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Louis R. Pasquale, M.D.

Photo of Louis R. Pasquale, M.D.
Director, Glaucoma Service and Director, Telemedicine
Specialty: Glaucoma
Phone Number: 617-573-3674
Fax: 617-573-4300
Location: Massachusetts Eye and Ear
243 Charles Street
Boston, MA 02114
Office Hours: Thursdays 8:00am - 5:00pm; Selected Saturdays 8:00am - 4:00pm
Phone Number: 508-378-2058
Location: Mass. Eye and Ear, East Bridgewater
400 North Bedford Street
East Bridgewater, MA 02333
Office Hours: Please call to inquire.
Board Certification: Ophthalmology
Medical School State University of New York at Stony Brook
Residency Ophthalmology, Temple University Hospital
Fellowship Glaucoma, Johns Hopkins University, Wilmer Eye Institute
Teaching Affiliation Associate Professor of Ophthalmology, Harvard Medical School
Biographical Profile:

Dr. Pasquale is the Director of the Mass. Eye and Ear Glaucoma Service as well as the Ophthalmology Telemedicine program.

What would you like your patients to know about you?

I am devoted to research to prevent functional glaucoma blindness, and I believe the very best research ideas come from interacting with patients.

Clinical Interests

"Normal tension glaucoma," difficult surgical glaucoma, secondary glaucoma in the pediatric population

Research Interests

Gene-environment interactions in glaucoma


For a full publication list, please see his CV. A representative list is available through

Kang JH, Wiggs JL, Rosner BA, Haines J, Abdrabou W, Pasquale LR. Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking. Arch Ophthalmol. 2011 Jun; 129(6): 773-80.

Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, Cunningham JM, de Andrade M, Feenstra B, Feingold E, Hayes MG, Hill WG, Landi MT, Alonso A, Lettre G, Lin P, Ling H, Lowe W, Mathias RA, Melbye M, Pugh E, Cornelis MC, Weir BS, Goddard ME, Visscher PM. Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet. 2011 Jun; 43(6): 519-25.

Stein JD, Pasquale LR, Talwar N, Kim DS, Reed DM, Nan B, Kang JH, Wiggs JL, Richards JE. Geographic and climatic factors associated with exfoliation syndrome. Arch Ophthalmol. 2011 Aug; 129(8):1053-60.

Kang JH, Loomis S, Wiggs JL, Stein JD, Pasquale LR. Demographic and Geographic Features of Exfoliation Glaucoma in 2 United States-Based Prospective Cohorts. Ophthalmology. 2012 Jan; 119(1): 27-35.

Wiggs JL, Hee Kang J, Yaspan BL, Mirel DB, Laurie C, Crenshaw A, Brodeur W, Gogarten S, Olson LM, Abdrabou W, Delbono E, Loomis S, Haines JL, Pasquale LR, for the GENEVA Consortium. Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet. 2011 Dec 1; 20(23): 4707-4713.

To learn more about Dr. Pasquale, click here to read his “Meet a Specialist” profile.