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HARVARD-VISION
Clinical Scientist Development Program (K12)



clinician scientist

 

Summary. The Harvard Department of Ophthalmology is one of the leading and largest academic departments of Ophthalmology in the nation and a major recipient of NIH funding. With nearly 150 full-time clinical and basic science faculty, it continues to make significant contributions to ophthalmic and vision research in virtually all basic, applied, and clinical subspecialty areas. The Harvard-Vision Clinical Scientist Development Program proposes to offer a customized and structured learning, research, and development environment to a select group of qualified clinically-trained candidates who have recently completed (or about to complete) their training, but who desire further mentored learning experience so as to become independent leading clinical scientists in their respective fields. Trainees in this program will (i) complete a core curriculum that will include the Harvard Program in Clinical Effectiveness (PCE) – a summer-long immersion program in biostatistics, epidemiology, study design, and outcomes measurement. Additional required curricular activities will include the Harvard Medical School course, HBTM 303qc “Introduction to the Visual System”, a multidisciplinary survey course focusing on the biological mechanisms (genetics, immunology, neuroscience, vascular biology) of eye disease. Candidates will also (ii) perform research in a closely mentored program under the guidance of lead mentors who are leaders in their respective fields with the express objective of allowing them to develop into independent investigators. Trainees in this program will additionally have the option of seeking an advanced degree (MS, MPH, PhD, ScD) at Harvard.

Background. The extraordinary growth and specialization that has occurred over the past several decades in the sciences has made it increasingly difficult to link the increasing divide between clinical and basic science components of ophthalmic and vision sciences. The less-than-optimal degree of cross-talk between scientists engaged in studying fundamental biological processes and clinicians providing care to patients has had multiple deleterious effects. Continued external factors are expected to impact this trend negatively for the foreseeable future. Traditional approaches, based purely on didactic curricula, to “teach” basic sciences to highly-trained clinicians are only variably effective as they offer limited opportunity to these clinicians for hands-on experience in designing and conducting studies. Additionally, many clinicians engaged in pure clinical (vs. bench-based) research have had very limited formal training in methodological aspects of clinical study design and execution.

To address these needs the Harvard-Vision Clinical Scientist Development Program is seeking to recruit and train clinician-scientists as detailed below.

We are seeking subspecialty/fellowship-trained board-certified/eligible ophthalmologists (or optometrists) to commit, at the level of Junior Faculty with 75% of their time dedicated to structured research (up to 25% clinical work) and the development program under mentorship of one of our senior faculty.  The duration of commitment will be 3-5 years based on the interests of the candidate and the nature of the mentored training program.

A position is available throughout the Harvard Ophthalmology system for July 1 of the next academic year.

Interested applicants should contact Cori O’Brien at 617-573-3311 or cori_o’brien@meei.harvard.edu for an application.  Applicants should also identify a mentor within the Harvard faculty or MIT community and contact them to discuss potential mentor relationship if accepted into the program.

In addition please submit (1) a complete curriculum vitae, (2) 1-2 page letter of intent describing how this mechanism will further your career in vision science, (4) 1-2 page Scientific Proposal (4) 3 letters of recommendation to Reza Dana, MD, MPH c/o Cori O’Brien Massachusetts Eye & Ear Infirmary 243 Charles St, Boston, MA 02114.  US citizenship or resident alien status (green card) is required for acceptance to the program.  

Application deadline is December 15 for the following July 1.

This program is funded by the National Institutes of Health.  We are an Equal Opportunity/Affirmative Action Employer.  Women & Minorities are encouraged to apply.

Scope of Research and List of Mentors

Below, are tables listing the ophthalmic subspecialty areas, and academic disciplines and related faculty, offered through the Harvard-Vision Clinical Scientist Development Program.

 
Institution Key
 

BWH

Brigham & Women’s Hospital

Children’s

Boston Children’s Hospital

HMS

Harvard Medical School

HSPH

Harvard School of Public Health

HU

Harvard University

JDC

Joslin Diabetes Center

MEEI

Massachusetts Eye & Ear Infirmary

MGH

Massachusetts General Hospital

SERI

Schepens Eye Research Institute

Table 1. Subspecialty Areas - Harvard-Vision Clinical Scientist Development Program
 

Ocular Area of Concentration
Mentors & Faculty          
(may be listed in >1 area of expertise)
Institution
 
Cornea & Anterior Segment
Pablo Argüeso, PhD
Reza Dana, MD, MSc, MPH
Darlene Dartt, PhD
Ilene Gipson, PhD
Ula Jurkunas, MD
James Zieske, PhD
SERI
MEEI & SERI
SERI
SERI
SERI
SERI
Glaucoma
Louis Pasquale, MD
Janey L. Wiggs, MD, PhD
MEEI
MEEI
Inherited Retinopathies
Eliot Berson, MD
Eric Pierce, MD, PhD
MEEI
MEEI
Low Vision
Alex Bowers, PhD
Eli Peli, OD
David G. Hunter, MD (pediatric)
SERI
SERI
Children’s
Macular Degeneration
Dean Eliott, MD
Evangelos Gragoudas, MD
Joan Miller, MD
MEEI
MEEI
MEEI
Nutrition & Disease
Susan Hankinson, ScD, MPH
Debra Schaumberg, ScD, MPH
HMS
BWH
Ocular Inflammation & Microbiology
James Chodosh, MD
Reza Dana, MD, MSc, MPH
Michael Gilmore, PhD
MEEI
MEEI & SERI
MEEI
Ocular Oncology
Evangelos Gragoudas, MD
MEEI
Pediatric Ophthalmology
David G. Hunter, MD
Children’s
Proliferative Vitreoretinopathy
 
Lloyd Paul Aiello, MD, PhD
Robert D’Amato, MD, PhD
Patricia D’Amore, PhD
Andrius Kazlauskas, PhD
Mara Lorenzi, MD
Joan Miller, MD
Lois Smith, MD, PhD
JDC
Children’s & MEEI
SERI
SERI
SERI & MGH
MEEI
Children’s
Retinal Physiology & Development
Larry Benowitz, PhD
Connie Cepko, PhD
John Dowling, PhD
Richard Masland, PhD
Children’s
HMS
HU, Biological Labs
MEEI
Tear Film & Ocular Surface
Reza Dana, MD, MSc, MPH
Darlene Dartt, PhD
Ilene Gipson, PhD
David Sullivan, PhD
James Zieske, PhD
SERI
SERI
SERI
SERI
SERI

Table 2. Academic Disciplines - Harvard-Vision Clinical Scientist Development Program
 

Academic Discipline
Mentors & Faculty          
(may be listed in >1 area of expertise)
Institution
Biostatistics & Epidemiology
Robert Glynn, ScD
Susan Hankinson, ScD, MPH
Louis Pasquale, MD
Debra Schaumberg, ScD, MPH
Meir Stampfer, MD, DrPH
BWH
HMS
MEEI
BWH
 
HSPH
Cell Biology
Ilene Gipson, PhD
Ula Jurkunas, MD
Andrius Kazlauskas, PhD
James Zieske, PhD
SERI
SERI
SERI
SERI
Clinical Trials
Francis Cook, ScD, MS
Dean Eliott, MD
Robert Glynn, ScD
Evangelos Gragoudas, MD
Joan Miller, MD
Louis Pasquale, MD
Debra Schaumberg, MSc, MPH
HMS, Clin. Effect. Prog.
MEEI
BWH
MEEI
MEEI
MEEI
BWH
Development
John Dowling, PhD
HMS, Biological Labs
Genetics
Eliot Berson, MD
Connie Cepko
Eric Pierce, MD, PhD
Janey Wiggs, MD, PhD
MEEI
HMS
MEEI
MEEI
Immunology & Microbiology
Pablo Argüeso, PhD
James Chodosh, MD
Reza Dana, MD, MSc, MPH
Michael Gilmore, PhD
SERI
MEEI
MEEI & SERI
MEEI
Matrix Remodeling & Angiogenesis
Lloyd Paul Aiello, MD, PhD
Patricia D’Amore, PhD
Reza Dana, MD, MSc, MPH
Joan Miller, MD
JDC
SERI
MEEI & SERI
MEEI
Neurobiology
Larry Benowitz, PhD
John Dowling, PhD
Richard Masland, PhD
Children’s
HMS, Biological Labs
MEEI
Optics
Alex Bowers, PhD
Eli Peli, OD
SERI
SERI
Physiology
Darlene Dartt, PhD
Ilene Gipson, PhD
David Hunter, MD, PhD
David Sullivan, PhD
James Zieske, PhD
SERI
SERI
Children’s
SERI
SERI
Vascular & Endothelial Biology
Lloyd Paul Aiello, MD, PhD
Patricia D’Amore, PhD
Mara Lorenzi, MD
Lois Smith, MD, PhD
JDC
SERI
SERI & MGH
Children’s