Jonathan H. Talamo, M.D.

Jonathan Talamo 2014


Cornea and External Diseases


Refractive Consults



Board Certification

  • Ophthalmology

1601 Trapelo Road
Reservoir Place, Ste. 184
Waltham, MA 02451
Phone: 781-890-1023
Fax: 781-890-2507



Dr. Jonathan Talamo is a part-time member of the Mass. Eye and Ear Cornea and Refractive Surgery Service, and is well known globally as a leader, innovator and educator in the fields of cataract and refractive surgery. Dr. Talamo also serves as the Chief Medical Officer of Ocular Therapeutix, a biopharma company in Bedford, Massachusetts. A graduate of Johns Hopkins Medical School, Dr. Talamo completed his ophthalmology residency at Johns Hopkins Hospital and a clinical fellowship in cornea and external disease at Mass. Eye and Ear. He was the first surgeon in Massachusetts to perform all-laser LASIK and laser-assisted cataract surgery. Dr. Talamo has expertise with other important emerging new technologies for vision correction, including implantable contact lenses as well toric, accommodating and the multifocal intraocular lenses to correct for presbyopia and astigmatism.

Dr. Talamo was an investigator for many of the early clinical trials that led to FDA approval of lasers for vision correction with PRK and LASIK as well as image guided lasers for refractive cataract surgery. He lectures extensively on these topics and has trained hundreds of surgeons all over the world in these surgical techniques.

Throughout his career, Dr. Talamo has been actively involved in teaching and professional organizations that have set standards for Ophthalmology. He has served as an Associate Editor of the Journal of Refractive Surgery as well as on the Board of Directors of the International Society of Refractive Surgery, the Preferred Practice Patterns Panel of The American Academy of Ophthalmology (AAO), the Ethics Committee of the AAO, and as an Associate Examiner for the American Board of Ophthalmology.

Dr. Talamo published a major textbook on laser vision correction surgery, "The Excimer Manual", and co-authored the recently published "Textbook of Refractive and Laser Assisted Cataract Surgery (ReLACS)." He has authored over 80 scientific articles, reviews, and book chapters. Dr. Talamo is a recipient of Honor and Senior Achievement Awards from the American Academy of Ophthalmology, and has been cited as a "top physician" by the physician peer review organization "Best Doctors" since 2003.

Clinical Interests

All-laser refractive surgery including, LASIK and PRK, lasercataract surgery, corneal collagen crosslinking, keratoplasty, endothelial keratoplasty, keratoconus, dry eye.

Research Interests

All-laser refractive surgery including, LASIK and PRK, lasercataract surgery, corneal collagen crosslinking, keratoplasty, endothelial keratoplasty, keratoconus, dry eye.


For a full publication list, please see his CV.

Laser-assisted cataract surgery: benefits and barriers. Hatch KM, Talamo JH. Curr Opin Ophthalmol. 2014 Jan;25(1):54-61.

Pentacam HR criteria for curvature change in keratoconus and postoperative LASIK ectasia. Rubinfeld RS, Littner R, Trattler WB, Rocha K, Talamo J, Lindstrom RL. J Refract Surg. 2013 Oct;29(10):666.

Delayed epithelial closure after PRK associated with topical besifloxacin use. Talamo JH, Hatch KM, Woodcock EC. Cornea. 2013 Aug 22.

Refractive surgical problem: April consultation. Masket S, Fram NR, Shen TT, Talamo JH, Manche EE. J Cataract Refract Surg. 2013 Apr;39(4):652-5.

Optical patient interface in femtosecond laser-assisted cataract surgery: contact corneal applanation versus liquid immersion. Talamo JH, Gooding P, Angeley D, Culbertson WW, Schuele G, Andersen D, Marcellino G, Essock-Burns E, Batlle J, Feliz R, Friedman NJ, Palanker D. J Cataract Refract Surg. 2013 Apr;39(4):501-10.

Intacs for keratoconus and post-LASIK ectasia: mechanical versus femtosecond laser-assisted channel creation. Carrasquillo KG, Rand J, Talamo JH. Cornea. 2007 Sept; 26(8):956-962.

Reproducibility of flap thickness with IntraLase FS and Moria LSK-1 and M2 Microkeratomes. Talamo JH, Meltzer J, Gardner J. J Refract Surg. 2006 Jun; 22 (6): 556-61.

View a complete list of publications on>>

To learn more about Dr. Talamo, read his "Meet a Specialist" profile here.



  • Johns Hopkins Medical School, M.D.
  • AB-MD Program, Johns Hopkins University, AB


  • Wilmer Ophthalmological Institute, Johns Hopkins Hospital


  • Cornea and External Disease, Mass. Eye and Ear