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Pedram Hamrah, M.D.

Director, Ocular Surface Imaging Center
Specialties: Cornea and External Diseases
Refractive Surgery
Phone Number: 617-573-6897
Fax: 617-573-4300
Location: Massachusetts Eye and Ear
243 Charles Street
Boston, MA 02114
Office Hours: Fri 1:00pm - 5:00pm
Location: Mass. Eye and Ear, Stoneham
One Montvale Avenue
Stoneham, MA 02180
Office Hours: Wed 8:00am - 12:00pm
Board Certification: Ophthalmology
M.D. University of Cologne School of Medicine
Residency Ophthalmology, University of Louisville
Fellowship Schepens Eye Research Institute
Fellowship Cornea, External Diseases and Refractive Surgery, Mass. Eye and Ear
Teaching Affiliation Assistant Professor of Ophthalmology, Harvard Medical School
Biographical Profile:

Dr. Hamrah is an Assistant Professor of Ophthalmology with Harvard Medical School and a former Henry Allen Cornea Scholar. In addition to his full-time position on the Cornea and Refractive Surgery Service at Mass. Eye and Ear, he is an Instructor at the Immune Disease Institute of Harvard Medical School. As a clinician scientist, he is particularly interested in using live imaging to elucidate molecular and cellular mechanisms in corneal immunology, neuro-immunology, and inflammation. His research is focused on immune cell trafficking in immune and infections diseases of the cornea, including viral and microbial keratitis, refractive surgery complications, corneal transplant tolerance and rejection, as well as neurotrophic keratopathy.

Dr. Hamrah performed his residency in Ophthalmology at the University of Louisville, where he was elected chief resident during his last year. He has completed a fellowship in Ocular and Transplantation Immunology at Mass. Eye and Ear/Schepens Eye Research Institute, as well as a two-year advanced clinical fellowship in Cornea, External Diseases and Refractive Surgery at Mass. Eye and Ear.

Dr. Hamrah's research has been supported by the NIH K12 Harvard-Vision Clinical Scientist Development Program, a K08 individual award and his appointment as the first Henry Allen Cornea Scholar. He has authored over 30 peer-reviewed articles, over 10 reviews and book chapters, and has given more than 40 lectures and presentations worldwide. He has been the recipient of numerous awards, including the Claes Dohlman Society Award, the American Society of Cataract and Refractive Surgery Excellence in Research Scholarship Award, and the Association of University Professors of Ophthalmology/Research to Prevent Blindness Resident and Fellow Research Award.

Dr. Hamrah currently serves as the Cornea Section Editor of the journal Eye as well as the Assistant Editor of the journal Ocular Immunology and Inflammation. He serves on the editorial board of the Graefeís Archives of Clinical and Experimental Ophthalmology and is a peer reviewer for over 20 ophthalmology, immunology and transplantation journals. He is an Instructor at the American Academy of Ophthalmology and was recently named Chair of the ARVO Members-in-Training Committee.

Clinical Interests

Corneal and external diseases, corneal transplantation, infectious keratitis, herpetic eye diseases, corneal imaging, refractive surgery, dry eye syndrome

Research Interests

Corneal and transplantation immunology, corneal imaging, inflammatory corneal disorders


For a full publication list, please see his CV. A representative list (2006 - 2012) is available through

Hamrah P, Yamagami S, Liu Y, Zhang Q, Vora SS, Lu B, Gerard CJ, Dana MR. Deletion of the chemokine receptor CCR1 prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 2007 Mar; 48(3):1228-36.

Chen L, Hamrah P, Cursiefen C, Zhang Q, Pytowski B, Streilein JW, Dana MR. Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity 2004. Ocul Immunol Inflamm. 2007 May-Jun; 15(3):275-8.

Hamrah P, Haskova Z, Taylor AW, Zhang Q, Ksander BR, Dana MR. Local treatment with alpha-melanocyte stimulating hormone reduces corneal allorejection. Transplantation. 2009 Jul 27; 88(2):180-7.

Hamrah P, Cruzat A, Dastjerdi MH, Zheng L, Shahatit BM, Bayhan HA, Dana R, Pavan-Langston D. Corneal sensation and subbasal nerve alterations in patients with herpes simplex keratitis: an in vivo confocal microscopy study. Ophthalmology. 2010 Oct; 117(10):1930-6.

Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, Benmohamed L, Ahmed R, Wechsler SL, Ghiasi H. The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. J Virol. 2011 May; 85 (9):4184-97.