Taha Jan, M.D.

Resident Taha Jan in lab coat

Hometown: Slemani, Kurdistan and Memphis, Tennessee
Undergraduate School: Vanderbilt University (Molecular and Cellular Biology)
Medical School: Stanford University School of Medicine
Research Interests: I am interested in the biology of stem cells, stem cell niches and regenerative medicine within the field of hearing biology, with the ultimate goal of reversing hearing loss. Specifically, I am interested in mechanisms of self-renewal and the role of the canonical Wnt pathway in the regeneration of endogenous putative stem/progenitor populations in the inner ear.

Publications:
Effect of obesity and medical comorbidities on outcomes after adjunct surgery for obstructive sleep apnea in cases of adenotonsillectomy failure. Chan DK, Jan TA, Koltai PJ. Arch Otolaryngol Head Neck Surg. 2012 Oct;138(10):891-6. doi: 10.1001/2013.jamaoto.197.
PMID: 23069817

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Chai R, Kuo B, Wang T, Liaw EJ, Xia A, Jan TA, Liu Z, Taketo MM, Oghalai JS, Nusse R, Zuo J, Cheng AG. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8167-72. doi: 10.1073/pnas.1202774109. Epub 2012 May 4.
PMID: 22562792

Isolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry. Jan TA, Chai R, Sayyid ZN, Cheng AG. J Vis Exp. 2011 Dec 23;(58):e3432. doi: 10.3791/3432.
PMID: 22217925

Intrinsic regenerative potential of murine cochlear supporting cells. Saku T. Sinkkonen, Renji Chai, Taha A. Jan, Byron H. Hartman, Roman Laske, Felix Gahlen, Wera Sinkkonen, Alan G. Cheng, Kazuo Oshima, Stefan Heller.  Scientific Reports. 2011 Jun 29;1:26.
PMID: 22355545

Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea. Renjie Chai, Anping Xia, Tian Wang, Taha A. Jan, Toshinori Hayashi, Olivia Bermingha-McDonogh, Alang G. Cheng. Journal of the Association for Research in Otolaryngology. 2011 April 7; 12(4):455-69.
PMID: 21472479

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. Kazim Narsinh, Andrew Lee, Ning Sun, Patricia Almeida, Shijun Hu, Taha Jan, Kitchener Wilson, Denise Leong, Jarrett Rosenberg, Mylene Yao, Joseph Wu. Journal of Clinical Investigation. 2011 Mar 1;121(3):1217-21.
PMID: 21317531

Effects of Corticosteroids on Functional Recovery and Neuron Survival After Facial Nerve Injury. David Lieberman, Taha A. Jan, Omar Ahmad, Sam P. Most. Archives of Facial Plastic Surgery. 2011 Mar-Apr;13(2):117-24.
PMID: 21079107

Genetic analysis of tongue size and taste papillae number and size in recombinant inbred strains of mice. David J. Reiner, Taha A. Jan, John D. Boughter, Cheng-Xiang Li, Lu Lu, Robert W. Williams, Robert S. Waters. Chemical Senses. 2008 Oct; 33(8): 693-707.
PMID: 18653645

A functional role for Anopheles gambiae arrestin1 in olfactory signal transduction. William B. Walker, Elaine M. Smith, Taha Jan and L. J. Zwiebel. Journal of Insect Physiology. 2008 Apr; 54(4):680-90.
PMID: 18328499

Genetic analysis of posterior medial barrel subfield (PMBSF) size in somatosensory cortex (SI) in recombinant inbred strains of mice. Taha A. Jan, Lu Lu, Cheng-Xiang Li, Robert W. Williams, Robert S. Waters. BMC Neuroscience 2008 Jan 7; vol 9: article #3.
PMID: 18179704

Early postnatal alcohol exposure reduced the size of vibrissal barrel field in rat somatosensory cortex (SI) but did not disrupt barrel field organization. Akinniran Oladehin, Cecilia P. Margret, Susan E. Maier, Cheng X. Li, Taha A. Jan, Tyson D. Chappell, Robert S. Waters.  Alcohol. 2007 Jun;41(4):253-61.
PMID: 17630086

Prenatal alcohol exposure (PAE) reduces the size of the forepaw representation in forepaw barrel subfield (FBS) cortex in neonatal rats: relationship between periphery and central representation. Cecilia P. Margret, Tyson D. Chappell, Cheng X. Li, Taha A. Jan, Shannon G. Matta, Andrea J. Elberger, Robert S. Waters. Experimental Brain Research. 2006 Jul;172(3):387-96.
PMID: 16424976