Han-Ying Peggy Chang, M.D.


Comprehensive Ophthalmology

Cornea and External Diseases



Mandarin Chinese, English

Board Certification

  • Ophthalmology

800 Huntington Ave.
Boston, MA 02115
Tuesdays. Please call 617-936-6156 to schedule an appointment.
Main Campus
243 Charles Street
Boston, MA 02114
Phone: 617-573-3202
Tuesday, Wednesday, Thursday, and Friday. Please call to schedule an appointment.



Dr. Han-Ying Peggy Chang is a specialist in corneal and external diseases as well as comprehensive ophthalmology. A full-time ophthalmologist at Mass. Eye and Ear, Dr. Chang divides her time between the Comprehensive Ophthalmology and Cataract Consultation Service and the Cornea and Refractive Surgery Service. Her clinical interests include cataract surgery, corneal disease and surgery, laser vision correction, and refractive surgery. As part of the comprehensive ophthalmology service, Dr. Chang specializes in cataract surgery as well as diagnosis and management of corneal disorders.

Dr. Chang completed her medical training from Johns Hopkins University School of Medicine where she was inducted into Alpha Omega Alpha. She completed an internship at Brigham and Women's Hospital, and then matriculated into the HMS Department of Ophthalmology Residency Training Program. Subsequently, she subspecialized in Cornea, External Disease, and Refractive Surgery at Mass. Eye and Ear as Chief Clinical Fellow, and was selected to attend the prestigious Cornea Society Advocacy Ambassador Program, Mid-Year Forum.

Dr. Chang's research interests include bioinformatics (developing software tools that help store, retrieve and analyze biological data) and the development of enhanced electronic patient medical record systems. She is interested in the use of electronic medical record systems in data collection for potential large scale epidemiological studies, and is working closely with Partners eCare to optimize this functionality in the transition to a new electronic medical record system.

Dr. Chang is a member of numerous professional societies, including the American Academy of Ophthalmology, the American Society of Cataract and Refractive Surgery, and the Cornea Society.

Clinical Interests

Comprehensive ophthalmology, cataract surgery, corneal disease and surgery, laser vision correction and refractive surgery

Research Interests

Bioinformatics and electronic medical record systems


Differentiating bilateral superior oblique paresis from sensory extorsion. Muthusamy B, Peggy Chang HY, Irsch K, Ying HS, Muthusamy K, Anwar D, Guyton DL. J AAPOS. 2013 Oct;17(5):471-6.

The genetics of keratoconus. Chang HY, Chodosh J. Semin Ophthalmol. 2013 Sep-Nov;28(5-6):275-80.

Corneal alkali burns: a review of the literature and proposed protocol for evaluation and treatment. Hamill CE, Bozorg S, Peggy Chang HY, Lee H, Sayegh RR, Shukla AN, Chodosh J. Int Ophthalmol Clin. 2013 Fall;53(4):185-94.

Ocular involvement in hospitalized patients with candidemia: Analysis at a Boston tertiary care center. Huynh N, Chang HY, Borboli-Gerogiannis S. Ocul Immunol Inflamm. 2012 Apr;20(2):100-3.

Diagnostic and therapeutic considerations in fungal keratitis. Chang HY, Chodosh J. Ophthalmol Clin. 2011 Fall;51(4):33-42.

View a list of publications on pubmed.gov>>

To learn more about Dr. Chang, read her "Meet a Specialist" profile here.



  • Computing and Information Systems, Northwestern University, BA
  • Johns Hopkins University School of Medicine, M.D.


  • Ophthalmology, Harvard Medical School


  • Cornea, External Disease, and Refractive Surgery, Mass. Eye and Ear