. The package will be automatically uncompressed by the system.
  • Go into the uncompressed the folder and double click "3DViewer_TB" or "3DViewer_VE" to run the program.

Please refer to Users Guide for how to use this software.

3-Dviewer of the Human Temporal Bone model (Mac ~27MB) 
 

 

MacOS X (10.4):
  • Download the zipped package. The package will be automatically uncompressed by the system.
  • Go into the uncompressed the folder and double click "3DViewer_TB" or "3DViewer_VE" to run the program.

Please refer to Users Guide for how to use this software.

3-Dviewer of the Human Temporal Bone model (Mac ~25MB) 

 

MacOS X (10.3):

  • Download the zipped package. The package will be automatically uncompressed by the system.
  • Double click "Install.pkg". You may need to input the administrator's password. The software package will be installed at "Applications/3Dviewer".
  • To run the software, double click "3Dviewer".
  • When the program gets started, the teaching model will be loaded automatically.
  • Please refer to Users Guide for how to use this software.

    3-Dviewer of the Human Temporal Bone model (Mac ~20MB)

    Linux:

 Download EPL 3DViewer Only:

 

 

 

Windows: