Sid Puram, M.D., Ph.D.

 

Sid Puram, MD in lab coat

Hometown: Edina, Minnesota
Undergraduate School: MIT (Biology and Neuroscience)
Medical School: Harvard Medical School
Graduate School: Ph.D. in Neurobiology from Biology and Biomedical Sciences Program, Harvard Medical School
Research Interests: Innervation of auditory and laryngeal prostheses; genetic analysis of head and neck squamous cell carcinoma; molecular drivers of dendrite growth and retraction; signaling pathways mediating tumorigenesis in glioblastoma multiforme

Publications:
Cell-intrinsic drivers of dendrite morphogenesis. Puram SV, Bonni A. Development. 2013 Dec;140(23):4657-71. doi: 10.1242/dev.087676.
PMID: 24255095

Cochlear implant outcomes in patients with superior canal dehiscence. Puram SV, Roberts DS, Niesten ME, Dilger AE, Lee DJ. Cochlear Implants Int. 2013 Sep 17. [Epub ahead of print]
PMID: 24074366

The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain. Puram SV, Kim AH, Park HY, Anckar J, Bonni A. Cell Rep. 2013 Jul 11;4(1):19-30. doi: 10.1016/j.celrep.2013.06.006. Epub 2013 Jul 3.
PMID: 23831032

Castleman disease presenting in the neck: report of a case and review of the literature. Puram SV, Hasserjian RP, Faquin WC, Lin HW, Rocco JW. Am J Otolaryngol. 2013 May-Jun;34(3):239-44. doi: 10.1016/j.amjoto.2012.11.007. Epub 2013 Feb 1. Review.
PMID: 23375540

STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. Puram SV, Yeung CM, Jahani-Asl A, Lin C, de la Iglesia N, Konopka G, Jackson-Grusby L, Bonni A. J Neurosci. 2012 Jun 6;32(23):7806-18. doi: 10.1523/JNEUROSCI.3243-11.2012.
PMID: 22674257

A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Puram SV, Riccio A, Koirala S, Ikeuchi Y, Kim AH, Corfas G, Bonni A. Genes Dev. 2011 Dec 15;25(24):2659-73. doi: 10.1101/gad.174060.111. Epub 2011 Dec 1.
PMID: 22135323

A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Puram SV, Kim AH, Ikeuchi Y, Wilson-Grady JT, Merdes A, Gygi SP, Bonni A. Nat Neurosci. 2011 Jul 3;14(8):973-83. doi: 10.1038/nn.2857.
PMID: 21725312

Novel functions for the anaphase-promoting complex in neurobiology.
Puram SV, Bonni A. Semin Cell Dev Biol. 2011 Aug;22(6):586-94. doi: 10.1016/j.semcdb.2011.03.006. Epub 2011 Mar 23. Review.
PMID: 21439392

An old dog learns new tricks: a novel function for Cdc20-APC in dendrite morphogenesis in neurons. Puram SV, Kim AH, Bonni A. Cell Cycle. 2010 Feb 1;9(3):482-5.
PMID: 20195072

STAT3 regulation of glioblastoma pathogenesis. de la Iglesia N, Puram SV, Bonni A. Curr Mol Med. 2009 Jun;9(5):580-90. Review.
PMID: 19601808

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, Bonni A. Cell. 2009 Jan 23;136(2):322-36. doi: 10.1016/j.cell.2008.11.050.
PMID: 19167333

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway.
de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Genes Dev. 2008 Feb 15;22(4):449-62. doi: 10.1101/gad.1606508. Epub 2008 Feb 7.
PMID: 18258752

Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice. Choleris E, Little SR, Mong JA, Puram SV, Langer R, Pfaff DW. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4670-5. Epub 2007 Mar 5.
PMID: 17360582

Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery. Little SR, Lynn DM, Puram SV, Langer R. J Control Release. 2005 Oct 20;107(3):449-62.
PMID: 16112767

Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9534-9. Epub 2004 Jun 21.
PMID: 15210954