Impact of Luminance on People with AMD

SERI Protocol ID



Age-related Macular Degeneration


Alcon Corporation

Principal Investigator

Eli Peli, M.Sc., O.D.

Study Design

There will be a screening visit to determine eligibility, followed by 1 or 2 visits to perform tasks on a computer screen.

Study Objective

Visually-impaired people’s ability to see can be affected by changes in luminance and contrast. These changes can help or hinder a person’s ability to perform everyday tasks. The goal of this study is to further examine how luminance and contrast can affect visual acuity, contrast sensitivity, and our visual system’s response to blur.

Who is Eligible

Individuals diagnosed with AMD, having Visual Acuity between 20/70 and 20/200

Subject Enrollment

We are currently enrolling individuals with AMD. Potential participants will be screened on their first visit to determine eligibility.

Study Procedures

If you agree to participate in this study and meet the selection criteria, you will be asked to complete a series of tasks on a computer screen, like reading letters of different sizes, and responding to brief video clips or images using response buttons. You will wear fitted goggles that reduce luminance. There will be two or three visits lasting no longer than 2.5 hours each.

For More Information

Doris Apfelbaum (617)912-2505 or
Zachary Reynolds (617)912-2503



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