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James Chodosh, M.D., MPH

Associate Director, Cornea and Refractive Surgery Service
Specialty: Cornea and External Diseases
Phone Number: 617-573-3938
Fax: 617-573-4324
Location: Mass. Eye and Ear
243 Charles Street
Boston, MA 02114
Office Hours: Monday mornings and all day Thursdays
Board Certification: Ophthalmology
College Hampshire College
Graduate School University of Oklahoma, College of Public Health
Medical School Baylor College of Medicine
Residency Ophthalmology, Baylor College of Medicine
Fellowship Corneal and External Diseases and Surgery, Bascom Palmer Eye Institute
Teaching Affiliation David G. Cogan Professor of Ophthalmology in the Field of Cornea and External Disease, Harvard Medical School
Biographical Profile:


Dr. James Chodosh is a clinician scientist internationally known and respected for his work on molecular virology, viral genomics, and viral epidemiology. In addition to serving as the Associate Director of the Cornea and Refractive Surgery Service, he directs the Boston Keratoprosthesis Clinical Programs. His clinical interests include ocular infections, chemical burns, Stevens Johnson syndrome, and keratoprosthesis surgery.

Dr. Chodosh attended medical school at Baylor College of Medicine, where he also completed his residency. He served his fellowship in Corneal and External Diseases and Surgery at Bascom Palmer Eye Institute.

His laboratory leads the field of ocular adenoviral pathogenesis and epidemic keratoconjunctivitis (EKC) and has contributed greatly to the prevention and treatment of vision loss due to infection, corneal inflammation, and scarring. Dr. Chodosh is also committed to promoting the use of the Boston Keratoprosthesis (KPro) worldwide, and has performed and assisted with artificial cornea implantation surgery in India, Italy, England, Israel, and Chile. Recently, he began a project to develop a $100 keratoprosthesis for use in underprivileged nations.

Dr. Chodosh is a committed teacher and mentor and is Fellowship Director for Mass. Eye and Ear’s Cornea Service. He has served on graduate student committees, trained postdoctoral fellows, predoctoral fellows, and residents in research, and taught several graduate courses. He has mentored 39 clinical cornea fellows, eighteen of whom now hold academic positions. He is also the author over 150 articles and book chapters, and is a four-time award recipient from Research to Prevent Blindness. 

Clinical Interests

Ocular infections, chemical burns, Stevens Johnson syndrome, keratoprosthesis surgery

Research Interests

Adenovirus pathogenesis, genomics, and evolution

Publications

For a full publication list, please see his CV.

Homologous recombination in E3 genes of human adenovirus species D. Singh G, Robinson CM, Dehghan S, Jones MS, Dyer DW, Seto D, Chodosh J. J Virol. 2013 Nov;87(22):12481-8.

Molecular evolution of human adenoviruses. Robinson CM, Singh G, Lee J-Y, Dehghan S, Rajaiya J, Liu EB, Yousuf MA, Betensky RA, Jones MS, Dyer DW, Seto D, Chodosh J. Sci Rep. 2013 May 9;3:1812.

Predicting the next pathogen: analysis of a novel human adenovirus. Robinson CM, Zhou X, Rajaiya J, Yousuf MA, Singh G, DeSerres JJ, Walsh MP, Wong S, Seto D, Dyer DW, Chodosh J, Jones MS. mBio. 2013;4(2):e00595-12.

Heat shock protein 27 mediated signaling in viral infection. Rajaiya J, Yousuf MA, Singh G, Stanish H, Chodosh J. Biochemistry. 2012;51:5695-702.

Analysis of human adenovirus type 19 associated with epidemic keratoconjunctivitis and its reclassification as adenovirus type 64. Zhou X, Robinson CM, Rajaiya J, Dehghan S, Seto D, Jones MS, Dyer DW, Chodosh J. Invest Ophthalmol Vis Sci. 2012;53:2804-11.

View a complete list of publications on pubmed.gov »